Preprints (not yet peer-reviewed)

151 downloads
1,097 views

The timely publication of scientific results is essential for dynamic advances in science. The ubiquitous availability of computers which are connected to a global network made the rapid and low-cost distribution of information through electronic channels possible....

["Human-Computer Interaction","Computer Education","Computer Networks and Communications","Digital Libraries","World Wide Web and Web Science"]
doi:10.7287/peerj.preprints.2648v2
57 downloads
109 views

Historically, handling insects has usually involved their being killed, but non-lethal approaches are necessary when evaluating the biology of such organisms. Anesthesia has been used as one of these non-lethal approaches. Two common anesthetics used in this way...

["Entomology","Toxicology","Anaesthesiology and Pain Management"]
doi:10.7287/peerj.preprints.2874v1
107 downloads
531 views

A detailed review of a recent data science book by Hadley Wickham and Garrett Grolemund is developed herein. Technical book reviews should provide a guide to the readers, a sense of the appropriate audience, the specifics of the software/language, and identify...

["Computational Biology","Data Science"]
doi:10.7287/peerj.preprints.2873v1
33 downloads
551 views

Despite recent algorithmic improvements, learning the optimal structure of a Bayesian network from data is typically infeasible past a few dozen variables. Fortunately, domain knowledge can frequently be exploited to achieve dramatic computational savings, and...

["Artificial Intelligence","Data Mining and Machine Learning","Data Science","Distributed and Parallel Computing"]
doi:10.7287/peerj.preprints.2872v1
183 downloads
721 views

"Publication forms the core structure supporting the development and transmission of scientific knowledge" (Galbraith2015). Yet, with the WorldWideWeb a dominant part of current scientific publication and information-dissemination, internet "publication" is still...

["Adaptive and Self-Organizing Systems","Computer Education","Computer Networks and Communications","Digital Libraries","World Wide Web and Web Science"]
doi:10.7287/peerj.preprints.1568v13
34 downloads
178 views

A measure of statistical evidence should permit the sample size determination so that the probability M of obtaining (strong) misleading evidence can be held as low as desired. On this desideratum the p-value fails completely, as it leads either to an arbitrary...

["Bioinformatics","Epidemiology","Statistics"]
doi:10.7287/peerj.preprints.2869v1
29 downloads
122 views

Membrane proteins are the most medicinally important yet to be fully exploited pharmaceutical targets. Here druggability analyses are conducted on three different membrane proteins, namely, the human P2Y12 receptor, glycoprotein-41 that mediates the HIV-1 virus...

["Biochemistry","Bioinformatics","Biophysics","Computational Biology"]
doi:10.7287/peerj.preprints.2868v1
64 downloads
195 views

Incorrect snake identification from the observable visual traits is a major reason of death resulting from snake bites. So far no automatic classification method has been proposed to distinguish snakes by deciphering the taxonomy features of snake for the two major...

["Bioinformatics","Computational Biology","Taxonomy","Zoology"]
doi:10.7287/peerj.preprints.2867v1
28 downloads
108 views

Platycladus orientalis in China has a lifespan of one to several thousands of years. The long lifespans of trees have attracted interest in aging at the molecular level. There is little information on how the global process is controlled. In this study, the MDA...

["Genomics","Plant Science"]
doi:10.7287/peerj.preprints.2866v1
16 downloads
43 views

The visual impact of wind farm layouts has seen little consideration in the literature on the wind farm layout optimisation problem to date. Most existing algorithms focus on optimising layouts for power or cost of energy alone. In this paper, we consider the geometry...

["Artificial Intelligence"]
doi:10.7287/peerj.preprints.2864v1
20 downloads
217 views

This article describes a public data set with the three-dimensional kinematics of the whole body and the ground reaction forces (with a dual force platform setup) of subjects standing still for 60 s in different conditions, in which the vision and the standing...

["Bioengineering","Neuroscience","Kinesiology"]
doi:10.7287/peerj.preprints.2865v1
45 downloads
137 views

Emerging viruses cause a lot of fatalities as they jump to humans from other species. Here we develop a novel technique to computationally estimate an important parameter of within-host viral infection: the lifespan of infected cells. Our approach is general and...

["Bioinformatics","Computational Biology"]
doi:10.7287/peerj.preprints.2621v2
94 downloads
295 views

In this review, we present a summary of how computer modeling has been used in the development of covalent modifier drugs. Covalent modifier drugs bind by forming a chemical bond with their target. This covalent binding can improve the selectivity of the drug for...

["Biochemistry","Bioinformatics","Biophysics","Pharmacology","Computational Science"]
doi:10.7287/peerj.preprints.2857v1
49 downloads
86 views

Finding suitable forage patches in a heterogeneous landscape, where patches change dynamically both spatially and temporally could be challenging to large herbivores, especially if they have no a priori knowledge of the location of the patches. We tested whether...

["Animal Behavior","Ecology"]
doi:10.7287/peerj.preprints.2860v1
72 downloads
355 views

Zinc levels in artificial seawater are often unnaturally elevated, and thus potentially toxic to aquacultured corals. However, our knowledge of how zinc affects corals is still limited. We tested the effects of zinc supplementation (0, 1, 10 and 100 µg L–1) on...

["Aquaculture, Fisheries and Fish Science","Marine Biology","Toxicology"]
doi:10.7287/peerj.preprints.2858v1
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