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Additional Information

Competing Interests

The authors declare they have no competing interests.

Author Contributions

Evgeni Mekov conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.

Yanina Slavova conceived and designed the experiments, contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Adelina Tsakova performed the experiments, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Marianka Genova performed the experiments, contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Dimitar Kostadinov contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Delcho Minchev contributed reagents/materials/analysis tools, reviewed drafts of the paper.

Dora Marinova contributed reagents/materials/analysis tools, wrote the paper, reviewed drafts of the paper.

Human Ethics

The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):

Medical University-Sofia Research Ethics Commission approved the study (#2976/2014)

Data Deposition

The following information was supplied regarding the deposition of related data:

Files will be uploaded to FigShare.

Funding

This manuscript is part of a PhD project, which is partially funded by Medical University – Sofia, Sofia, Bulgaria (grant number 15-D/2014, project number 22-D/2014). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.


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