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Additional Information

Competing Interests

The authors declare that they have no competing interests

Author Contributions

Thomas Penzel conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Ingo Fietze conceived and designed the experiments, performed the experiments, prepared figures and/or tables, iRB.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

IRB of Charite Universitätsmedizin Berlin

Data Deposition

The following information was supplied regarding data availability:

The raw data are stored in propriatory format with the systems used.

Funding

The authors received funding from the institution (Charité). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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