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Supplemental Information

Rat concussion model

Rat concussion model - behavior, laboratory

DOI: 10.7287/peerj.preprints.2037v1/supp-1

Figure 1

Device for mild traumatic brain injury using a rat as subject. The components of the devices are a vertical guide tube for the dropped weight and an acryl panel to absorb impact.

DOI: 10.7287/peerj.preprints.2037v1/supp-2

Figure 2

Finding of magnetic resonance imaging after mild traumatic brain injury. There were no significant cerebral hemorrhage, intracranial hemorrhage, and diffuse axonal injury.

DOI: 10.7287/peerj.preprints.2037v1/supp-3

Figure 3

Movement latency on metal grid was delayed after mild traumatic brain injury (p<0.05). The latency of pre-MTBI was 0.94 ± 1.41 second, but the latency of post-MTBI was 5.26 ± 11.39 second.

DOI: 10.7287/peerj.preprints.2037v1/supp-4

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Ho Jeong Kim conceived and designed the experiments, performed the experiments, analyzed the data, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Soo Jeong Han conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

1. Ethics Committee of Ewha Medical Research Institute

2. Approval No; ESM 14-0252

Data Deposition

The following information was supplied regarding data availability:

The raw data has been supplied as a Supplemental Dataset.


This work was supported by a National Research Foundation of Korea (NRF) grant funded by the Korean government (NRF-2013R1A1A2059711) and Research Grant of Alumni Chapters of Medical College of Ewha Womans University in 2015. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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