The “Advances on Infantile Colic" Symposium - a PeerJ Collection


The Museo Nazionale del Risorgimento Italiano, Torino, Italy (the location of the “Advances on Infantile Colic" Symposium).

Infant colic is a very common disorder of the first three months of life in healthy infants and the worldwide incidence is 20-30% of all pediatric visits. The most common symptom of infantile colic is fussing and inconsolable crying associated with aerophagia and leg contractions occurring in the late afternoon and evening due to abdominal pain in otherwise healthy infants younger than 3 months of age. Pediatricians differentiate this condition from other diseases (gastroesophageal reflux, otitis, urinary tract infections, constipation, bowel intussuception) by performing a clinical evaluation.

The available evidence suggests that infantile colic might have several independent causes such as: feeding disorders, dismotility, lactose intolerance, cow’s milk protein allergy and food hypersensitivity , psychological factors (infant-parent interaction), and more recently gut hormones (motilin, ghrelin) and gut microflora (increased Coliform and E. Coli, and lower Lactobacillus spp). There is no consensus on the therapeutic approach of infantile colic, but these new findings open new perspectives in the management of this disorder.

The aim of the Symposium: “Advances on Infantile colic”, was to provide a critical revision of some still unresolved problems related to infantile colic. International and national experts participated in the meeting and will discuss the identification of new approaches for the treatments and prevention of negative outcomes.

The Symposium happened Oct 4-5, 2013 at the Museo Nazionale del Risorgimento Italiano.

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