Preprints (not yet peer-reviewed)

15 downloads
64 views

Unknown sequences, or gaps, are largely present in most published genomes across public databases. Gap filling is an important finishing step in de novo genome assembly, especially in large genomes. The gap filling problem is nontrivial and while many computational...

["Bioinformatics","Genetics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.3467v1
74 downloads
209 views

This work aims for modeling and simulating the metastasis of cancer, via the analogy between the cancer process and the board game Go. In the game of Go, black stones play first, could correspond to metastasis of cancer. Moreover, playing white stones on the second...

["Bioinformatics","Biophysics","Computational Biology","Mathematical Biology","Computational Science"]
doi:10.7287/peerj.preprints.3434v1
245 downloads
328 views

Blockchain technology can be utilized to improve gun control without changing existing laws. Firearm related mortality is at epidemic levels in the United States and not only has a significant impact upon public health, it also creates a large financial burden....

["Health Policy","Public Health","Legal Issues","Computational Science"]
doi:10.7287/peerj.preprints.3407v1
338 downloads
866 views

The sharing and re-use of data has become a cornerstone of modern science. Multiple platforms now allow quick and easy data sharing. So far, however, data publishing models have not accommodated on-going scientific improvements in data: for many problems, datasets...

["Computational Biology","Ecology","Computational Science","Data Science"]
doi:10.7287/peerj.preprints.3401v1
33 downloads
127 views

The hemagglutinin subtypes from Influenza A can be divided into distinct lineages. This is important for tracing the evolutionary history of the gene. It allows regional lineages to be identified and studied. The process of lineage identification depends on phylogenetic...

["Bioinformatics","Virology","Computational Science"]
doi:10.7287/peerj.preprints.3396v1
49 downloads
337 views

In translational medicine, the technology of RNA sequencing (RNA-seq) continues to prove powerful, and transforming the RNA-seq data into biological insights has become increasingly imperative. We present the Transcriptomics profiler for Easy Discovery (TED) toolkit,...

["Bioinformatics","Genomics","Translational Medicine","Computational Science","Data Science"]
doi:10.7287/peerj.preprints.3385v1
18 downloads
95 views

While biochemistry evidently affects the growth rate of cells, many biochemists routinely ignore population variation, just like population geneticists usually ignore causal details of biochemistry that underpin a change in growth rate caused by a mutation. A true...

["Biochemistry","Cell Biology","Computational Biology","Oncology","Computational Science"]
doi:10.7287/peerj.preprints.3371v1
86 downloads
240 views

Language and music are peculiar human behaviors. We spend a large portion of our lives speaking, reading, processing speech, performing music and listening to tunes. At the same time, we still know very little as to why and how these structured behaviors emerged...

["Anthropology","Evolutionary Studies","Neuroscience","Psychiatry and Psychology","Computational Science"]
doi:10.7287/peerj.preprints.3366v1
170 downloads
188 views

Nowadays Mobile phones are becoming more popular in our daily lives. Mobile technology has a great effect on human life. Our daily tasks are dependent on mobile devices. Memory Management (MM), Security and Performance plays an important role in every handheld...

["Human-Computer Interaction","Computational Science"]
doi:10.7287/peerj.preprints.3344v1
12,287 downloads
41,116 views

The website Sci-Hub provides access to scholarly literature via full text PDF downloads. The site enables users to access articles that would otherwise be paywalled. Since its creation in 2011, Sci-Hub has grown rapidly in popularity. However, until now, the extent...

["Bioinformatics","Legal Issues","Science and Medical Education","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.3100v2
30 downloads
149 views

Network diffusion approaches are frequently used for identifying the relevant disease genes and for prioritizing the genes for drug sensitivity predictions. Majority of these studies rely on networks representing a single type of information. However, using multiplex...

["Computational Biology","Computational Science"]
doi:10.7287/peerj.preprints.3339v1
38 downloads
123 views

Celiac disease is a chronic condition, which can be described as inflammatory and autoimmune. The well-known treatment is a lifelong gluten-free diet, but it can be not totally effective for a high percentage of the patients. The aim of this work is to approach...

["Bioinformatics","Biotechnology","Computational Biology","Statistics","Computational Science"]
doi:10.7287/peerj.preprints.3315v1
55 downloads
127 views

Coarse-grained simulations enable the study of membrane proteins in the context of their native environment but require reliable parameters. The CgProt force field is assessed by comparing the potentials of mean force for sidechain insertion in a DOPC bilayer to...

["Biophysics","Computational Biology","Computational Science"]
doi:10.7287/peerj.preprints.3306v1
65 downloads
296 views

Background. The number of individuals of each species in a given location forms the basis for many sub-fields of ecology and evolution. Data on individuals, including which species, and where they're found can be used for a large number of research questions. Global...

["Bioinformatics","Ecology","Computational Science"]
doi:10.7287/peerj.preprints.3304v1
23 downloads
119 views

Recently, we showed that the controlled NOT function is a permutation that cannot be inverted in subexponential time in the worst case [Quantum Information Processing. 16:149 (2017)]. Here, we show that such a condition can provoke biased interpretations from Bell’s...

["Computational Science"]
doi:10.7287/peerj.preprints.3302v1
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