PeerJ
type: channel
link: https://peerj.com/articles/
description: Articles published in PeerJ
publisher: PeerJ Inc.
publication name: PeerJ
issn: 2167-8359
items: Augmented anticancer effect and antibacterial activity of silver nanoparticles synthesized by using Taxus wallichiana leaf extract
items: Sarcopenia and echocardiographic parameters for prediction of cardiovascular events and mortality in patients undergoing maintenance hemodialysis
items: Co-occurrence of seagrass vegetation and coral colonies supports unique fish assemblages: a microhabitat-scale perspective
items: Chronic toxicity of shrimp feed added with silver nanoparticles (Argovit-4®) in Litopenaeus vannamei and immune response to white spot syndrome virus infection
items: “Double whammy”: a rapid review of rural vs urban psychosocial cancer experiences and telehealth service in five countries during the COVID-19 pandemic
items: The effects of Saccharomyces boulardii on rat colonic hypermotility induced by repeated water avoidance stress and the potential mechanism
items: Adjuvant chemoradiotherapy versus chemotherapy or radiotherapy in advanced endometrial cancer: a systematic review and meta-analysis
items: A new species and new records species of Pluteus from Xinjiang Uygur Autonomous Region, China
items: The triglycerides-glucose index and the triglycerides to high-density lipoprotein cholesterol ratio are both effective predictors of in-hospital death in non-diabetic patients with AMI
items: Reliability of kettlebell swing one and five repetition maximum

Augmented anticancer effect and antibacterial activity of silver nanoparticles synthesized by using Taxus wallichiana leaf extract
type: item
type: AcademicArticle
description: Background Taxus wallichiana is an evergreen tree species found in the Himalayan region of Pakistan. The tree possesses important secondary metabolites such as Taxol that has been implicated in treating breast, ovarian and colon cancer. Therefore keeping in view the importance of this plant species, silver nanoparticles were synthesized using Taxus wallichiana aqueous leaf extract and evaluated for their anti-bacterial and anti-cancer properties. Methods Silver (Ag) nanoparticles (NPs) were characterized for their optical, morphological and structural features using techniques such as UV-visible spectroscopy, X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) and were evaluated for their antibacterial activity and anti-cancer activity using U251 cell line. Results The study showed that the UV-absorbance peak of Ag2O NPs at 450 nm shifted to 410 nm, affirming the formation of leaf extract Ag NPs. Similarly structural studies revealed the crystalline nature of the cubic structure of the Ag crystal with an average crystallite size of 29 nm. FTIR analysis exhibited the existence of different functional elements including O-H and N-H and phenolic groups. Non-spherical glomerular shaped Taxus wallichiana Ag NPs were observed from SEM studies and EDX profile showed Ag as the main element along with constituent of biological origin. The synthesized Ag NPs showed significant antibacterial activity against Salmonella typhi, and Staphylococcus aureus. The cytotoxic activity of Ag NPs on U251 brain cancer cells showed a synergistic effect with 10 ug/mL concentration after 48 and 72 h incubation based on cell viability assay indicating promising glioblastoma drug potential.
format: application/pdf
format: text/html
creator: Aliya Yousaf
creator: Muhammad Waseem
creator: Aneela Javed
creator: Sofia Baig
creator: Bushra Ismail
creator: Ayesha Baig
creator: Irum Shahzadi
creator: Shamyla Nawazish
creator: Iftikhar Zaman
subject: Biochemistry
subject: Biotechnology
subject: Cell Biology
subject: Microbiology
description: doi:10.7717/peerj.14391
publisher: PeerJ Inc.
rights: © 2022 Yousaf et al.
abstract: Background Taxus wallichiana is an evergreen tree species found in the Himalayan region of Pakistan. The tree possesses important secondary metabolites such as Taxol that has been implicated in treating breast, ovarian and colon cancer. Therefore keeping in view the importance of this plant species, silver nanoparticles were synthesized using Taxus wallichiana aqueous leaf extract and evaluated for their anti-bacterial and anti-cancer properties. Methods Silver (Ag) nanoparticles (NPs) were characterized for their optical, morphological and structural features using techniques such as UV-visible spectroscopy, X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) and were evaluated for their antibacterial activity and anti-cancer activity using U251 cell line. Results The study showed that the UV-absorbance peak of Ag2O NPs at 450 nm shifted to 410 nm, affirming the formation of leaf extract Ag NPs. Similarly structural studies revealed the crystalline nature of the cubic structure of the Ag crystal with an average crystallite size of 29 nm. FTIR analysis exhibited the existence of different functional elements including O-H and N-H and phenolic groups. Non-spherical glomerular shaped Taxus wallichiana Ag NPs were observed from SEM studies and EDX profile showed Ag as the main element along with constituent of biological origin. The synthesized Ag NPs showed significant antibacterial activity against Salmonella typhi, and Staphylococcus aureus. The cytotoxic activity of Ag NPs on U251 brain cancer cells showed a synergistic effect with 10 ug/mL concentration after 48 and 72 h incubation based on cell viability assay indicating promising glioblastoma drug potential.
bibliographic citation: Yousaf et al. (2022) Augmented anticancer effect and antibacterial activity of silver nanoparticles synthesized by using Taxus wallichiana leaf extract. PeerJ 10:e14391 https://doi.org/10.7717/peerj.14391
date submitted: 2022-06-15
date accepted: 2022-10-23
issued: 2022-11-23
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Yousaf
  given name: Aliya
author list: Agent
  family name: Waseem
  given name: Muhammad
author list: Agent
  family name: Javed
  given name: Aneela
author list: Agent
  family name: Baig
  given name: Sofia
author list: Agent
  family name: Ismail
  given name: Bushra
author list: Agent
  family name: Baig
  given name: Ayesha
author list: Agent
  family name: Shahzadi
  given name: Irum
author list: Agent
  family name: Nawazish
  given name: Shamyla
author list: Agent
  family name: Zaman
  given name: Iftikhar
doi: 10.7717/peerj.14391
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-23
copyright: © 2022 Yousaf et al.
attribution name: Yousaf et al.

Sarcopenia and echocardiographic parameters for prediction of cardiovascular events and mortality in patients undergoing maintenance hemodialysis
type: item
type: AcademicArticle
description: Background Sarcopenia is prevalent and is associated with the occurrence of cardiovascular complications in patients undergoing maintenance hemodialysis (MHD). It is unknown how skeletal muscle may be associated with aspects of myocardial structure and function. This study aimed to evaluate the association between sarcopenia and cardiac structure and function in patients undergoing MHD. We also examined the prognostic role of sarcopenia for mortality and cardiovascular events (CVE) in this population. Methods Participants from a single center underwent bioimpedance body composition analysis to measure skeletal muscle and echocardiography to assess myocardial structure and function. Sarcopenia was diagnosed based on the Asian Working Group for Sarcopenia criteria. The end points were all-cause mortality and CVE. Results Of the 158 participants, 46 (29.1%) had sarcopenia, 102 (64.6%) had left ventricular diastolic dysfunction (LVDD), and 106 (67.0%) had left ventricular hypertrophy (LVH). Participants with sarcopenia had smaller right ventricular sizes (2.54 ± 0.77 vs 2.76 ± 0.28; P < 0.01), inter-ventricular thickness (1.07 ± 0.19 vs 1.14 ± 0.20; P = 0.039), and left ventricular posterior wall thickness (0.96, 0.89–1.10 vs 1.06, 0.95–1.20; P = 0.018). Skeletal muscle mass was strongly correlated with left ventricular mass (LVM) (r = 0.577; P < 0.0001). Furthermore, the risk of LVDD (OR: 4.92, 95% confidence interval (CI) [1.73–13.95]) and LVH (OR: 4.88, 95% CI [1.08–21.96]) was much higher in the sarcopenic group than in the non-sarcopenic group. During a follow-up period of 18 months, 11 (6.9%) patients died, of which seven died (4.4%) of CVE, and 36 (22.8%) experienced CVE. The presence of sarcopenia (adjusted hazard ratio (HR), 6.59; 95% CI [1.08–39.91]; P = 0.041) and low skeletal muscle index (HR, 3.41; 95% CI [1.01–11.57]; P = 0.049) and handgrip strength (HR, 0.88; 95% CI [0.78–0.99]; P = 0.037) independently predicted death. Sarcopenia was a significant predi…
format: application/pdf
format: text/html
creator: Mengyan Zhang
creator: Liuping Zhang
creator: Yezi Hu
creator: Ying Wang
creator: Shengchun Xu
creator: Xiaotong Xie
creator: Tian Xu
creator: Zuolin Li
creator: Hui Jin
creator: Hong Liu
subject: Cardiology
subject: Nephrology
subject: Nutrition
subject: Orthopedics
description: doi:10.7717/peerj.14429
publisher: PeerJ Inc.
rights: © 2022 Zhang et al.
abstract: Background Sarcopenia is prevalent and is associated with the occurrence of cardiovascular complications in patients undergoing maintenance hemodialysis (MHD). It is unknown how skeletal muscle may be associated with aspects of myocardial structure and function. This study aimed to evaluate the association between sarcopenia and cardiac structure and function in patients undergoing MHD. We also examined the prognostic role of sarcopenia for mortality and cardiovascular events (CVE) in this population. Methods Participants from a single center underwent bioimpedance body composition analysis to measure skeletal muscle and echocardiography to assess myocardial structure and function. Sarcopenia was diagnosed based on the Asian Working Group for Sarcopenia criteria. The end points were all-cause mortality and CVE. Results Of the 158 participants, 46 (29.1%) had sarcopenia, 102 (64.6%) had left ventricular diastolic dysfunction (LVDD), and 106 (67.0%) had left ventricular hypertrophy (LVH). Participants with sarcopenia had smaller right ventricular sizes (2.54 ± 0.77 vs 2.76 ± 0.28; P < 0.01), inter-ventricular thickness (1.07 ± 0.19 vs 1.14 ± 0.20; P = 0.039), and left ventricular posterior wall thickness (0.96, 0.89–1.10 vs 1.06, 0.95–1.20; P = 0.018). Skeletal muscle mass was strongly correlated with left ventricular mass (LVM) (r = 0.577; P < 0.0001). Furthermore, the risk of LVDD (OR: 4.92, 95% confidence interval (CI) [1.73–13.95]) and LVH (OR: 4.88, 95% CI [1.08–21.96]) was much higher in the sarcopenic group than in the non-sarcopenic group. During a follow-up period of 18 months, 11 (6.9%) patients died, of which seven died (4.4%) of CVE, and 36 (22.8%) experienced CVE. The presence of sarcopenia (adjusted hazard ratio (HR), 6.59; 95% CI [1.08–39.91]; P = 0.041) and low skeletal muscle index (HR, 3.41; 95% CI [1.01–11.57]; P = 0.049) and handgrip strength (HR, 0.88; 95% CI [0.78–0.99]; P = 0.037) independently predicted death. Sarcopenia was a significant predi…
bibliographic citation: Zhang et al. (2022) Sarcopenia and echocardiographic parameters for prediction of cardiovascular events and mortality in patients undergoing maintenance hemodialysis. PeerJ 10:e14429 https://doi.org/10.7717/peerj.14429
date submitted: 2022-08-16
date accepted: 2022-10-30
issued: 2022-11-23
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Zhang
  given name: Mengyan
author list: Agent
  family name: Zhang
  given name: Liuping
author list: Agent
  family name: Hu
  given name: Yezi
author list: Agent
  family name: Wang
  given name: Ying
author list: Agent
  family name: Xu
  given name: Shengchun
author list: Agent
  family name: Xie
  given name: Xiaotong
author list: Agent
  family name: Xu
  given name: Tian
author list: Agent
  family name: Li
  given name: Zuolin
author list: Agent
  family name: Jin
  given name: Hui
author list: Agent
  family name: Liu
  given name: Hong
doi: 10.7717/peerj.14429
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-23
copyright: © 2022 Zhang et al.
attribution name: Zhang et al.

Co-occurrence of seagrass vegetation and coral colonies supports unique fish assemblages: a microhabitat-scale perspective
type: item
type: AcademicArticle
description: Numerous studies have suggested that seagrass beds provide nursery habitats for juvenile fish in both tropical and subtropical regions. Most of these previous studies applied a landscape-scale perspective, in which seagrass beds and coral reefs are treated as independent, homogenous habitats. However, this perspective might overlook the microhabitat-scale perspective within the habitats, for example, the possibility that small-sized hard substrates (e.g., coral colonies) within seagrass beds might serve as fish nurseries. The present study aimed to examine the effects of the presence of microhabitats (small-sized coral colonies) within seagrass beds on the structure of fish assemblages. Fieldwork was conducted at Urasoko Bay, Ishigaki Island, Okinawa, Japan. Four habitat zones were selected: (1) seagrass bed with presence of massive coral colonies (SGCO), (2) seagrass bed without coral colonies (SG), (3) sandy bottom (without seagrass vegetation) with massive coral colonies (CO), and (4) sandy bottom without seagrass vegetation or coral colonies (SA). Six 20 m × 2 m line transects were established and monthly underwater observations were conducted between June and October in 2018 and 2019. A cluster analysis, analysis of similarity, and principal component analysis revealed that the fish assemblage at SGCO was significantly different from the other three habitat zones. This was because some fish species (e.g., Ostorhinchusishigakiensis and Lutjanus gibbus) were almost exclusively present at SGCO and rarely seen at CO, SG, and SA. Most individual fish belonging to these species were found on coral colonies at SGCO, suggesting that the co-occurrence of seagrass vegetation and coral colonies is essential for the habitats of these fish species. Although other fish species present at SGCO were also found at SG, three species, Parupeneus barberinus, Stethojulis strigiventer, and Lethrinus atkinsoni, were more abundant at SGCO with some found on coral colonies in this habi…
format: application/pdf
format: text/html
creator: Atsushi Nanami
subject: Aquaculture, Fisheries and Fish Science
subject: Biodiversity
subject: Ecology
subject: Marine Biology
subject: Zoology
description: doi:10.7717/peerj.14466
publisher: PeerJ Inc.
rights: © 2022 Nanami
abstract: Numerous studies have suggested that seagrass beds provide nursery habitats for juvenile fish in both tropical and subtropical regions. Most of these previous studies applied a landscape-scale perspective, in which seagrass beds and coral reefs are treated as independent, homogenous habitats. However, this perspective might overlook the microhabitat-scale perspective within the habitats, for example, the possibility that small-sized hard substrates (e.g., coral colonies) within seagrass beds might serve as fish nurseries. The present study aimed to examine the effects of the presence of microhabitats (small-sized coral colonies) within seagrass beds on the structure of fish assemblages. Fieldwork was conducted at Urasoko Bay, Ishigaki Island, Okinawa, Japan. Four habitat zones were selected: (1) seagrass bed with presence of massive coral colonies (SGCO), (2) seagrass bed without coral colonies (SG), (3) sandy bottom (without seagrass vegetation) with massive coral colonies (CO), and (4) sandy bottom without seagrass vegetation or coral colonies (SA). Six 20 m × 2 m line transects were established and monthly underwater observations were conducted between June and October in 2018 and 2019. A cluster analysis, analysis of similarity, and principal component analysis revealed that the fish assemblage at SGCO was significantly different from the other three habitat zones. This was because some fish species (e.g., Ostorhinchusishigakiensis and Lutjanus gibbus) were almost exclusively present at SGCO and rarely seen at CO, SG, and SA. Most individual fish belonging to these species were found on coral colonies at SGCO, suggesting that the co-occurrence of seagrass vegetation and coral colonies is essential for the habitats of these fish species. Although other fish species present at SGCO were also found at SG, three species, Parupeneus barberinus, Stethojulis strigiventer, and Lethrinus atkinsoni, were more abundant at SGCO with some found on coral colonies in this habi…
bibliographic citation: Nanami (2022) Co-occurrence of seagrass vegetation and coral colonies supports unique fish assemblages: a microhabitat-scale perspective. PeerJ 10:e14466 https://doi.org/10.7717/peerj.14466
date submitted: 2022-06-01
date accepted: 2022-11-04
issued: 2022-11-23
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Nanami
  given name: Atsushi
doi: 10.7717/peerj.14466
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-23
copyright: © 2022 Nanami
attribution name: Nanami

Chronic toxicity of shrimp feed added with silver nanoparticles (Argovit-4®) in Litopenaeus vannamei and immune response to white spot syndrome virus infection
type: item
type: AcademicArticle
description: In recent years, the application of silver nanoparticles (AgNPs) as antibacterial compounds has been widely used in human and veterinary medicine. In this work, we investigated the effects of AgNPs (Argovit-4®) as feed additives (feed-AgNPs) on shrimp (Litopenaeus vannamei) using three different methods: 1) chronic toxicity after 28 days of feeding, 2) Effects against white spot syndrome virus (WSSV) challenged by oral route, and 3) transcriptional responses of immune-related genes (PAP, ProPO, CTL-3, Crustin, PEN3, and PEN4) following WSSV infection. The results showed that the feed-AgNPs did not interfere with the growth and survival of shrimp. Also, mild lesions in the hepatopancreas were recorded, proportional to the frequency of the feed-AgNP supply. Challenge test versus WSSV showed that feeding every 7 days with feed-AgNPs reduced mortality, reaching a survival rate of 53%, compared to the survival rates observed in groups fed every 4 days, daily and control groups of feed-AgNPs for the 30%, 10%, and 7% groups, respectively. Feed-AgNPs negatively regulated the expression of PAP, ProPO, and Crustin genes after 28 days of treatment and altered the transcriptional responses of PAP, ProPO, CTL-3, and Crustin after WSSV exposure. The results showed that weekly feeding-AgNPs could partially prevent WSSV infection in shrimp culture. However, whether or not transcriptional responses against pathogens are advantageous remains to be elucidated.
format: application/pdf
format: text/html
creator: Carlos R. Romo Quiñonez
creator: Píndaro Alvarez-Ruiz
creator: Claudio H. Mejía-Ruiz
creator: Nina Bogdanchikova
creator: Alexey Pestryakov
creator: Carina Gamez-Jimenez
creator: Wenceslao Valenzuela-Quiñonez
creator: Magnolia Montoya-Mejía
creator: Eusebio Nava Pérez
subject: Agricultural Science
subject: Aquaculture, Fisheries and Fish Science
subject: Microbiology
subject: Zoology
subject: Ecotoxicology
description: doi:10.7717/peerj.14231
publisher: PeerJ Inc.
rights: © 2022 Romo Quiñonez et al.
abstract: In recent years, the application of silver nanoparticles (AgNPs) as antibacterial compounds has been widely used in human and veterinary medicine. In this work, we investigated the effects of AgNPs (Argovit-4®) as feed additives (feed-AgNPs) on shrimp (Litopenaeus vannamei) using three different methods: 1) chronic toxicity after 28 days of feeding, 2) Effects against white spot syndrome virus (WSSV) challenged by oral route, and 3) transcriptional responses of immune-related genes (PAP, ProPO, CTL-3, Crustin, PEN3, and PEN4) following WSSV infection. The results showed that the feed-AgNPs did not interfere with the growth and survival of shrimp. Also, mild lesions in the hepatopancreas were recorded, proportional to the frequency of the feed-AgNP supply. Challenge test versus WSSV showed that feeding every 7 days with feed-AgNPs reduced mortality, reaching a survival rate of 53%, compared to the survival rates observed in groups fed every 4 days, daily and control groups of feed-AgNPs for the 30%, 10%, and 7% groups, respectively. Feed-AgNPs negatively regulated the expression of PAP, ProPO, and Crustin genes after 28 days of treatment and altered the transcriptional responses of PAP, ProPO, CTL-3, and Crustin after WSSV exposure. The results showed that weekly feeding-AgNPs could partially prevent WSSV infection in shrimp culture. However, whether or not transcriptional responses against pathogens are advantageous remains to be elucidated.
bibliographic citation: Romo Quiñonez et al. (2022) Chronic toxicity of shrimp feed added with silver nanoparticles (Argovit-4®) in Litopenaeus vannamei and immune response to white spot syndrome virus infection. PeerJ 10:e14231 https://doi.org/10.7717/peerj.14231
date submitted: 2022-06-14
date accepted: 2022-09-22
issued: 2022-11-22
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Romo Quiñonez
  given name: Carlos R.
author list: Agent
  family name: Alvarez-Ruiz
  given name: Píndaro
author list: Agent
  family name: Mejía-Ruiz
  given name: Claudio H.
author list: Agent
  family name: Bogdanchikova
  given name: Nina
author list: Agent
  family name: Pestryakov
  given name: Alexey
author list: Agent
  family name: Gamez-Jimenez
  given name: Carina
author list: Agent
  family name: Valenzuela-Quiñonez
  given name: Wenceslao
author list: Agent
  family name: Montoya-Mejía
  given name: Magnolia
author list: Agent
  family name: Nava Pérez
  given name: Eusebio
doi: 10.7717/peerj.14231
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-22
copyright: ©2022 Romo Quiñonez et al.
attribution name: Romo Quiñonez et al.

“Double whammy”: a rapid review of rural vs urban psychosocial cancer experiences and telehealth service in five countries during the COVID-19 pandemic
type: item
type: AcademicArticle
description: Background Cancer is a long-term condition with biopsychosocial components. People with cancer living in rural areas can have poorer treatment outcomes and higher rates of unmet psychosocial needs than those in urban areas. Cancer, as opposed to other chronic conditions, poses a unique challenge in this current COVID-19 pandemic context, given immunocompromised states of patients and long-term survivor treatment effects. The disaggregated impact of psychosocial issues potentiated by the pandemic on rural vs. urban cancer populations is yet to be quantified. This rapid review investigates whether (i) people with cancer are experiencing pandemic-related psychosocial impacts, (ii) these impacts are equivalent in urban and rural locations, and (iii) whether the rapid uptake of telehealth mitigates or reinforces any identified impacts. Method A rapid review was conducted for literature published between December 2019 and 13 August 2021. Results Fifteen papers were included, incorporating evidence from five countries. The available literature suggests people affected by cancer living in rural areas are evidencing disproportionate psychosocial impacts of COVID-19, compounding cancer experiences. Despite its widespread and necessary use during the pandemic, telehealth was identified as an additional challenge for rural people with cancer. Conclusions Clinicians working with rural people affected by cancer should ensure recognition of the greater risks of psychosocial concerns in their rural patients, and reduced access to health services. Whilst telehealth and other remote technologies are useful and necessary in this pandemic era, clinicians should consider whether its use benefits their rural clients or reinforces existing disparities.
format: application/pdf
format: text/html
creator: Marisa Barnes
creator: Kylie Rice
creator: Clara Murray
creator: Einar Thorsteinsson
subject: Global Health
subject: Oncology
subject: Psychiatry and Psychology
subject: Mental Health
subject: Healthcare Services
description: doi:10.7717/peerj.14382
publisher: PeerJ Inc.
rights: © 2022 Barnes et al.
abstract: Background Cancer is a long-term condition with biopsychosocial components. People with cancer living in rural areas can have poorer treatment outcomes and higher rates of unmet psychosocial needs than those in urban areas. Cancer, as opposed to other chronic conditions, poses a unique challenge in this current COVID-19 pandemic context, given immunocompromised states of patients and long-term survivor treatment effects. The disaggregated impact of psychosocial issues potentiated by the pandemic on rural vs. urban cancer populations is yet to be quantified. This rapid review investigates whether (i) people with cancer are experiencing pandemic-related psychosocial impacts, (ii) these impacts are equivalent in urban and rural locations, and (iii) whether the rapid uptake of telehealth mitigates or reinforces any identified impacts. Method A rapid review was conducted for literature published between December 2019 and 13 August 2021. Results Fifteen papers were included, incorporating evidence from five countries. The available literature suggests people affected by cancer living in rural areas are evidencing disproportionate psychosocial impacts of COVID-19, compounding cancer experiences. Despite its widespread and necessary use during the pandemic, telehealth was identified as an additional challenge for rural people with cancer. Conclusions Clinicians working with rural people affected by cancer should ensure recognition of the greater risks of psychosocial concerns in their rural patients, and reduced access to health services. Whilst telehealth and other remote technologies are useful and necessary in this pandemic era, clinicians should consider whether its use benefits their rural clients or reinforces existing disparities.
bibliographic citation: Barnes et al. (2022) “Double whammy”: a rapid review of rural vs urban psychosocial cancer experiences and telehealth service in five countries during the COVID-19 pandemic. PeerJ 10:e14382 https://doi.org/10.7717/peerj.14382
date submitted: 2022-08-31
date accepted: 2022-10-21
issued: 2022-11-22
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Barnes
  given name: Marisa
author list: Agent
  family name: Rice
  given name: Kylie
author list: Agent
  family name: Murray
  given name: Clara
author list: Agent
  family name: Thorsteinsson
  given name: Einar
doi: 10.7717/peerj.14382
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-22
copyright: © 2022 Barnes et al.
attribution name: Barnes et al.

The effects of Saccharomyces boulardii on rat colonic hypermotility induced by repeated water avoidance stress and the potential mechanism
type: item
type: AcademicArticle
description: Background Saccharomyces boulardii (Sb) has been reported to have the potential to regulate gut motility. The aim of this experiment was to explore the possible function of Sb in gut hypermotility elicited by repeated water avoidance stress (WAS). Methods Adult male Wistar rats (N = 24) were divided into one of the following three groups: control (C), NS (normal saline) + WAS group (N), and Sb + WAS group (S). A diarrhea-predominant irritable bowel syndrome (IBS-D) model in rats was induced using the WAS method. Gut motility was evaluated by stool pellet expulsion per hour. The contractile activity of the colonic muscle strips was measured using an RM6240 multichannel physiological signal instrument. qRT-PCR and immunohistochemistry were used to assess Toll-like receptor 4 (TLR4) expression in colon tissue. ELISA was used to measure the level of cytokines in the serum and colonic tissue. Also, the microbiota composition was determined using high-throughput 16S rRNA sequencing. Result The results showed that oral Sb decreased the WAS-induced increased defecation and colonic hypermotility in vivo. Furthermore, Sb also decreased the contractile amplitude of colonic circular muscle (CM) and longitudinal muscle (LM) strips in a dose-dependent manner in vitro. Repeated WAS increased TLR4 expression, but Sb reversed it. Sb also reduced interleukin-6 (IL-6), IL-1β, and interferon-γ (IFN-γ) levels in serum and colonic tissue, while increasing IL-10 levels in colonic tissue. Meanwhile, the rats from the NS + WAS group had decreased microbiota diversity and had lower relative abundances of Patescibacteria, Epsilonbacteraeota, Cyanobacteria, and Turicibacter compared with controls. The rats in the Sb + WAS group showed a tendency to increase the relative abundance of Blautia when compared to control rats and had lower relative abundances of Acidobacteria and Anaerostipes compared with the NS + WAS group. Conclusion Our findings demonstrated that Sb improved colonic hypermotilit…
format: application/pdf
format: text/html
creator: Jingwen Liu
creator: Haixia Ren
creator: Fangting Yuan
creator: Ming Shao
creator: Hesheng Luo
subject: Gastroenterology and Hepatology
subject: Nutrition
description: doi:10.7717/peerj.14390
publisher: PeerJ Inc.
rights: © 2022 Liu et al.
abstract: Background Saccharomyces boulardii (Sb) has been reported to have the potential to regulate gut motility. The aim of this experiment was to explore the possible function of Sb in gut hypermotility elicited by repeated water avoidance stress (WAS). Methods Adult male Wistar rats (N = 24) were divided into one of the following three groups: control (C), NS (normal saline) + WAS group (N), and Sb + WAS group (S). A diarrhea-predominant irritable bowel syndrome (IBS-D) model in rats was induced using the WAS method. Gut motility was evaluated by stool pellet expulsion per hour. The contractile activity of the colonic muscle strips was measured using an RM6240 multichannel physiological signal instrument. qRT-PCR and immunohistochemistry were used to assess Toll-like receptor 4 (TLR4) expression in colon tissue. ELISA was used to measure the level of cytokines in the serum and colonic tissue. Also, the microbiota composition was determined using high-throughput 16S rRNA sequencing. Result The results showed that oral Sb decreased the WAS-induced increased defecation and colonic hypermotility in vivo. Furthermore, Sb also decreased the contractile amplitude of colonic circular muscle (CM) and longitudinal muscle (LM) strips in a dose-dependent manner in vitro. Repeated WAS increased TLR4 expression, but Sb reversed it. Sb also reduced interleukin-6 (IL-6), IL-1β, and interferon-γ (IFN-γ) levels in serum and colonic tissue, while increasing IL-10 levels in colonic tissue. Meanwhile, the rats from the NS + WAS group had decreased microbiota diversity and had lower relative abundances of Patescibacteria, Epsilonbacteraeota, Cyanobacteria, and Turicibacter compared with controls. The rats in the Sb + WAS group showed a tendency to increase the relative abundance of Blautia when compared to control rats and had lower relative abundances of Acidobacteria and Anaerostipes compared with the NS + WAS group. Conclusion Our findings demonstrated that Sb improved colonic hypermotilit…
bibliographic citation: Liu et al. (2022) The effects of Saccharomyces boulardii on rat colonic hypermotility induced by repeated water avoidance stress and the potential mechanism. PeerJ 10:e14390 https://doi.org/10.7717/peerj.14390
date submitted: 2022-07-06
date accepted: 2022-10-23
issued: 2022-11-22
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Liu
  given name: Jingwen
author list: Agent
  family name: Ren
  given name: Haixia
author list: Agent
  family name: Yuan
  given name: Fangting
author list: Agent
  family name: Shao
  given name: Ming
author list: Agent
  family name: Luo
  given name: Hesheng
doi: 10.7717/peerj.14390
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-22
copyright: ©2022 Liu et al.
attribution name: Liu et al.

Adjuvant chemoradiotherapy versus chemotherapy or radiotherapy in advanced endometrial cancer: a systematic review and meta-analysis
type: item
type: AcademicArticle
description: Background Endometrial cancer is one of the most common gynecological cancer in the world. However, the available adjuvant therapies, chemotherapy (CT) and radiotherapy (RT), demonstrated several limitations when used alone. Therefore, we conducted a meta-analysis to investigate the clinical effectiveness of chemoradiotherapy (CRT) based on overall survival (OS) and disease-free survival (DFS). Methods A literature search was performed on five databases and one clinical trial registry to obtain all relevant articles. Search for studies was completed on September 9, 2021. A meta-analysis was conducted to determine the overall hazard ratio with the 95% Confidence Interval. Results A total of 17 articles with 23,975 patients in the CRT vs RT group and 50,502 patients in the CRT vs CT group were included. The OS Hazard Ratios (HR) of CRT compared to RT was 0.66 (95% CI [0.59–0.75]; P < 0.00001). Compared to CT, the OS HR was 0.70 (95% CI [0.64–0.78]; P < 0.00001). CRT also significantly improved the DFS compared to CT only (HR 0.79, 95% CI [0.64–0.97]; P = 0.02) However, CRT did not improve the DFS compared to RT only, with HR of 0.71 (95% CI [0.46–1.09]; P = 0.12). Conclusion Adjuvant CRT can significantly improve OS compared to CT or RT alone and improve the DFS compared to CT alone in patients with advanced endometrial cancer. Further research is needed to identify the optimal CRT regimen, and to whom CRT will be most beneficial.
format: application/pdf
format: text/html
creator: Hariyono Winarto
creator: Naufal A. A. Ibrahim
creator: Yan M. Putri
creator: Faiqueen D. S. F. Adnan
creator: Eka D. Safitri
subject: Clinical Trials
subject: Drugs and Devices
subject: Gynecology and Obstetrics
subject: Oncology
subject: Women’s Health
description: doi:10.7717/peerj.14420
publisher: PeerJ Inc.
rights: © 2022 Winarto et al.
abstract: Background Endometrial cancer is one of the most common gynecological cancer in the world. However, the available adjuvant therapies, chemotherapy (CT) and radiotherapy (RT), demonstrated several limitations when used alone. Therefore, we conducted a meta-analysis to investigate the clinical effectiveness of chemoradiotherapy (CRT) based on overall survival (OS) and disease-free survival (DFS). Methods A literature search was performed on five databases and one clinical trial registry to obtain all relevant articles. Search for studies was completed on September 9, 2021. A meta-analysis was conducted to determine the overall hazard ratio with the 95% Confidence Interval. Results A total of 17 articles with 23,975 patients in the CRT vs RT group and 50,502 patients in the CRT vs CT group were included. The OS Hazard Ratios (HR) of CRT compared to RT was 0.66 (95% CI [0.59–0.75]; P < 0.00001). Compared to CT, the OS HR was 0.70 (95% CI [0.64–0.78]; P < 0.00001). CRT also significantly improved the DFS compared to CT only (HR 0.79, 95% CI [0.64–0.97]; P = 0.02) However, CRT did not improve the DFS compared to RT only, with HR of 0.71 (95% CI [0.46–1.09]; P = 0.12). Conclusion Adjuvant CRT can significantly improve OS compared to CT or RT alone and improve the DFS compared to CT alone in patients with advanced endometrial cancer. Further research is needed to identify the optimal CRT regimen, and to whom CRT will be most beneficial.
bibliographic citation: Winarto et al. (2022) Adjuvant chemoradiotherapy versus chemotherapy or radiotherapy in advanced endometrial cancer: a systematic review and meta-analysis. PeerJ 10:e14420 https://doi.org/10.7717/peerj.14420
date submitted: 2022-07-25
date accepted: 2022-10-28
issued: 2022-11-22
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Winarto
  given name: Hariyono
author list: Agent
  family name: Ibrahim
  given name: Naufal A. A.
author list: Agent
  family name: Putri
  given name: Yan M.
author list: Agent
  family name: Adnan
  given name: Faiqueen D. S. F.
author list: Agent
  family name: Safitri
  given name: Eka D.
doi: 10.7717/peerj.14420
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-22
copyright: © 2022 Winarto et al.
attribution name: Winarto et al.

A new species and new records species of Pluteus from Xinjiang Uygur Autonomous Region, China
type: item
type: AcademicArticle
description: Xinjiang Uyghur Autonomous Region in China embraces a unique geographical and ecological environment, and the macrofungi represent a rich resource. However, few studies on the genus Pluteus have been reported from Xinjiang. In 2021, the macrofungal resources in Xinjiang were surveyed, and 10 specimens belonging to the genus Pluteus were collected. Based on the morphological study and molecular analysis, three species were recognized, P. aletaiensis, P. brunneidiscus, and P. hongoi. Pluteus aletaiensis is proposed as a new species. It is characterized by its bright yellow lamellae and stipe, brittle texture, subfusiform to vesicular pleurocystidia, with short pedicels to broadly lageniform to obtuse at apices, a hymeniderm pileipellis, containing dark brown intracellular pigment, and it grows on the ground. Pluteus brunneidiscus, a new record to China, is characterized by uneven, smooth, grayish brown to brown pileus, with an entire margin, and pointed or flatter apices intermediate cystidia, without apical hooks. Pluteus hongoi, a new record to Xinjiang Uyghur Autonomous Region, China, is characterized by the apical hook’s structure (commonly bifid) of pleurocystidia. The nuclear internal transcribed spacer (nrITS) and translation elongation factor 1-alpha (TEF1-a) region were used for the molecular analysis. Phylogenetic trees were constructed using both the maximum likelihood analysis (ML) and Bayesian inference (BI). Detailed descriptions of the three species are presented herein. Finally, a key to the list of eight species of the genus Pluteus knew from Xinjiang is provided.
format: application/pdf
format: text/html
creator: Zheng-xiang Qi
creator: Ke-qing Qian
creator: Jia-jun Hu
creator: Yang Wang
creator: Dong-mei Wu
creator: Neng Gao
creator: Pei-Song Jia
creator: Zhen-hao Zhang
creator: Bo Zhang
creator: Yu Li
subject: Biodiversity
subject: Molecular Biology
subject: Mycology
subject: Taxonomy
description: doi:10.7717/peerj.14298
publisher: PeerJ Inc.
rights: © 2022 Qi et al.
abstract: Xinjiang Uyghur Autonomous Region in China embraces a unique geographical and ecological environment, and the macrofungi represent a rich resource. However, few studies on the genus Pluteus have been reported from Xinjiang. In 2021, the macrofungal resources in Xinjiang were surveyed, and 10 specimens belonging to the genus Pluteus were collected. Based on the morphological study and molecular analysis, three species were recognized, P. aletaiensis, P. brunneidiscus, and P. hongoi. Pluteus aletaiensis is proposed as a new species. It is characterized by its bright yellow lamellae and stipe, brittle texture, subfusiform to vesicular pleurocystidia, with short pedicels to broadly lageniform to obtuse at apices, a hymeniderm pileipellis, containing dark brown intracellular pigment, and it grows on the ground. Pluteus brunneidiscus, a new record to China, is characterized by uneven, smooth, grayish brown to brown pileus, with an entire margin, and pointed or flatter apices intermediate cystidia, without apical hooks. Pluteus hongoi, a new record to Xinjiang Uyghur Autonomous Region, China, is characterized by the apical hook’s structure (commonly bifid) of pleurocystidia. The nuclear internal transcribed spacer (nrITS) and translation elongation factor 1-alpha (TEF1-a) region were used for the molecular analysis. Phylogenetic trees were constructed using both the maximum likelihood analysis (ML) and Bayesian inference (BI). Detailed descriptions of the three species are presented herein. Finally, a key to the list of eight species of the genus Pluteus knew from Xinjiang is provided.
bibliographic citation: Qi et al. (2022) A new species and new records species of Pluteus from Xinjiang Uygur Autonomous Region, China. PeerJ 10:e14298 https://doi.org/10.7717/peerj.14298
date submitted: 2022-03-23
date accepted: 2022-10-04
issued: 2022-11-21
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Qi
  given name: Zheng-xiang
author list: Agent
  family name: Qian
  given name: Ke-qing
author list: Agent
  family name: Hu
  given name: Jia-jun
author list: Agent
  family name: Wang
  given name: Yang
author list: Agent
  family name: Wu
  given name: Dong-mei
author list: Agent
  family name: Gao
  given name: Neng
author list: Agent
  family name: Jia
  given name: Pei-Song
author list: Agent
  family name: Zhang
  given name: Zhen-hao
author list: Agent
  family name: Zhang
  given name: Bo
author list: Agent
  family name: Li
  given name: Yu
doi: 10.7717/peerj.14298
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-21
copyright: © 2022 Qi et al.
attribution name: Qi et al.

The triglycerides-glucose index and the triglycerides to high-density lipoprotein cholesterol ratio are both effective predictors of in-hospital death in non-diabetic patients with AMI
type: item
type: AcademicArticle
description: Background The triglycerides-glucose index (TyG) and the triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) are simple indicators for assessing insulin resistance in epidemiological studies. We aimed to clarify the relationship between indicators of insulin resistance and prognosis in non-diabetic acute myocardial infarction (AMI) patients. Methods A total of 1,648 AMI patients without diabetes were enrolled from the Department of Cardiology, Zhongda Hospital, between 2012.03 and 2018.12. The medical history, laboratory and imaging data of patients were collected through the medical record system, and all-cause death events were recorded. Pearson analysis was used to study the correlation among different variables. Logistic regression analysis was used to analyze the predictive effect of TyG and TG/HDL-C in in-hospital death of AMI patients. Results 1. In AMI group, the TyG index was significantly increased in death groups compared to no-death groups (P = 0.025). TG/HDL-C was not significantly increased in the death group of AMI patients (P = 0.588). The patients were respectively divided into Q1-Q4 groups and T1-T4 groups according to the quartiles of TyG and TG/HDL-C. The trends of in-hospital mortality in the Q4 group of TyG and T4 group of TG/HDL-C were higher than in other groups, although these differences were not significant. 2. Pearson correlation analysis showed that TyG was positively correlated with lipid-related markers, including ApoB (r = 0.248, P < 0.001), total cholesterol (TC) (r = 0.270, P < 0.001), low-density lipoprotein cholesterol (LDL-C) (r = 0.238, P < 0.001). Spearman analysis showed that TG/HDL-C was also positively associated with TC (r = 0.107, P < 0.001), ApoB (r = 0.180, P < 0.001) and LDL-C (r = 0.164, P < 0.001). 3. Logistic regression analysis showed that TyG (OR = 3.106, 95% CI [2.122–4.547], P < 0.001) and TG/HDL-C (OR = 1.167, 95% CI [1.062–1.282], P = 0.001) were both important factors to predict the in-hospital de…
format: application/pdf
format: text/html
creator: Jiaqi Guo
creator: Zhenjun Ji
creator: Abdlay Carvalho
creator: Linglin Qian
creator: Jingjing Ji
creator: Yu Jiang
creator: Guiren Liu
creator: Genshan Ma
creator: Yuyu Yao
subject: Cardiology
subject: Internal Medicine
description: doi:10.7717/peerj.14346
publisher: PeerJ Inc.
rights: © 2022 Guo et al.
abstract: Background The triglycerides-glucose index (TyG) and the triglycerides to high-density lipoprotein cholesterol (TG/HDL-C) are simple indicators for assessing insulin resistance in epidemiological studies. We aimed to clarify the relationship between indicators of insulin resistance and prognosis in non-diabetic acute myocardial infarction (AMI) patients. Methods A total of 1,648 AMI patients without diabetes were enrolled from the Department of Cardiology, Zhongda Hospital, between 2012.03 and 2018.12. The medical history, laboratory and imaging data of patients were collected through the medical record system, and all-cause death events were recorded. Pearson analysis was used to study the correlation among different variables. Logistic regression analysis was used to analyze the predictive effect of TyG and TG/HDL-C in in-hospital death of AMI patients. Results 1. In AMI group, the TyG index was significantly increased in death groups compared to no-death groups (P = 0.025). TG/HDL-C was not significantly increased in the death group of AMI patients (P = 0.588). The patients were respectively divided into Q1-Q4 groups and T1-T4 groups according to the quartiles of TyG and TG/HDL-C. The trends of in-hospital mortality in the Q4 group of TyG and T4 group of TG/HDL-C were higher than in other groups, although these differences were not significant. 2. Pearson correlation analysis showed that TyG was positively correlated with lipid-related markers, including ApoB (r = 0.248, P < 0.001), total cholesterol (TC) (r = 0.270, P < 0.001), low-density lipoprotein cholesterol (LDL-C) (r = 0.238, P < 0.001). Spearman analysis showed that TG/HDL-C was also positively associated with TC (r = 0.107, P < 0.001), ApoB (r = 0.180, P < 0.001) and LDL-C (r = 0.164, P < 0.001). 3. Logistic regression analysis showed that TyG (OR = 3.106, 95% CI [2.122–4.547], P < 0.001) and TG/HDL-C (OR = 1.167, 95% CI [1.062–1.282], P = 0.001) were both important factors to predict the in-hospital de…
bibliographic citation: Guo et al. (2022) The triglycerides-glucose index and the triglycerides to high-density lipoprotein cholesterol ratio are both effective predictors of in-hospital death in non-diabetic patients with AMI. PeerJ 10:e14346 https://doi.org/10.7717/peerj.14346
date submitted: 2022-06-20
date accepted: 2022-10-16
issued: 2022-11-21
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Guo
  given name: Jiaqi
author list: Agent
  family name: Ji
  given name: Zhenjun
author list: Agent
  family name: Carvalho
  given name: Abdlay
author list: Agent
  family name: Qian
  given name: Linglin
author list: Agent
  family name: Ji
  given name: Jingjing
author list: Agent
  family name: Jiang
  given name: Yu
author list: Agent
  family name: Liu
  given name: Guiren
author list: Agent
  family name: Ma
  given name: Genshan
author list: Agent
  family name: Yao
  given name: Yuyu
doi: 10.7717/peerj.14346
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-21
copyright: ©2022 Guo et al.
attribution name: Guo et al.

Reliability of kettlebell swing one and five repetition maximum
type: item
type: AcademicArticle
description: Background Research into the kettlebell swing has increased in the last decade. There has been a paucity of literature assessing an individual’s ability to perform the kettlebell swing exercise. The purpose of this study was to determine the test-retest reliability of the one and five repetition maximum (1RM and 5RM) kettlebell swing. Materials & Methods Twenty four recreational resistance-trained participants performed an isometric mid-thigh pull (IMTP) and two familiarization sessions followed by three test sessions for each RM load approximately one week apart, using a custom-built plate-loaded kettlebell. On each test occasion, subjects completed a series of warm-up sets followed by 3–4 progressively heavier kettlebell swings to a standardized height until 1RM or 5RM was reached. Test-retest reliability was calculated using the intra-class correlation (ICC) and typical error was represented as the coefficient of variation (CV%) with 90% confidence limits (90% CL). The smallest worthwhile change (SWC%) representing the smallest change of practical importance, was calculated as 0.2 × between-subject standard deviation. The relationship of kettlebell swing performance and maximum strength was determined by Pearson correlation with ±90% CL between the absolute peak force recorded during IMTP and 1RM or 5RM. Results Results demonstrated a high test-retest reliability for both the 1RM (ICC = 0.97, 90% CL [0.95–0.99]; CV = 2.7%, 90% CL [2.2–3.7%]) and 5RM (ICC = 0.98, 90% CL [0.96–0.99]; CV = 2.4%, 90% CL [1.9–3.3%]), respectively. The CV% was lower than the SWC for both the 1RM (SWC = 2.8%, 90% CL [1.9–3.5]) and 5RM (SWC = 2.9%, 90% CL [1.9–3.6]) kettlebell swing. The correlation between IMTP absolute peak force and the 1RM (r = 0.69, 90% CL 0.43–0.83) was large and very large for the 5RM (r = 0.75, 90% CL [0.55–0.87]). Conclusions These results demonstrate the stability of 1RM and 5RM kettlebell swing performance after two familiarization sessions. Practitioners can …
format: application/pdf
format: text/html
creator: James A. Ross
creator: Justin W. L. Keogh
creator: Christian Lorenzen
subject: Kinesiology
subject: Biomechanics
subject: Sports Medicine
description: doi:10.7717/peerj.14370
publisher: PeerJ Inc.
rights: © 2022 Ross et al.
abstract: Background Research into the kettlebell swing has increased in the last decade. There has been a paucity of literature assessing an individual’s ability to perform the kettlebell swing exercise. The purpose of this study was to determine the test-retest reliability of the one and five repetition maximum (1RM and 5RM) kettlebell swing. Materials & Methods Twenty four recreational resistance-trained participants performed an isometric mid-thigh pull (IMTP) and two familiarization sessions followed by three test sessions for each RM load approximately one week apart, using a custom-built plate-loaded kettlebell. On each test occasion, subjects completed a series of warm-up sets followed by 3–4 progressively heavier kettlebell swings to a standardized height until 1RM or 5RM was reached. Test-retest reliability was calculated using the intra-class correlation (ICC) and typical error was represented as the coefficient of variation (CV%) with 90% confidence limits (90% CL). The smallest worthwhile change (SWC%) representing the smallest change of practical importance, was calculated as 0.2 × between-subject standard deviation. The relationship of kettlebell swing performance and maximum strength was determined by Pearson correlation with ±90% CL between the absolute peak force recorded during IMTP and 1RM or 5RM. Results Results demonstrated a high test-retest reliability for both the 1RM (ICC = 0.97, 90% CL [0.95–0.99]; CV = 2.7%, 90% CL [2.2–3.7%]) and 5RM (ICC = 0.98, 90% CL [0.96–0.99]; CV = 2.4%, 90% CL [1.9–3.3%]), respectively. The CV% was lower than the SWC for both the 1RM (SWC = 2.8%, 90% CL [1.9–3.5]) and 5RM (SWC = 2.9%, 90% CL [1.9–3.6]) kettlebell swing. The correlation between IMTP absolute peak force and the 1RM (r = 0.69, 90% CL 0.43–0.83) was large and very large for the 5RM (r = 0.75, 90% CL [0.55–0.87]). Conclusions These results demonstrate the stability of 1RM and 5RM kettlebell swing performance after two familiarization sessions. Practitioners can …
bibliographic citation: Ross et al. (2022) Reliability of kettlebell swing one and five repetition maximum. PeerJ 10:e14370 https://doi.org/10.7717/peerj.14370
date submitted: 2022-07-08
date accepted: 2022-10-19
issued: 2022-11-21
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Ross
  given name: James A.
author list: Agent
  family name: Keogh
  given name: Justin W. L.
author list: Agent
  family name: Lorenzen
  given name: Christian
doi: 10.7717/peerj.14370
volume: 10
issn: 2167-8359
publication name: PeerJ
publication date: 2022-11-21
copyright: © 2022 Ross et al.
attribution name: Ross et al.

PeerJ
type: Periodical
uri: PeerJ
issn: 2167-8359