From sporadic to global: The changing face of H5N8
Department of Biomedical Sciences, University of Westminster, London, United Kingdom
- Published
- Accepted
- Subject Areas
- Bioinformatics, Evolutionary Studies, Virology
- Keywords
- H5N8, viral phylogenetics, H5, hemagglutinin, neuraminidase, influenza subtypes
- Copyright
- © 2015 Dalby
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ PrePrints) and either DOI or URL of the article must be cited.
- Cite this article
- 2015. From sporadic to global: The changing face of H5N8. PeerJ PrePrints 3:e1489v1 https://doi.org/10.7287/peerj.preprints.1489v1
Abstract
The H5N8 influenza subtype is a relatively new highly pathogenic avian influenza. Until the recent Korean outbreak of H5N8 the viral subtype had only been detected sporadically. This paper looks at the multiple reassortment events between H5 hemagglutinin and N8 neuraminidase segments that explain the breaks in the history of the H5N8 subtype, especially in the United States and that show that the recent reassortment has produced an outbreak that has very different characteristics to previous H5N8 outbreaks.
Author Comment
Submitted to PeerJ as a peer reviewed article.