Preprints (not yet peer-reviewed)

26 downloads
107 views

Standard procedures for NGS data analysis involve a pre-processing step of reads quality assessment, followed by the alignment of the filtered reads to a reference genome. Typically the amount of reads that correctly maps to the specific reference genome ranges...

["Bioinformatics","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.3230v1
11 downloads
32 views

The increasing amount of -omics data leads to development of models to interpret and analyse them. A common approach consists in representing data as PPI Networks. These models can be very complex and informatics tools are needed to analyse them. In this abstract,...

["Bioinformatics"]
doi:10.7287/peerj.preprints.3229v1
23 downloads
160 views

Epilepsy is a complex brain disorder characterized by repetitive seizure events. Epilepsy patients often suffer from various and severe physical and psychological comorbidities. While general comorbidity prevalence and incidences can be estimated from epidemiological...

["Bioinformatics","Data Mining and Machine Learning","Data Science"]
doi:10.7287/peerj.preprints.3228v1
5 downloads
62 views

Previously, we revealed that several kampo medicines which are used for the patients with excess and/or medium patterns [kakkonto (TJ-1), shosaikoto (TJ-9), hangeshashinto (TJ-14), and orento (TJ-120)] decreased prostaglandin (PG)E2 by LPS-treated human gingival...

["Cell Biology","Dentistry","Pharmacology"]
doi:10.7287/peerj.preprints.3227v1
19 downloads
202 views

There has been very little effort to incorporate foliar microbiomes into plant conservation efforts even though foliar endophytes are critically important to the fitness and function of hosts. Many critically endangered plants that have been extirpated from the...

["Conservation Biology","Microbiology","Mycology","Plant Science"]
doi:10.7287/peerj.preprints.3226v1
107 downloads
344 views

Systems for collecting image data in conjunction with computer vision techniques are a powerful tool for increasing the temporal resolution at which plant phenotypes can be measured non-destructively. Computational tools that are flexible and extendable are needed...

["Agricultural Science","Bioinformatics","Computational Biology","Plant Science","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.3225v1
13 downloads
190 views

Epigenetic research focuses on understanding non-inheritable factors influencing gene regulation and covers various cellular mechanisms such as DNA methylation, histone modification, miRNA function and transcription factor binding sites. Recent advances in high-throughput...

["Bioinformatics","Computational Biology","Genetics","Molecular Biology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.3224v1
52 downloads
477 views

The geology and mineralogy of the Apollo 12 landing site has been the subject of recent studies that this research attempts to complement from a remote sensing point of view using the Moon Mineralogy Mapper (M3) sensor data, onboard the Chandrayaan-1 lunar orbiter....

["Algorithms and Analysis of Algorithms","Data Science","Scientific Computing and Simulation","Spatial and Geographic Information Systems"]
doi:10.7287/peerj.preprints.2124v2
12 downloads
140 views

Genome rearrangements have played an important role in the evolution of Yersinia pestis from its progenitor Yersinia pseudotuberculosis. Traditional phylogenetic trees for Y. pestis based on sequence comparison have short internal branches and low bootstrap supports...

["Bioinformatics","Genomics","Mathematical Biology"]
doi:10.7287/peerj.preprints.3223v1
372 downloads
3,077 views

Interbasinal stratigraphic correlation provides the foundation for all consequent continental-scale geological and paleontological analyses. Correlation requires synthesis of lithostratigraphic, biostratigraphic and geochronologic data, and must be periodically...

["Evolutionary Studies","Paleontology"]
doi:10.7287/peerj.preprints.2554v2
38 downloads
88 views

Convergent evolution can provide insights into the predictability of, and constraints on, the evolution of biodiversity. One striking example of convergence is seen in the ‘river dolphins’. The four dolphin genera that make up the ‘river dolphins’ (Inia geoffrensis,...

["Evolutionary Studies","Taxonomy","Zoology"]
doi:10.7287/peerj.preprints.3222v1
8 downloads
48 views

The immune system protects a host from foreign pathogens. In rare cases, the immune system can attack the cells of the host organism causing autoimmune diseases. We outline a computational framework that combines bioinformatics and network analysis with an emerging...

["Bioinformatics","Computational Biology","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.3217v2
7 downloads
91 views

Background. Microorganisms govern important ecosystems processes, in particular the degradation of organic matter (OM). However, microorganisms are rarely considered in efforts to monitor ecosystem health and functioning. Evidence suggests that environmental perturbations...

["Environmental Sciences"]
doi:10.7287/peerj.preprints.3221v1
33 downloads
82 views

Coastal protection, nutrient cycling, erosion control, water purification, and carbon sequestration are ecosystem services provided by salt marshes. Additionally, the salt ponds offers coastal breeding and nursery habitat to fishes and invertebrates providing abundant...

["Aquaculture, Fisheries and Fish Science","Food Science and Technology","Marine Biology","Natural Resource Management"]
doi:10.7287/peerj.preprints.3220v1
39 downloads
177 views

In industry, the yeast Rhodotorula mucilaginosa is commonly used for the production of carotenoids. The production of carotenoids is important because they are used as natural colorants in food and some carotenoids are precursors of retinol (vitamin A). However,...

["Biotechnology","Genomics","Microbiology","Mycology","Plant Science"]
doi:10.7287/peerj.preprints.3219v1
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