Preprints (not yet peer-reviewed)

A significant portion of biomedical literature is represented in a manner that makes it difficult for consumers to find or aggregate content through a computational query. One approach to facilitate reuse of the scientific literature is to structure this information...

["Bioinformatics","Data Mining and Machine Learning","Data Science"]
doi:10.7287/peerj.preprints.3469v1
57 downloads
159 views

The area under the receiver operating characteristic (ROC) curve (AUC) is commonly used for assessing the discriminative ability of prediction models even though the measure is criticized for being clinically irrelevant and lacking an intuitive interpretation....

["Epidemiology","Statistics"]
doi:10.7287/peerj.preprints.3468v1
11 downloads
48 views

Unknown sequences, or gaps, are largely present in most published genomes across public databases. Gap filling is an important finishing step in de novo genome assembly, especially in large genomes. The gap filling problem is nontrivial and while many computational...

["Bioinformatics","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.3467v1
112 downloads
199 views

Information on the genetic control of the quality traits of soft wheat (Triticum aestivum L. em. Thell) is essential for breeding. Gluten strength is a measure of quality and has particular relevance to soft wheat as identity-preserved programs for strong-gluten...

["Agricultural Science","Genetics","Plant Science"]
doi:10.7287/peerj.preprints.3466v1
209 downloads
1,298 views

Long-term time series are necessary to better understand population dynamics, assess species' conservation status, and make management decisions. However, population data are often expensive, requiring a lot of time and resources. When is a population time series...

["Aquaculture, Fisheries and Fish Science","Conservation Biology","Ecology","Natural Resource Management"]
doi:10.7287/peerj.preprints.3168v3
23 downloads
54 views

The mitochondrial genome of moss Mielichhoferia elongata has been sequenced and assembled with Spades genome assembler. It consists of 100,342 base pairs and has practically the same gene set and its order as in other known bryophyte chondriomes. The genome contains...

["Biodiversity","Evolutionary Studies","Genomics","Plant Science","Taxonomy"]
doi:10.7287/peerj.preprints.3465v1
12 downloads
48 views

Most cropland in the U.S. is characterized by large monocultures, whose productivity is maintained through a strong reliance on costly tillage, external fertilizers, and pesticides ( Schipanski et al., 2016 ) . Despite this, farmers have developed a regenerative...

["Agricultural Science","Biodiversity","Ecology","Entomology","Soil Science"]
doi:10.7287/peerj.preprints.3464v1
9 downloads
56 views

Ornithogalum mosaic virus (OrMV) has a wide host range and affects the production of a variety of ornamentals. In this study, the coat protein (CP) gene of OrMVwas used to investigate the molecular mechanisms underlying the evolution of this virus. The 36 OrMV...

["Agricultural Science","Evolutionary Studies","Microbiology","Virology","Population Biology"]
doi:10.7287/peerj.preprints.3463v1
59 downloads
152 views

Horizontal gene transfer has had major impacts on the biology of a wide range of organisms from antibiotic resistance in bacteria to adaptations to herbivory in arthropods. A growing body of literature shows that horizontal gene transfer (HGT) between non-animals...

["Evolutionary Studies","Genomics"]
doi:10.7287/peerj.preprints.3462v1
20 downloads
66 views

Brachycephalus are among the smallest terrestrial vertebrates in the world. The genus encompasses 34 species endemic to the Brazilian Atlantic Rainforest, occurring mostly in montane forests, with many species showing microendemic distributions to single mountaintops....

["Zoology"]
doi:10.7287/peerj.preprints.3461v1
16 downloads
67 views

Good control of experiment variability is critical to experiment success, and many methods are available for quantifying variation in data. Popular methods for measuring variability in data typically uses a statistical distribution such as a standard normal distribution,...

["Statistics"]
doi:10.7287/peerj.preprints.3460v1
11 downloads
62 views

Purpose: This study was performed to investigate the expression pattern of Wnt inhibitory factor 1 (Wif1) during anorectal development in normal and anorectal malformation (ARM) embryos and the possible role of Wif1 in the pathogenesis of ARM. Methods: ARM was...

["Developmental Biology","Gastroenterology and Hepatology","Pediatrics"]
doi:10.7287/peerj.preprints.3459v1
47 downloads
71 views

Hemp (Cannabis sativa L.) is a traditional fiber crop, which is becoming one of the most important industrial fibers, with a promising future in many fields. To accelerate the breeding of hemp cultivars with increased fiber content, it is important to establish...

["Agricultural Science","Plant Science"]
doi:10.7287/peerj.preprints.3458v1
17 downloads
82 views

Background. The globally abundant coccolithophore, Emiliania huxleyi, plays an important ecological role in oceanic carbon biogeochemistry by forming a cellular covering of plate-like CaCO3 crystals (coccoliths) and fixing CO2. It is unknown how the cells arrange...

["Mathematical Biology"]
doi:10.7287/peerj.preprints.3457v1
159 downloads
385 views

The viability of DNA metabarcoding for assessment of freshwater macrozoobenthos has been demonstrated over the past years. It matured to a stage where it can be applied to monitoring at a large scale, keeping pace with increased high throughput sequencing (HTS)...

["Molecular Biology","Freshwater Biology"]
doi:10.7287/peerj.preprints.3456v1
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