Preprints (not yet peer-reviewed)

Whole-genome sequencing (WGS) of bacterial pathogens is currently widely used to support public-health investigations. The ability to assess WGS data quality is critical to underpin the reliability of downstream analyses. Sequence contamination is a quality issue...

["Bioinformatics","Genomics","Microbiology","Public Health"]
doi:10.7287/peerj.preprints.27499v1

In the era of Next-Generation Sequencing and shotgun proteomics, the sequences of animal toxigenic proteins are being generated at rates exceeding the pace of traditional means for empirical toxicity verification. To facilitate the automation of toxin identification...

["Bioinformatics","Computational Biology","Genomics"]
doi:10.7287/peerj.preprints.27498v1

Current health care systems require clinicians to spend a substantial amount of time to digitally document their interactions with their patients through the use of electronic health records (EHRs), limiting the time spent on face-to-face patient care. Moreover,...

["Bioinformatics","Data Mining and Machine Learning","Natural Language and Speech"]
doi:10.7287/peerj.preprints.27497v1
2 downloads
4 views

Conferences with contributed talks grouped into multiple concurrent sessions pose an interesting scheduling problem. From an attendee's perspective, choosing which talks to visit when there are many concurrent sessions is challenging since an individual may be...

["Artificial Intelligence","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27496v1
49 downloads
160 views

We describe a biologically-inspired research agenda with parallel tracks aimed at AI and AI safety. The bottom-up component consists of building a sequence of biophysically realistic simulations of simple organisms such as the nematode Caenorhabditis elegans, the...

["Animal Behavior","Computational Biology","Entomology","Neuroscience","Zoology"]
doi:10.7287/peerj.preprints.27321v2
44 downloads
94 views

Anatomically and physiologically, the reproductive process of gestation or egg-laying, and dietary habits in vertebrates appear to be distinct processes. An in-depth analysis of the dietary habits of vertebrates reveals that the gestation or egg-laying characteristic...

["Biophysics","Developmental Biology","Evolutionary Studies","Zoology","Anatomy and Physiology"]
doi:10.7287/peerj.preprints.27460v2
281 downloads
375 views

Possible combinations of inputs in the order of 10100 can fire (axonal spike or action potential) a neuron that has nearly 104 inputs (dendritic spines). This extreme degeneracy of inputs that can fire a neuron is associated with significant loss of information...

["Biophysics","Computational Biology","Neuroscience","Cognitive Disorders","Computational Science"]
doi:10.7287/peerj.preprints.27228v5
30 downloads
82 views

Corals provide structure and food sources vital for the maintenance of coral reef fish diversity. However, coral reefs are currently under threat from climate change, which has led to the largest recorded loss of live coral. The loss of live coral, and corresponding...

["Biodiversity","Ecology","Marine Biology"]
doi:10.7287/peerj.preprints.27491v2
27 downloads
103 views

Background The long-term success of ex-situ conservation programmes depends on husbandry and enrichment practices complemented by a robust welfare assessment protocol. Most zoos and conservation programmes continue to employ a bottom-up approach to measure animal...

["Animal Behavior","Conservation Biology"]
doi:10.7287/peerj.preprints.27495v1
18 downloads
58 views

The proliferation and differentiation of preadipocytes are regulated by microRNAs (miRNAs), hormones and other factors. This study aimed to investigate the effects of miR-331-3p on the proliferationand differentiation of preadipocytes in addition to fatty acid...

["Cell Biology","Genetics"]
doi:10.7287/peerj.preprints.27494v1
27 downloads
59 views

The reef crests of the Jardines de la Reina National Park are largely formed by Acropora palmata, but colonies of Acropora cervicornis and the hybrid Acropora prolifera are also present. This study shows spatial distribution of colonies, thickets and live fragments...

["Ecology"]
doi:10.7287/peerj.preprints.27493v1
16 downloads
52 views

Anti-fibrotic properties of ranibizumab have been well documented. As an antagonist to Vascular Endothelial Growth Factor (VEGF), ranibizumab works by binding and neutralizes all active VEGF, thus limits the progressive cell growth and proliferation. Its application...

["Molecular Biology","Ophthalmology"]
doi:10.7287/peerj.preprints.27492v1
25 downloads
72 views

Polyp activity in passive suspension feeders has been linked to several environmental factors such as hydrodynamics, water temperature and food concentration. To better elucidate the driving forces controlling polyp expansion in these organisms and the potential...

["Animal Behavior","Ecology","Marine Biology","Zoology"]
doi:10.7287/peerj.preprints.27490v1
62 downloads
188 views

Background. The spread of maize cultivation to the highlands of central Mexico was accompanied by substantial introgression from the endemic wild teosinte Zea mays ssp. mexicana, prompting the hypothesis that the transfer of beneficial variation facilitated local...

["Agricultural Science","Evolutionary Studies","Genetics","Genomics","Plant Science"]
doi:10.7287/peerj.preprints.27489v1
16 downloads
36 views

Human Skin Detection is one of the most applicable methods in human detection, face detection and so many other detections. These processes can be used in a wide spectrum like industry, medicine, security, etc. The objective of this work is to provide an accurate...

["Computer Vision","Data Mining and Machine Learning"]
doi:10.7287/peerj.preprints.27488v1
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