Niraj K Nirala
Past or current institution affiliations
University of Massachusetts Medical Center at Worcester
Program in molecular Medicine
Epigenomics analysis of early onset colorectal cancer (CRC) tissues. Genetic screening to identify genes required for maintaining stemness properties of stem cells for tissue homeostasis. Understand sphingolipid-mediated mechanisms that control adult stem cells under normal homeostasis and during chronic regeneration conditions. Identifying their mammalian orthologues and exploring their involvement in colon cancer.
Riken center for Developmental Biology, Japan
December 2013 - February 2016
Investigated how α-Catenin dependent junction-actin coupling influences the cell biological and physical properties of the cells to determine the depth of epithelial invagination.