Preprints (not yet peer-reviewed)

24 downloads
99 views

One of the great challenges in ecology and evolutionary biology is to explain disease, whether caused by infectious agents such as parasites and pathogens, or by the deterioration or transformation of cellular behavior and function, a prime example of the latter...

["Evolutionary Studies","Global Health","Public Health","Translational Medicine","Population Biology"]
doi:10.7287/peerj.preprints.3378v1
26 downloads
175 views

The spindle pole body (SPB) in fungi is the equivalent of the animal centrosome. A number of previous studies have identified many, if not all, components of the SPB. The SPB is the structural platform for microtubule nucleation and plays important roles, both...

["Cell Biology","Genetics"]
doi:10.7287/peerj.preprints.3377v1
13 downloads
121 views

Most evolutionary analyses or structure modeling are based upon pre-estimated multiple sequence alignment (MSA) models. From a computational point of view, it is too complex to estimate a correct alignment. Hence, increasing or identifying signal inside sequence...

["Bioinformatics"]
doi:10.7287/peerj.preprints.3376v1
30 downloads
97 views

Anthropogenic landscapes provide opportunities for ecologists to deliberately and intentionally design urban food webs. Ecologists working as full, collaborative partners with designers can construct functional food webs for urban environments that benefit society....

["Ecology","Coupled Natural and Human Systems"]
doi:10.7287/peerj.preprints.3375v1
46 downloads
107 views

The discovery of induced pluripotent stem cells (iPSCs) by Shinya Yamanaka in 2006 was heralded as a major breakthrough of the decade in stem cell research. The ability to reprogrammed human somatic cells to a pluripotent embryonic stem cell-like state through...

["Cell Biology","Developmental Biology","Genetics"]
doi:10.7287/peerj.preprints.3374v1
30 downloads
82 views

Novel sources of antimicrobial agents need to be identified to address the looming crisis of antimicrobial resistance. The overall goal of the described experiments was to determine whether extracts of exotic vegetables, mushrooms, and herbs have antimicrobial...

["Microbiology"]
doi:10.7287/peerj.preprints.3373v1
57 downloads
278 views

Dissolved organic matter (DOM) composition is a key determinant of microbial community metabolism and trophic nutrient transfer. On coral reefs, four primary groups of benthic organisms dominate photosynthetic production: corals, macroalgae, microphytobenthos,...

["Aquatic and Marine Chemistry","Biological Oceanography"]
doi:10.7287/peerj.preprints.3372v1
15 downloads
85 views

While biochemistry evidently affects the growth rate of cells, many biochemists routinely ignore population variation, just like population geneticists usually ignore causal details of biochemistry that underpin a change in growth rate caused by a mutation. A true...

["Biochemistry","Cell Biology","Computational Biology","Oncology","Computational Science"]
doi:10.7287/peerj.preprints.3371v1
40 downloads
160 views

For more than 20 years, panels of experts have recommended that universities collect and publish data on the career outcomes of Ph.D. students. However, little progress has been made. Over the past few years, a handful of universities, including those in the National...

["Science and Medical Education","Science Policy"]
doi:10.7287/peerj.preprints.3370v1
47 downloads
136 views

Similar to natural rivers, manmade inlets connect inland runoff to the ocean. Port Everglades Inlet (PEI) is a busy cargo and cruise ship port in South Florida, which can act as a source of pollution and nutrients to surrounding beaches and offshore coral reefs....

["Environmental Sciences","Genomics","Marine Biology","Microbiology"]
doi:10.7287/peerj.preprints.3369v1
63 downloads
532 views

There are few truly bad ideas in authentic science. We need to embrace science as a process- driven human endeavour to better understand the world around us. Products are important, but through better transparency, we can leverage ideas, good and bad, ours and...

["Ecology","Human-Computer Interaction","Data Science"]
doi:10.7287/peerj.preprints.3282v2
19 downloads
167 views

Although comparative studies of anuran ontogeny have provided new data on heterochrony in the life cycles of frogs, most of them have not included Colombian species. Using different staining techniques, we describe the cranial and poscranial elements development...

["Biodiversity","Developmental Biology","Evolutionary Studies","Taxonomy","Zoology"]
doi:10.7287/peerj.preprints.3368v1
35 downloads
216 views

The sixth mass extinction poses an unparalleled quantitative challenge to conservation biologists. Mathematicians and ecologists alike face the problem of developing models that can scale predictions of extinction rates from populations to the level of a species,...

["Conservation Biology","Ecology","Mathematical Biology","Statistics","Climate Change Biology"]
doi:10.7287/peerj.preprints.3367v1
51 downloads
179 views

Language and music are peculiar human behaviors. We spend a large portion of our lives speaking, reading, processing speech, performing music and listening to tunes. At the same time, we still know very little as to why and how these structured behaviors emerged...

["Anthropology","Evolutionary Studies","Neuroscience","Psychiatry and Psychology","Computational Science"]
doi:10.7287/peerj.preprints.3366v1
21 downloads
139 views

Experimenting with new and unconventional restoration methods and designs is critical to advancing the field of ecological restoration. Conventional methods cannot be considered reliable in a future with climate change-induced shifts in weather conditions, species...

["Conservation Biology","Ecology"]
doi:10.7287/peerj.preprints.3365v1
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