Perception of the risk of adverse reactions to analgesics: Differences between medical students and residents

Pain and Palliative care clinic, Anesthesiology Service, University Hospital Dr Jose E Gonzalez, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico
Posgraduate Division of the Faculty of Chemical Science, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico
DOI
10.7287/peerj.preprints.1890v1
Subject Areas
Anesthesiology and Pain Management, Pharmacology, Public Health, Science and Medical Education
Keywords
Adverse Drug Reactions, Risk Perception, Medical Students, Morphine, NSAIDs, Mexico
Copyright
© 2016 Castillo-Guzman et al.
Licence
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ Preprints) and either DOI or URL of the article must be cited.
Cite this article
Castillo-Guzman S, González-Santiago O, Delgado-Leal IA, Lozano-Luévano GE, Reyes-Rodríguez MJ, Elizondo-Solis CV, Nava-Obregón TA, Palacios-Ríos D. 2016. Perception of the risk of adverse reactions to analgesics: Differences between medical students and residents. PeerJ Preprints 4:e1890v1

Abstract

Background. Medications are not exempt from adverse drug reactions (ADR) and how the physician perceives the risk of prescription drugs could influence their availability to report ADR and their prescription behavior. Methods. We assess the perception of risk and the occurrence of ADR associated with COX2-Inbitors, paracetamol, NSAIDs, and morphine in medical students and residents. Results. The analgesic with the highest risk perception was morphine, while the drug with the least risk perceived was paracetamol. Addiction was perceived as the most probable adverse effects developed by morphine. In the case of NSAIDs, the main adverse effect perceived was GI bleeding. Discussion. Our findings show that medical students give higher risk scores than residents toward risk due to analgesics. It is probable that both groups of students have morphinophobia, although more studies are necessary to confirm this. Continuing training and informing physicians about ADRs is necessary since the lack of training is known to induce inadequate use of drugs.

Author Comment

This is a preprint submission to PeerJ Preprints.

Supplemental Information

Raw data Risk perception to analgesics 2016

DOI: 10.7287/peerj.preprints.1890v1/supp-1