Ecological validity of methods to assess walking ability in Multiple Sclerosis
Institut of Neuroimmunology and Multiple Sclerosis (INIMS), University Medical Center Hamburg-Eppendorf, Hamburg, Germany
- Published
- Accepted
- Subject Areas
- Neurology
- Keywords
- Ecological validity, walking, Multiple Sclerosis
- Copyright
- © 2015 Stellmann
- Licence
- This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ PrePrints) and either DOI or URL of the article must be cited.
- Cite this article
- 2015. Ecological validity of methods to assess walking ability in Multiple Sclerosis. PeerJ PrePrints 3:e1032v1 https://doi.org/10.7287/peerj.preprints.1032v1
Abstract
Mobility is one of the most important bodily functions of persons with Multiple Sclerosis. Cross-sectional data as well as preliminary findings from a short baseline to treatment studies indicate a poor ecological validity of clinical gait tests. Real-life use of accelerometer should be used to assess mobility in MS. Advanced MRI techniques such as probabilistic tractography might help to narrow the gap between structural imaging as a marker of neurodegeneration and real-life performance in Multiple Sclerosis.
Author Comment
This presentation was a contribution to the 2nd Winter Symposium of the Human Motion Project and it is part of "Human Motion Project" PeerJ collection.