Essential design modeling for scientific software development

Software design and its engineering is essential for bioinformatics software impact. We propose a new approach ‘Butterfly’, for the betterment of modeling of scientific software solutions by targeting key developmental points: intuitive, graphical user interface design, stable methodical implementation and comprehensive output presentation. The focus of research was to address following three key points: 1) differences and different challenges required to change from traditional to scientific software engineering, 2) scientific software solution development needs feedback and control loops following basic engineering principles for implementation and 3) software design with new approach which helps in developing and implementing a comprehensive scientific software solution. We validated the approach by comparing old and new bioinformatics software solutions. Moreover, we have successfully applied our approach in the design and engineering of different well applied and published Bioinformatics and Neuroinformatics tools including DroLIGHT, LS-MIDA, Isotopo, Ant-App-DB, GenomeVX and Lipid-Pro.