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Supplemental Information

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Wei Chen conceived and designed the experiments, wrote the paper, prepared figures and/or tables.

Dong An conceived and designed the experiments, prepared figures and/or tables.

Hong Xu performed the experiments.

Xiaoxin Cheng performed the experiments.

Shiwei Wang analyzed the data.

Weizhi Yu performed the experiments.

Deqin Yu performed the experiments.

Dan Zhao performed the experiments, prepared figures and/or tables.

Yiping Sun contributed reagents/materials/analysis tools.

Wuguo Deng contributed reagents/materials/analysis tools.

Yiyuan Tang contributed reagents/materials/analysis tools.

Shengming Yin conceived and designed the experiments, wrote the paper, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

The Tab of Animal Experimental Ethical Inspection - Number: L20140021

Data Deposition

The following information was supplied regarding data availability:

The raw data has been supplied as a Supplemental Dataset.

Funding

This work was supported by grants from the National Natural Science Foundation of China (31201724). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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