Medicine - Table of Contents

August 29, 2025

Surgery, radiotherapy and endocrine therapy for oligometastatic prostate cancer efficacy: a systematic review and network meta-analysis

Wenwei Ying, Zhenshan Ding, Yuhui He, Jianfeng Wang, Xing Chen, Xuesong Li, Yanqing Gong

https://doi.org/10.7717/peerj.19819 PubMed 40900758

August 29, 2025

Identification and validation of PSMB7 as a novel biomarker for prognosis and immune infiltrates of lung adenocarcinoma

Yan Chen, Xin Ran, Ping Fu, Jie Ao, Guihua Zhu, Lianhua Zhao, HuaLiang Xiao

https://doi.org/10.7717/peerj.19958 PubMed 40900751

August 29, 2025

Comparison of efficacy and costs between robotic-assisted and conventional thoracoscopic approaches for partial pulmonary resection: a systematic review and meta-analysis of propensity score-matched studies

Xinyang Huang, Haoxuan Li, Zihao Deng, Xinyuan Tian, Kunjiang Zhong, Xugang Zhang

https://doi.org/10.7717/peerj.19911 PubMed 40900755

August 29, 2025

Survival predictors of lung cancer patients in ICU: the importance of acute kidney injury prediction and prevention

Jue Shen, Changsong Wang, Gang Ma, Hong-Zhi Wang, Xuezhong Xing, Biao Zhu, Jianghong Zhao, Donghao Wang, Mingou Cui

https://doi.org/10.7717/peerj.19885 PubMed 40900749

August 28, 2025

Preoperative serum lipids as novel predictors for concomitant thyroid carcinoma in Graves’ disease

Xingxing Gao, Mi Liu, Yijun Wu

https://doi.org/10.7717/peerj.19915 PubMed 40895039

August 28, 2025

Outcomes of stereotactic body radiotherapy for unresectable cholangiocarcinoma: a meta-analysis and systematic review

Peng Liu, Haiyan Ye, Lijun Song, Hua Li, Mingna Fu, Zhichao Dong

https://doi.org/10.7717/peerj.19909 PubMed 40895058

August 27, 2025

A retrospective analysis of neoadjuvant chemotherapy in pneumonectomy for locally advanced central non–small cell lung cancer

Yuchen Wang, Zhihang Dang, Pu Jiang, Zhifeng Li, Jin Yang, Kun Gao, Xiaona Chen, Jifang Yao

https://doi.org/10.7717/peerj.20007 PubMed 40895065

August 27, 2025

Exploration of prognostic genes associated with lymphangiogenesis in breast cancer based on transcriptomics and experimental verification

Chen Liu, Tuo Zhang, Fushen Luo, Xiaofeng Yang, Yadong Li, Tonghui Yi, Shuang Wu, Yanbing Wang, Yueping Zhu, Kun Zhao

https://doi.org/10.7717/peerj.19890 PubMed 40895068

August 26, 2025

A closer look at severe acute kidney injury: risk factors and outcomes in PD-1/PD-L1 antibody treatment from a retrospective study

Yuemeng Wu, Lingfan Luo, Xin Sun, Xiaolan Ye, Yan Ren, Wei Zhang, Shuangshan Bu, Yiwen Li, Bin Zhu, Lina Shao

https://doi.org/10.7717/peerj.19886 PubMed 40895060

August 22, 2025

Significance of the inflammatory-immune-nutritional (IINS) score on postoperative survival and recurrence in breast cancer patients: a retrospective study

Yuan Wang, Wenxin Gao, Shan Wang, Jiajia Zhang, Jiaru Zhuang, Yibo Wu, Xiaoyan Huang, Jing He

https://doi.org/10.7717/peerj.19950 PubMed 40860681

August 22, 2025

Analysis of novel therapeutic targets and construction of a prognostic model for hepatocellular carcinoma

Pengyuan Lei, Wenfeng Li, Dafei Xie, Hua Guan, Xin Huang, Bo Huang

https://doi.org/10.7717/peerj.19899 PubMed 40860678

August 20, 2025

Survival prediction in gliomas based on MRI radiomics combined with clinical factors and molecular biomarkers

Min Hao, Junyu Yan, Xiaochun Wang, Yan Tan, Hui Zhang, Guoqiang Yang

https://doi.org/10.7717/peerj.19906 PubMed 40860684

August 20, 2025

Genome-wide discovery of circulating cell-free DNA methylation signatures for the differential diagnosis of triple-negative breast cancer

Lijing Gao, Yanbing Li, Chao Qu, Yan Dong, Qingzhen Fu, Haibo Zhou, Ning Zhao, Xianyu Zhang, Da Pang, Yashuang Zhao

https://doi.org/10.7717/peerj.19888 PubMed 40860669

August 20, 2025

Transformative insights from transcriptome analysis of colorectal cancer patient tissues: identification of four key prognostic genes

Nevin Belder, Sulgun Charyyeva, Edibe Ece Abaci Oruc, Hakiimu Kawalya, Namood-e Sahar, Nader Omidvar, Berna Savas, Arzu Ensari, Hilal Ozdag

https://doi.org/10.7717/peerj.19852 PubMed 40860666

August 19, 2025

Prognostic role and functional impact of cadherin genes in non-small cell lung cancer tumorigenesis: mechanistic insights from in silico and in vitro analyses

Quanzhong Yang, Nan Feng, Feifei Shen, Lin Bai, Rihui Li, Shuang Li, Weikai Zhang

https://doi.org/10.7717/peerj.19785 PubMed 40860670

August 18, 2025

ALDOB is a prognostic biomarker and a potential immunotherapy target for clear cell renal cell carcinoma

Wu Xu, Dali Wu, Cuilian Li, Lingfei Yan, Bo Peng, Yang Luo, Dawei Liu, Qing Li, Tao Wang

https://doi.org/10.7717/peerj.19869 PubMed 40852386

August 11, 2025

Bioinformatics analysis of laryngeal squamous cell carcinoma based on the high infection rate of HPV in Northwest China

Fan Guo, Shurong Li, Shiqi Yan, Yuqiao Zhang, Guangke Wang, Ruixia Ma

https://doi.org/10.7717/peerj.19851 PubMed 40821990

August 11, 2025

Development of a relapse-related RiskScore model to predict the drug sensitivity and prognosis for patients with ovarian cancer

Zhixin Jin, Xuegu Wang, Xiang Li, Shasha Yang, Biao Ding, Jiaojiao Fei, Xiaojing Wang, Chengli Dou

https://doi.org/10.7717/peerj.19764 PubMed 40821986

August 8, 2025

A retrospective study on beta-blocker use and outcomes in hematopoietic stem cell transplant patients

Matthew A. Bergens, John T. Bokman, Ernaya J. Johnson, Matthew L. Braun, Yan Li, Amy T. Bush, Lauren Hill, Jolien Van Opstal, Alessandro Racioppi, Rebecca Fan, Sejal Kaushik, Edwin Alyea, Nelson Chao, Taewoong Choi, Cristina Gasparetto, Mitchell Horwitz, Richard Lopez, Sendhilnathan Ramalingam, Keith Sullivan, Paul Wischmeyer, Anthony D. Sung

https://doi.org/10.7717/peerj.19822 PubMed 40792007

August 7, 2025

Insights into the molecular mechanisms underlying the function of lysyl oxidase like 1 in cancers

Xinmeng Wang, Xiaoyi Wang, Yihan Li, Dan Zhao, Jintao He, Lin Wang, Zhengliang Li, Wei Xiong

https://doi.org/10.7717/peerj.19628 PubMed 40786111

August 7, 2025

Compatibility of endoscopic examination using i-scan technology with histopathology results in laryngeal carcinoma: prospective observational study

Gracia Cintia Massie, Agung Dinasti Permana, Shinta Fitri Boesoirie, Lina Lasminingrum, Melati Sudiro, Yussy Afriani Dewi

https://doi.org/10.7717/peerj.19552 PubMed 40786107

August 6, 2025

High cyclic GMP-AMP synthase and stimulator of interferon genes in cholangiocarcinoma suggest their potential as targets for treatment

Han Ni Zin Myint, Paksiree Saranaruk, Natnicha Paungpan, Sakda Waraasawapati, Chawalit Pairojkul, Saowaluk Saisomboon, Nutsara Settha, Jatuporn Pattanachot, Seiji Okada, Wunchana Seubwai, Amnat Kitkhuandee, Kanlayanee Sawanyawisuth, Kulthida Vaeteewoottacharn

https://doi.org/10.7717/peerj.19800 PubMed 40786100

August 5, 2025

A retrospective study of automatic progressive optimization for lung cancer radiotherapy plans on the Halcyon and RayStation systems

Kainan Shao, Fenglei Du, Lingyun Qiu, Yinghao Zhang, Yucheng Li, Jieni Ding, Wenming Zhan, Weijun Chen

https://doi.org/10.7717/peerj.19831 PubMed 40786101

August 4, 2025

Comparison of survival in patients with low vs. intermediate prostate-specific antigen concentrations and development of a nomogram: a surveillance, epidemiology and end results program database study with external validation on a Chinese cohort

Jingchang Mei, Guanqun Zhu, Yu Yao, Fengju Guan, Lijiang Sun, Guiming Zhang

https://doi.org/10.7717/peerj.19823 PubMed 40777078