Research Chemist in organic synthesis and medicinal chemistry (M/F)

Centre National de la Recherche Scientifique MONTPELLIER, france

Job description

Organic chemist, the candidate will be involved as a medicinal chemist in a multidisciplinary project integrating a team of chemists (the host team), biologists (project leader) and geneticists. The objectives are the development a proof of concept on the possibilities of treating a rare disease, the Giant Axon Neuropathy, by a combined approach using small molecules (chemical approach) and genetics. - Synthesis, purification and characterization of small molecule-based chemical libraries focused on hit compounds. - Development of a fragment-based approach to explore chemical space and propose new directions to optimize these hits. - Interact with biology team to identify important structural feature for structure-activity relationships. - Present the results and work perspectives in meetings between the different partners.

Skills & Experience

Technical skills: - Knowledge of organic synthesis, multi-step syntheses - Working under inert atmosphere, purification - 1H, 13C, 31P NMR characterization, mass spectrometry - Use of Reaxys, SciFinder - Knowledge in medicinal chemistry would be appreciated Human skills: - Report writing - Written and oral reporting during meetings between the different partners - Ability to work in a demanding environment, while respecting safety rules
Show how to Apply
~ Deadline October 21, 2021 ~
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p.s. be sure to mention this PeerJ listing when applying.