Prasanna Krishnamurthy

PeerJ Editor & Author

Summary

Dr. Prasanna earned his BVSc (DVM) degree with honors from Bangalore Veterinary College and completed his Masters and PhD in Veterinary Pathology from Indian Veterinary Research Institute (India's premier institute for Veterinary Research). He completed his postdoctoral training at Northwestern University (in Dr. Raj Kishore's laboratory) and East Tennessee State University. Before joining University of Alabama at Birmingham (UAB), he held faculty appointments at the Feinberg Cardiovascular Research Institute, Northwestern University School of Medicine, Chicago, Illinois and Houston Methodist Research Institute, Texas.

As a member of the Department of Biomedical Engineering, he directs a research program focusing on understanding mechanisms of cardiovascular diseases and developing novel therapeutic strategies to promote cardiac regeneration and repair. Dr. Krishnamurthy’s laboratory is supported through funds from National Institutes of Health (NIH-R01) and American Heart Association (GIA and Postdoctoral fellowships).

Cell Biology Molecular Biology Translational Medicine

Editorial Board Member

PeerJ - the Journal of Life & Environmental Sciences

Past or current institution affiliations

University of Alabama - Birmingham

Work details

Associate Professor

University of Alabama - Birmingham

Department of Biomedical Engineering, School of Medicine and Engineering

Dr. Prasanna's laboratory is part of the Department of Biomedical Engineering, a joint department within the School of Medicine and School of Engineering. Overall research theme in Prasanna's laboratory is to understand the mechanisms of cardiovascular diseases and develop innovative new therapies using technologies in modern medicine and bioengineering. Dr. Krishnamurthy’s laboratory focuses on several broad research areas: I) to study the molecular mechanisms involved in the progression of cardiovascular diseases II) understand how diabetes influences cardiovascular pathophysiology III) develop novel therapeutic strategies- to enhance stem cell therapeutic benefits (involving adult cells and induced pluripotent stem cells) and to promote cardiac regeneration and repair. Our laboratory uses molecular biology and modern classical research tools along with relevant surgical mouse models of cardiac diseases including myocardial infarction (LAD ligation), ischemia reperfusion and hypertrophy (ANG-II and TAC induced). Long-term goal of these studies is to identify new targets that can aid in development of future drugs and new therapies for prevention and treatment of cardiovascular disease complications in diabetes.

Websites

PeerJ Contributions

Edited 5

Academic Editor on

July 7, 2022

The expanding roles of neuronal nitric oxide synthase (NOS1)

Kundan Solanki, Sajjan Rajpoot, Evgeny E. Bezsonov, Alexander N. Orekhov, Rohit Saluja, Anita Wary, Cassondra Axen, Kishore Wary, Mirza S. Baig

https://doi.org/10.7717/peerj.13651 PubMed 35821897

November 28, 2019

Long noncoding RNA MEG3 suppresses podocyte injury in diabetic nephropathy by inactivating Wnt/β-catenin signaling

Xiajing Che, Xin Deng, Kewei Xie, Qin Wang, Jiayi Yan, Xinghua Shao, Zhaohui Ni, Liang Ying

https://doi.org/10.7717/peerj.8016 PubMed 31799068

November 1, 2016

Ischemic postconditioning and pinacidil suppress calcium overload in anoxia-reoxygenation cardiomyocytes via down-regulation of the calcium-sensing receptor

Lin Zhang, Song Cao, Shengli Deng, Gang Yao, Tian Yu

https://doi.org/10.7717/peerj.2612 PubMed 27833799

December 10, 2015

Low oxygen alters mitochondrial function and response to oxidative stress in human neural progenitor cells

Yury M. Lages, Juliana M. Nascimento, Gabriela A. Lemos, Antonio Galina, Leda R. Castilho, Stevens K. Rehen

https://doi.org/10.7717/peerj.1486 PubMed 26713239

December 3, 2015

Factors associated with extubation time in coronary artery bypass grafting patients

Abbas Rezaianzadeh, Behzad Maghsoudi, Hamidreza Tabatabaee, Sareh Keshavarzi, Zahra Bagheri, Javad Sajedianfard, Hamid Gerami, Javad Rasouli

https://doi.org/10.7717/peerj.1414 PubMed 26644972