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Additional Information

Competing Interests

The authors declare that they have no competing interests.

Author Contributions

Weirong Li conceived and designed the experiments, prepared figures and/or tables, reviewed drafts of the paper.

Xiuwei Wang performed the experiments, wrote the paper.

Zhen Guan performed the experiments, prepared figures and/or tables.

Yufei Zheng analyzed the data, contributed reagents/materials/analysis tools.

Xiaodong Zhang contributed reagents/materials/analysis tools.

Jing Shi analyzed the data.

Bo Niu conceived and designed the experiments, reviewed drafts of the paper.

Animal Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

All experimental procedures were reviewed and approved by the Animal Ethics Committee of the Capital Institute of Pediatrics (ref CIP2009012).


This study was supported by the Natural Science Foundation of Shanxi Province of China (Grant No. 2013011052-5) and the Shanxi Provincial health department of Science and Technique Foundation ( Grant No. 201202047). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

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