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Supplemental Information

Appendix 1: QIICR Iowa Head and Neck Clinical Data DICOM SR Template

DOI: 10.7287/peerj.preprints.1541v3/supp-1

Appendix 2: QIICR PET SUV measurements of interest and their corresponding codes

DOI: 10.7287/peerj.preprints.1541v3/supp-2

Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Andriy Fedorov conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, prepared figures and/or tables, reviewed drafts of the paper.

David Clunie conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Ethan Ulrich conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Christian Bauer conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Andreas Wahle conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Bartley Brown conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Michael Onken conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Jörg Riesmeier conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Steve Pieper conceived and designed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Ron Kikinis conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

John Buatti conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Reinhard R. Beichel conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

University of Iowa IRB #200503706

Data Deposition

The following information was supplied regarding data availability:

Data: QIN-HEADNECK collection of The Cancer Imaging Archive (TCIA), access instructions: https://wiki.cancerimagingarchive.net/display/Public/QIN-HEADNECK

Source code:

- 3D Slicer: http://github.org/Slicer/Slicer

- 3D Slicer PET DICOM Extension: http://wiki.slicer.org/slicerWiki/index.php/Documentation/Nightly/Modules/DICOMPETSUVPlugin

- 3D Slicer PET Tumor Segmentation extension: http://wiki.slicer.org/slicerWiki/index.php/Documentation/4.5/Extensions/PETTumorSegmentation

- 3D Slicer PET-IndiC extension: http://wiki.slicer.org/slicerWiki/index.php/Documentation/Nightly/Extensions/PET-IndiC

- Iowa2DICOM conversion tools: https://github.com/QIICR/Iowa2DICOM

Funding

This project was supported in part by funding from National Institutes of Health, National Cancer Institute, through grants U24 CA180918 (Quantitative Image Informatics for Cancer Research, QIICR), U01 CA140206, and U01 CA151261. Part of the infrastructure and services used at the University of Iowa are supported by the National Institutes of Health (NIH) Clinical and Translational Science Award (CTSA) program, grant U54 TR001356. The contents are solely the responsibility of the authors and do not necessarily represent the official views of the NCI/NIH. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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