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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Concita Cantarella analyzed the data, wrote the paper, performed the computation work.

Rachele Tamburino performed the experiments.

Nunzia Scotti conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Teodoro Cardi conceived and designed the experiments, performed the experiments, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Nunzio D'Agostino conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, performed the computation work.

Funding

This work was funded by Ministry of Education, University and Research, PON Project GenHORT (PON02_00395_3215002) and was supported by the PON R&C 2007-2013 grant funded by the Italian Ministry of Education, University and Research in cooperation with the European Funds for the Regional Development (FESR). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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