Preprints (not yet peer-reviewed)

21 downloads
128 views

Background. Efficient communication requires that signals are well transmitted and perceived in a given environment. Natural selection therefore drives the evolution of different signals in different environments. In addition, environmental heterogeneity at small...

["Evolutionary Studies"]
doi:10.7287/peerj.preprints.3298v1
20 downloads
82 views

Specific regulation and activation of focal adhesion kinase (FAK) are thought to be important for focal adhesion formation, and activation of Rho-kinase has been suggested to play a role in determining the effects of FAK on the formation of stress fibers and focal...

["Cell Biology","Molecular Biology"]
doi:10.7287/peerj.preprints.3297v1
25 downloads
56 views

We present GenotypeAnalytics (GA), a RESTFul service that makes it possible to mine association rules from Single Nucleotide Polymorphism (SNP) datasets using standard web browsers. GA can speed up and simplify the analysis of this massive amount of data, highlighting...

["Bioinformatics","Computational Biology","Data Mining and Machine Learning","Data Science","World Wide Web and Web Science"]
doi:10.7287/peerj.preprints.3299v1
37 downloads
103 views

We used 637 species from six taxonomic classes to identify the pattern(s) of diversification, occurring in the North Andean Block estimating phylogenetic relationships, divergence times, dispersal-vicariance events, and ancestral distributions. We assessed four...

["Biogeography","Evolutionary Studies"]
doi:10.7287/peerj.preprints.3296v1
12 downloads
63 views

Primary care accounts for the majority of patient contact within the NHS. Over time medical science and healthcare needs change, which may lead to differences in how patients are treated in primary care for good or ill. In this study over 700 million consultations...

["Health Policy","Public Health"]
doi:10.7287/peerj.preprints.3295v1
17 downloads
70 views

REDCap (Research Electronic Data Capture) is one of the most popular web-based applications to support data capture for research studies and registries. i2b2 (Informatics for Integrating Biology and the Bedside) is a widely adopted data warehouse to re-use clinical...

["Data Science","Databases"]
doi:10.7287/peerj.preprints.3294v1
10 downloads
67 views

Australian mekosuchines (Crocodylia; Crocodyloidea) with their wide diversity of cranial shape and inferred hunting strategies present a fascinating window into the diversification processes of crocodilians. This includes lingering questions as to the extent of...

["Ecology","Evolutionary Studies","Paleontology"]
doi:10.7287/peerj.preprints.3293v1
36 downloads
86 views

Atmospheric deposition represents a major vector of both macro- and micro-nutrients to the oligotrophic open oceans, potentially imposing a profound impact on the functioning of the microbial community. Whereas responses of the prokaryotes to atmospheric deposition...

["Ecology","Marine Biology","Microbiology","Climate Change Biology"]
doi:10.7287/peerj.preprints.3292v1
58 downloads
274 views

In industry, the yeast Rhodotorula mucilaginosa is commonly used for the production of carotenoids. The production of carotenoids is important because they are used as natural colorants in food and some carotenoids are precursors of retinol (vitamin A). However,...

["Biotechnology","Genomics","Microbiology","Mycology","Plant Science"]
doi:10.7287/peerj.preprints.3219v2
1,340 downloads
4,143 views

Forecasting is a common data science task that helps organizations with capacity planning, goal setting, and anomaly detection. Despite its importance, there are serious challenges associated with producing reliable and high quality forecasts — especially when...

["Data Science"]
doi:10.7287/peerj.preprints.3190v2
27 downloads
93 views

Background.The importance of assessing body fat variables and physical fitness tests play an important role in monitoring the level of activity and physical fitness of the general population. The objective of this study was to develop reference norms to evaluate...

["Global Health","Health Policy","Kinesiology","Pediatrics","Public Health"]
doi:10.7287/peerj.preprints.3291v1
13 downloads
59 views

MTopGo is a novel algorithm of module identification for PPI Network analysis, it is designed to consider two key aspects of these models, the topological properties of the network and the apriori knowledge about the proteins involved, represented by GO annotations....

["Bioinformatics","Algorithms and Analysis of Algorithms","Network Science and Online Social Networks"]
doi:10.7287/peerj.preprints.3289v1
42 downloads
122 views

Personalized medicine, i.e. a medicine focused on the individual and proactive in nature, promises an improved health care by customizing the treatment according to patient needs. The methods to analyze data, model knowledge and store interpretable results vary...

["Bioinformatics"]
doi:10.7287/peerj.preprints.3290v1
21 downloads
111 views

Propensities for different amino acids within a protein site change in the course of evolution, so that an amino acid deleterious in a particular species may be acceptable at the same site in a different species. Here, we study the amino acid-changing variants...

["Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.3211v2
89 downloads
381 views

Two complementary GIS-based functions are designed and implemented to assess the expected degree of loss due to the occurrence of flood events. Each function processes institutional thematic layers and allows decision makers first to quantify the physical and the...

["Spatial and Geographic Information Systems","Programming Languages"]
doi:10.7287/peerj.preprints.2228v2
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