Preprints (not yet peer-reviewed)

Statistical and biochemical studies of the standard genetic code (SGC) have found evidence that the impact of mistranslations is minimized in a way that erroneous codes are either synonymous or code for an amino acid with similar polarity as the originally coded...

["Bioinformatics","Evolutionary Studies","Genetics"]
doi:10.7287/peerj.preprints.3270v1

Phylogenetics and population genetics are central disciplines in evolutionary biology. Both are based on the comparison of single DNA sequences, or a concatenation of a number of these. However, with the advent of next-generation DNA sequencing technologies, the...

["Bioinformatics","Computational Biology"]
doi:10.7287/peerj.preprints.3271v1

DNA metabarcoding provides species composition data for entire communities, yet information on intraspecific diversity is usually lost during data analysis. The capacity to infer intraspecific genetic diversity within whole communities would, however, represent...

["Biogeography","Bioinformatics","Molecular Biology","Freshwater Biology"]
doi:10.7287/peerj.preprints.3269v1
3 downloads
29 views

Plant defensins are known for different biological functions such as insect resistance, antibacterial, antifungal and antiviral activities. The role of plant defensins against weevils is based on inhibitor of alpha-amylase activity in weevil gut, therefore, weevils...

["Agricultural Science","Biotechnology","Genetics","Plant Science"]
doi:10.7287/peerj.preprints.3264v2

Exogenous sequence contamination presents a challenge in first-draft genomes because it can lead to non-contiguous, chimeric assembled sequences. This can mislead downstream analyses reliant on synteny, such as linkage-based analyses. Recently, the Mojave Desert...

["Bioinformatics","Computational Biology","Evolutionary Studies","Genomics","Computational Science"]
doi:10.7287/peerj.preprints.3266v3

The annual German Conference on Bioinformatics (GCB) has brought together renowned international scientists in bioinformatics, computational biology, biostatistics, biology and medicine since 1993. The 25th GCB was held in Tübingen from 18th to 21st of September...

["Bioinformatics"]
doi:10.7287/peerj.preprints.3268v1

It is now becoming feasible to determine the composition of an individual gut microbiota (gut microflora), as well as the individual genome. In addition, whole genome scale metabolic models (GEMs) exist for a range of bacteria, and also for human. In principle...

["Computational Biology","Computational Science"]
doi:10.7287/peerj.preprints.3267v1

To improve outcomes in statistics education - namely the acquisition of statistical literacy - we need a new approach to how the subject is delivered in psychology and behavioral sciences. To do this, key indicators and impacts of barriers to learning statistics...

["Psychiatry and Psychology","Science and Medical Education","Statistics"]
doi:10.7287/peerj.preprints.3265v1
24 downloads
60 views

During software maintenance, developers usually deal with a significant number of software change requests. As a part of this, they often formulate an initial query from the request texts, and then attempt to map the concepts discussed in the request to relevant...

["Software Engineering"]
doi:10.7287/peerj.preprints.3186v2
2 downloads
49 views

This document describes a methodology for continual assessment of the impact of malaria interventions, and the efficiency of the malaria programme. The methodology is designed to be implemented recurrently on a cycle of 2–5 years, with the involvement of stakeholders,...

["Epidemiology","Public Health","Science Policy"]
doi:10.7287/peerj.preprints.3263v1
1 download
4 views

Background. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease primarily affecting upper and lower motor neurons in the brain and spinal cord. The heterogeneity in the course of ALS clinical progression and ultimately survival, coupled...

["Bioinformatics","Computational Biology","Data Mining and Machine Learning","Scientific Computing and Simulation"]
doi:10.7287/peerj.preprints.3262v1
2 downloads
27 views

Scale transcends multiple levels of biological and physical organization, and is the critical factor that determines success of any scientific investigation. Specifically, the scale at which a question is posed plays a crucial role in influencing the type of experiments...

["Biochemistry","Bioengineering","Biophysics","Biotechnology","Cell Biology"]
doi:10.7287/peerj.preprints.3261v1
4 downloads
58 views

The leading cause of permanent disability in developed countries is due to neurological injuries, such as stroke. While physical rehabilitation therapy is indispensable for treating neurological disabilities, repetitive and high intensity therapies place high physical...

["Human-Computer Interaction","Computational Science"]
doi:10.7287/peerj.preprints.3255v2
1 download
4 views

Melanoma is a highly immunogenic tumor. Therefore, in recent years physicians have incorporated drugs that alter the immune system into their therapeutic arsenal against this disease, revolutionizing in the treatment of patients in an advanced stage of the disease....

["Bioinformatics","Algorithms and Analysis of Algorithms","Databases","Visual Analytics"]
doi:10.7287/peerj.preprints.3260v1
3 downloads
9 views

Irreducible Polynomials (IPs) have been of utmost importance in generation of substitution boxes in modern cryptographic ciphers. In this paper an algorithm entitled Composite Algorithm using both multiplication and division over Galois fields have been demonstrated...

["Cryptography","Scientific Computing and Simulation","Security and Privacy"]
doi:10.7287/peerj.preprints.3259v1
What is a PeerJ Preprint?

A PeerJ Preprint is a draft of an article, abstract, or poster that has not yet been peer-reviewed for formal publication. Submit a draft, incomplete, or final version of your work for free.

Submissions today can be approved by Editorial Staff and online in 24 hours.

Establish precedent. Solicit feedback. Publish updates.

Top subject areas - Preprints

Top subject areas - People

View all subject areas