PeerJ
type: channel
link: https://peerj.com/articles/
description: Articles published in PeerJ
publisher: PeerJ Inc.
publication name: PeerJ
issn: 2167-8359
items: Epidemiology and management of Fusarium wilt of Eucalyptus camaldulensis through systemic acquired resistance
items: The relationship between appearance anxiety and depression among students in a medical university in China: a serial multiple mediation model
items: Adaptation and potential culture of wild Amphipods and Mysids as potential live feed in aquaculture: a review
items: The role of sirtuin1 in liver injury: molecular mechanisms and novel therapeutic target
items: Identifying app components that promote physical activity: a group concept mapping study
items: The effect of complex contrast training with different training frequency on the physical performance of youth soccer players: a randomized study
items: Expression profiles and gene set enrichment analysis of the transcriptomes from the cancer tissue, white adipose tissue and paracancer tissue with colorectal cancer
items: In the social amoeba Dictyostelium discoideum, shortened stalks may limit obligate cheater success even when exploitable partners are available
items: Bayesian estimation of the measurement of interactions in epidemiological studies
items: Predicting the current fishable habitat distribution of Antarctic toothfish (Dissostichus mawsoni) and its shift in the future under climate change in the Southern Ocean

Epidemiology and management of Fusarium wilt of Eucalyptus camaldulensis through systemic acquired resistance
type: item
type: AcademicArticle
description: Eucalyptus camaldulensis is a multifunctional tree and is globally used for the reclamation of problematic lands. Eucalyptus camaldulensis is prone to attack by a number of pathogens, but the most important threat is the Fusarium wilt (Fusarium oxysporum). Keeping in view the importance of E. camaldulensis and to manage this disease, five plant activators, i.e., salicylic acid (C7H6O3), benzoic acid (C7H6O2), citric acid (C6H8O7), dipotassium phosphate (K2HPO4), monopotassium phosphate (KH2PO4) and nutritional mixture namely Compound (NPK) and nutriotop (Fe, Zn, Cu, B, Mn) were evaluated in the Fusarium infested field under RCBD in the Research Area, Department of Forestry and Range Management, University of Agriculture, Faisalabad (UAF). Among plant activators, salicylic acid and a combination of compound + nutriotop exhibited the lowest disease incidence and enhanced fresh and dry weight of leaves compared to other treatments and control. Results of the environmental study indicated maximum disease incidence between 35–40 °C (max. T), 6–25 °C (mini. T), 70–80% relative humidity and 1.5–2.5 km/h wind speed while pan evaporation expressed weak correlation with disease development. It was concluded that Fusarium wilt of Eucalyptus camaldulensis could be managed through activation of the basal defense system of the host plant with provision of salicylic acid and balanced nutrition by considering environmental factors. Recent exploration is expected to be helpful for future research efforts on epidemiology and ecologically sound intervention of Fusarium wilt of Eucalyptus camaldulensis.
format: application/pdf
format: text/html
creator: Irfan Ahmad
creator: Komal Mazhar
creator: Muhammad Atiq
creator: Amna Kahtan Khalaf
creator: Muhammad Haroon U. Rashid
creator: Muhammad Asif
creator: Salman Ahmed
creator: Zoha Adil
creator: Amna Fayyaz
creator: Mohammad Khalid Al-Sadoon
creator: Hamad S. Al-Otaibi
subject: Environmental Contamination and Remediation
subject: Environmental Impacts
subject: Forestry
description: doi:10.7717/peerj.17022
publisher: PeerJ Inc.
rights: © 2024 Ahmad et al.
abstract: Eucalyptus camaldulensis is a multifunctional tree and is globally used for the reclamation of problematic lands. Eucalyptus camaldulensis is prone to attack by a number of pathogens, but the most important threat is the Fusarium wilt (Fusarium oxysporum). Keeping in view the importance of E. camaldulensis and to manage this disease, five plant activators, i.e., salicylic acid (C7H6O3), benzoic acid (C7H6O2), citric acid (C6H8O7), dipotassium phosphate (K2HPO4), monopotassium phosphate (KH2PO4) and nutritional mixture namely Compound (NPK) and nutriotop (Fe, Zn, Cu, B, Mn) were evaluated in the Fusarium infested field under RCBD in the Research Area, Department of Forestry and Range Management, University of Agriculture, Faisalabad (UAF). Among plant activators, salicylic acid and a combination of compound + nutriotop exhibited the lowest disease incidence and enhanced fresh and dry weight of leaves compared to other treatments and control. Results of the environmental study indicated maximum disease incidence between 35–40 °C (max. T), 6–25 °C (mini. T), 70–80% relative humidity and 1.5–2.5 km/h wind speed while pan evaporation expressed weak correlation with disease development. It was concluded that Fusarium wilt of Eucalyptus camaldulensis could be managed through activation of the basal defense system of the host plant with provision of salicylic acid and balanced nutrition by considering environmental factors. Recent exploration is expected to be helpful for future research efforts on epidemiology and ecologically sound intervention of Fusarium wilt of Eucalyptus camaldulensis.
bibliographic citation: Ahmad et al. (2024) Epidemiology and management of Fusarium wilt of Eucalyptus camaldulensis through systemic acquired resistance. PeerJ 12:e17022 https://doi.org/10.7717/peerj.17022
date submitted: 2023-09-05
date accepted: 2024-02-06
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Ahmad
  given name: Irfan
author list: Agent
  family name: Mazhar
  given name: Komal
author list: Agent
  family name: Atiq
  given name: Muhammad
author list: Agent
  family name: Khalaf
  given name: Amna Kahtan
author list: Agent
  family name: Rashid
  given name: Muhammad Haroon U.
author list: Agent
  family name: Asif
  given name: Muhammad
author list: Agent
  family name: Ahmed
  given name: Salman
author list: Agent
  family name: Adil
  given name: Zoha
author list: Agent
  family name: Fayyaz
  given name: Amna
author list: Agent
  family name: Al-Sadoon
  given name: Mohammad Khalid
author list: Agent
  family name: Al-Otaibi
  given name: Hamad S.
doi: 10.7717/peerj.17022
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: © 2024 Ahmad et al.
attribution name: Ahmad et al.

The relationship between appearance anxiety and depression among students in a medical university in China: a serial multiple mediation model
type: item
type: AcademicArticle
description: Background Appearance anxiety and depression have become common and global public health problems worldwide, especially among adolescents. However, few studies have revealed the mechanisms between them. This study aimed to explore the multiple mediating roles of interpersonal sensitivity and social support between appearance anxiety and depression among medical college students. Methods With 13 invalid samples excluded, 724 college students participated in our survey and completed questionnaires. The average age of 724 samples was 19.8 ± 2.02 including freshman to senior year and graduate school and above; 31.9% of the participants were male and 68.1% were female. SPSS 25.0 and Hayes’ PROCESS macro were used for statistical description, correlation analysis and built multiple mediation models. Results Appearance anxiety can not only directly affect depression, but also indirectly affect depression through three significant mediating pathways: (1) IS (B = 0.106, 95% CI [0.082–0.132]), which accounted for 49.77% of the total effect, (2) SS (B = 0.018, 95% CI [0.008–0.031]), which accounted for 8.45% of the total effect, and (3) IS and SS (B = 0.008, 95% CI [0.003–0.014]), which accounted for 3.76% of the total effect. And the total mediating effect was 61.97%. Limitations It is a cross-sectional research method and the causal relationship is unclear. Conclusions This study found that lower interpersonal sensitivity and higher social support can effectively reduce depression caused by appearance anxiety among college students. The schools and relevant departments should take measures to reduce the interpersonal sensitivity of college students and establish reliable social support, so as to reduce the occurrence of depression.
format: application/pdf
format: text/html
creator: Xiaobing Xian
creator: Tengfei Niu
creator: Yu Zhang
creator: Xilin Zhou
creator: Xinxin Wang
creator: Xin Du
creator: Linhan Qu
creator: Binyi Mao
creator: Ying He
creator: Xiyu Chen
creator: Mengliang Ye
subject: Psychiatry and Psychology
subject: Public Health
subject: Mental Health
description: doi:10.7717/peerj.17090
publisher: PeerJ Inc.
rights: © 2024 Xian et al.
abstract: Background Appearance anxiety and depression have become common and global public health problems worldwide, especially among adolescents. However, few studies have revealed the mechanisms between them. This study aimed to explore the multiple mediating roles of interpersonal sensitivity and social support between appearance anxiety and depression among medical college students. Methods With 13 invalid samples excluded, 724 college students participated in our survey and completed questionnaires. The average age of 724 samples was 19.8 ± 2.02 including freshman to senior year and graduate school and above; 31.9% of the participants were male and 68.1% were female. SPSS 25.0 and Hayes’ PROCESS macro were used for statistical description, correlation analysis and built multiple mediation models. Results Appearance anxiety can not only directly affect depression, but also indirectly affect depression through three significant mediating pathways: (1) IS (B = 0.106, 95% CI [0.082–0.132]), which accounted for 49.77% of the total effect, (2) SS (B = 0.018, 95% CI [0.008–0.031]), which accounted for 8.45% of the total effect, and (3) IS and SS (B = 0.008, 95% CI [0.003–0.014]), which accounted for 3.76% of the total effect. And the total mediating effect was 61.97%. Limitations It is a cross-sectional research method and the causal relationship is unclear. Conclusions This study found that lower interpersonal sensitivity and higher social support can effectively reduce depression caused by appearance anxiety among college students. The schools and relevant departments should take measures to reduce the interpersonal sensitivity of college students and establish reliable social support, so as to reduce the occurrence of depression.
bibliographic citation: Xian et al. (2024) The relationship between appearance anxiety and depression among students in a medical university in China: a serial multiple mediation model. PeerJ 12:e17090 https://doi.org/10.7717/peerj.17090
date submitted: 2023-07-26
date accepted: 2024-02-20
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Xian
  given name: Xiaobing
author list: Agent
  family name: Niu
  given name: Tengfei
author list: Agent
  family name: Zhang
  given name: Yu
author list: Agent
  family name: Zhou
  given name: Xilin
author list: Agent
  family name: Wang
  given name: Xinxin
author list: Agent
  family name: Du
  given name: Xin
author list: Agent
  family name: Qu
  given name: Linhan
author list: Agent
  family name: Mao
  given name: Binyi
author list: Agent
  family name: He
  given name: Ying
author list: Agent
  family name: Chen
  given name: Xiyu
author list: Agent
  family name: Ye
  given name: Mengliang
doi: 10.7717/peerj.17090
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: © 2024 Xian et al.
attribution name: Xian et al.

Adaptation and potential culture of wild Amphipods and Mysids as potential live feed in aquaculture: a review
type: item
type: AcademicArticle
description: Live foods such as phytoplankton and zooplankton are essential food sources in aquaculture. Due to their small size, they are suitable for newly hatched larvae. Artemia and rotifer are commonly used live feeds in aquaculture; each feed has a limited dietary value, which is unsuitable for all cultured species. Whereas, copepod and cladocerans species exhibit favorable characteristics that make them viable candidates as sources of essential nutrients for hatchery operations. Due to their jerking movements, it stimulates the feeding response of fish larvae, and their various sizes make them suitable for any fish and crustacean. Even though Artemia is the best live feed due to its proficient nutritional quality, the cost is very expensive, which is about half of the production cost. A recent study suggests the use of amphipods and mysids as alternative live feeds in aquaculture. High nutritional value is present in amphipods and mysids, especially proteins, lipids, and essential fatty acids that are required by fish larvae during early development. Amphipods and mysids are considered abundant in the aquatic ecosystem and have been used by researchers in water toxicity studies. However, the culture of amphipods and mysids has been poorly studied. There is only a small-scale culture under laboratory conditions for scientific research that has been performed. Thus, further research is required to find a way to improve the mass culture of amphipods and mysids that can benefit the aquaculture industry. This review article is intended to provide the available information on amphipods and mysids, including reproductive biology, culture method, nutritional value, feed enhancement, and the importance of them as potential live feed in aquaculture. This article is useful as a guideline for researchers, hatchery operators, and farmers.
format: application/pdf
format: text/html
creator: Hidayu Suhaimi
creator: Muhammad Irfan Abdul Rahman
creator: Aisyah Ashaari
creator: Mhd Ikhwanuddin
creator: Nadiah Wan Rasdi
subject: Aquaculture, Fisheries and Fish Science
subject: Marine Biology
subject: Freshwater Biology
subject: Aquatic and Marine Chemistry
subject: Environmental Impacts
description: doi:10.7717/peerj.17092
publisher: PeerJ Inc.
rights: © 2024 Suhaimi et al.
abstract: Live foods such as phytoplankton and zooplankton are essential food sources in aquaculture. Due to their small size, they are suitable for newly hatched larvae. Artemia and rotifer are commonly used live feeds in aquaculture; each feed has a limited dietary value, which is unsuitable for all cultured species. Whereas, copepod and cladocerans species exhibit favorable characteristics that make them viable candidates as sources of essential nutrients for hatchery operations. Due to their jerking movements, it stimulates the feeding response of fish larvae, and their various sizes make them suitable for any fish and crustacean. Even though Artemia is the best live feed due to its proficient nutritional quality, the cost is very expensive, which is about half of the production cost. A recent study suggests the use of amphipods and mysids as alternative live feeds in aquaculture. High nutritional value is present in amphipods and mysids, especially proteins, lipids, and essential fatty acids that are required by fish larvae during early development. Amphipods and mysids are considered abundant in the aquatic ecosystem and have been used by researchers in water toxicity studies. However, the culture of amphipods and mysids has been poorly studied. There is only a small-scale culture under laboratory conditions for scientific research that has been performed. Thus, further research is required to find a way to improve the mass culture of amphipods and mysids that can benefit the aquaculture industry. This review article is intended to provide the available information on amphipods and mysids, including reproductive biology, culture method, nutritional value, feed enhancement, and the importance of them as potential live feed in aquaculture. This article is useful as a guideline for researchers, hatchery operators, and farmers.
bibliographic citation: Suhaimi et al. (2024) Adaptation and potential culture of wild Amphipods and Mysids as potential live feed in aquaculture: a review. PeerJ 12:e17092 https://doi.org/10.7717/peerj.17092
date submitted: 2023-07-31
date accepted: 2024-02-20
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Suhaimi
  given name: Hidayu
author list: Agent
  family name: Abdul Rahman
  given name: Muhammad Irfan
author list: Agent
  family name: Ashaari
  given name: Aisyah
author list: Agent
  family name: Ikhwanuddin
  given name: Mhd
author list: Agent
  family name: Wan Rasdi
  given name: Nadiah
doi: 10.7717/peerj.17092
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: © 2024 Suhaimi et al.
attribution name: Suhaimi et al.

The role of sirtuin1 in liver injury: molecular mechanisms and novel therapeutic target
type: item
type: AcademicArticle
description: Liver disease is a common and serious threat to human health. The progression of liver diseases is influenced by many physiologic processes, including oxidative stress, inflammation, bile acid metabolism, and autophagy. Various factors lead to the dysfunction of these processes and basing on the different pathogeny, pathology, clinical manifestation, and pathogenesis, liver diseases are grouped into different categories. Specifically, Sirtuin1 (SIRT1), a member of the sirtuin protein family, has been extensively studied in the context of liver injury in recent years and are confirmed the significant role in liver disease. SIRT1 has been found to play a critical role in regulating key processes in liver injury. Further, SIRT1 seems to cause divers outcomes in different types of liver diseases. Recent studies have showed some therapeutic strategies involving modulating SIRT1, which may bring a novel therapeutic target. To elucidate the mechanisms underlying the role of sirtuin1 in liver injury and its potentiality as a therapeutic target, this review outlines the key signaling pathways associated with sirtuin1 and liver injury, and discusses recent advances in therapeutic strategies targeting sirtuin1 in liver diseases.
format: application/pdf
format: text/html
creator: Mufei Wang
creator: Juanjuan Zhao
creator: Jiuxia Chen
creator: Teng Long
creator: Mengwei Xu
creator: Tingting Luo
creator: Qingya Che
creator: Yihuai He
creator: Delin Xu
subject: Biochemistry
subject: Molecular Biology
subject: Immunology
subject: Infectious Diseases
subject: Metabolic Sciences
description: doi:10.7717/peerj.17094
publisher: PeerJ Inc.
rights: © 2024 Wang et al.
abstract: Liver disease is a common and serious threat to human health. The progression of liver diseases is influenced by many physiologic processes, including oxidative stress, inflammation, bile acid metabolism, and autophagy. Various factors lead to the dysfunction of these processes and basing on the different pathogeny, pathology, clinical manifestation, and pathogenesis, liver diseases are grouped into different categories. Specifically, Sirtuin1 (SIRT1), a member of the sirtuin protein family, has been extensively studied in the context of liver injury in recent years and are confirmed the significant role in liver disease. SIRT1 has been found to play a critical role in regulating key processes in liver injury. Further, SIRT1 seems to cause divers outcomes in different types of liver diseases. Recent studies have showed some therapeutic strategies involving modulating SIRT1, which may bring a novel therapeutic target. To elucidate the mechanisms underlying the role of sirtuin1 in liver injury and its potentiality as a therapeutic target, this review outlines the key signaling pathways associated with sirtuin1 and liver injury, and discusses recent advances in therapeutic strategies targeting sirtuin1 in liver diseases.
bibliographic citation: Wang et al. (2024) The role of sirtuin1 in liver injury: molecular mechanisms and novel therapeutic target. PeerJ 12:e17094 https://doi.org/10.7717/peerj.17094
date submitted: 2023-07-21
date accepted: 2024-02-20
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Wang
  given name: Mufei
author list: Agent
  family name: Zhao
  given name: Juanjuan
author list: Agent
  family name: Chen
  given name: Jiuxia
author list: Agent
  family name: Long
  given name: Teng
author list: Agent
  family name: Xu
  given name: Mengwei
author list: Agent
  family name: Luo
  given name: Tingting
author list: Agent
  family name: Che
  given name: Qingya
author list: Agent
  family name: He
  given name: Yihuai
author list: Agent
  family name: Xu
  given name: Delin
doi: 10.7717/peerj.17094
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: ©2024 Wang et al.
attribution name: Wang et al.

Identifying app components that promote physical activity: a group concept mapping study
type: item
type: AcademicArticle
description: Background Digital interventions are a promising avenue to promote physical activity in healthy adults. Current practices recommend to include end-users early on in the development process. This study focuses on the wishes and needs of users regarding an a mobile health (mHealth) application that promotes physical activity in healthy adults, and on the differences between participants who do or do not meet the World Health Organization’s recommendation of an equivalent of 150 minutes of moderate intensity physical activity. Methods We used a mixed-method design called Group Concept Mapping. In a first phase, we collected statements completing the prompt “In an app that helps me move more, I would like to see/ do/ learn the following…” during four brainstorming sessions with physically inactive individuals (n = 19). The resulting 90 statements were then sorted and rated by a new group of participants (n = 46). Sorting data was aggregated, and (dis)similarity matrices were created using multidimensional scaling. Hierarchical clustering was applied using Ward’s method. Analyses were carried out for the entire group, a subgroup of active participants and a subgroup of inactive participants. Explorative analyses further investigated ratings of the clusters as a function of activity level, gender, age and education. Results Six clusters of statements were identified, namely ‘Ease-of-use and Self-monitoring’, ‘Technical Aspects and Advertisement’, ‘Personalised Information and Support’, ‘Motivational Aspects’, ‘Goal setting, goal review and rewards’, and ‘Social Features’. The cluster ‘Ease-of-use and Self-monitoring’ was rated highest in the overall group and the active subgroup, whereas the cluster ‘Technical Aspects and Advertisement’ was scored as most relevant in the inactive subgroup. For all groups, the cluster ‘Social Features’ was scored the lowest. Explorative analysis revealed minor between-group differences. Discussion The present study identified priorities of…
format: application/pdf
format: text/html
creator: Maya Braun
creator: Stéphanie Carlier
creator: Femke De Backere
creator: Marie Van De Velde
creator: Filip De Turck
creator: Geert Crombez
creator: Annick L. De Paepe
subject: Psychiatry and Psychology
subject: Public Health
subject: Human-Computer Interaction
description: doi:10.7717/peerj.17100
publisher: PeerJ Inc.
rights: © 2024 Braun et al.
abstract: Background Digital interventions are a promising avenue to promote physical activity in healthy adults. Current practices recommend to include end-users early on in the development process. This study focuses on the wishes and needs of users regarding an a mobile health (mHealth) application that promotes physical activity in healthy adults, and on the differences between participants who do or do not meet the World Health Organization’s recommendation of an equivalent of 150 minutes of moderate intensity physical activity. Methods We used a mixed-method design called Group Concept Mapping. In a first phase, we collected statements completing the prompt “In an app that helps me move more, I would like to see/ do/ learn the following…” during four brainstorming sessions with physically inactive individuals (n = 19). The resulting 90 statements were then sorted and rated by a new group of participants (n = 46). Sorting data was aggregated, and (dis)similarity matrices were created using multidimensional scaling. Hierarchical clustering was applied using Ward’s method. Analyses were carried out for the entire group, a subgroup of active participants and a subgroup of inactive participants. Explorative analyses further investigated ratings of the clusters as a function of activity level, gender, age and education. Results Six clusters of statements were identified, namely ‘Ease-of-use and Self-monitoring’, ‘Technical Aspects and Advertisement’, ‘Personalised Information and Support’, ‘Motivational Aspects’, ‘Goal setting, goal review and rewards’, and ‘Social Features’. The cluster ‘Ease-of-use and Self-monitoring’ was rated highest in the overall group and the active subgroup, whereas the cluster ‘Technical Aspects and Advertisement’ was scored as most relevant in the inactive subgroup. For all groups, the cluster ‘Social Features’ was scored the lowest. Explorative analysis revealed minor between-group differences. Discussion The present study identified priorities of…
bibliographic citation: Braun et al. (2024) Identifying app components that promote physical activity: a group concept mapping study. PeerJ 12:e17100 https://doi.org/10.7717/peerj.17100
date submitted: 2023-11-27
date accepted: 2024-02-21
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Braun
  given name: Maya
author list: Agent
  family name: Carlier
  given name: Stéphanie
author list: Agent
  family name: De Backere
  given name: Femke
author list: Agent
  family name: Van De Velde
  given name: Marie
author list: Agent
  family name: De Turck
  given name: Filip
author list: Agent
  family name: Crombez
  given name: Geert
author list: Agent
  family name: De Paepe
  given name: Annick L.
doi: 10.7717/peerj.17100
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: ©2024 Braun et al.
attribution name: Braun et al.

The effect of complex contrast training with different training frequency on the physical performance of youth soccer players: a randomized study
type: item
type: AcademicArticle
description: Background Complex contrast training (CCT) is potentially an efficient method to improve physical abilities such as muscle strength, power output, speed, agility, are extremely important in developing soccer players of different age categories. Aim This study aimed to analyze the effects of 6 weeks of CCT program applied in different training frequency (sessions per week) on youth soccer players performance. Methods Twenty-one youth soccer players (age: 15.3 ± 1.1 years; body mass 64.9 ± 0.7 kg; height 175.4 ± 0.7 cm) were randomized into three groups: a regular pre-season training control group (G0, n = 8), a group with regular pre-season training plus twice-a-week CCT (G2, n = 6), and a group with regular pre-season training plus thrice-a-week CCT (G3, n = 7). The CCT consisted of soccer skills-based exercises distributed across five stations, to be performed before common regular practice during a 6-week pre-season period. The agility (505 Agility test), sprint (S5 and S15), jump (SJ and CMJ), and free kick speed (11 m from the goal) of the groups were analyzed pre- and post-CCT intervention. During a 6-week pre-season period, the players integrated CCT into their regular training sessions. Furthermore, performance variables were compared between the groups. Results A statistical difference was identified for the timepoint for the players’ CMJ (p = 0.023; η2 = 0.343) and the free kick speed (p = 0.013; η2 = 0.383) using ANOVA. The G3 showed a significant improvement in the CMJ (p = 0.001) and the free kick speed (p = 0.003) between pre- to post-CCT test. No other significant changes in performance were observed (p > 0.05). Conclusion The CCT training program with a weekly frequency of 3 days per week is effective in improving free kick speed and CMJ performance in young male soccer players (U-15 and U-17 categories). CCT training programs have the potential to refine an athlete’s preparation for competition. However, certain performance tests did not demonstrate …
format: application/pdf
format: text/html
creator: Helder Barra-Moura
creator: João Guilherme Vieira
creator: Francisco Zacaron Werneck
creator: Michal Wilk
creator: Bruno Pascoalini
creator: Victor Queiros
creator: Gilmara Gomes de Assis
creator: Marta Bichowska-Pawęska
creator: Jeferson Vianna
creator: José Vilaça-Alves
subject: Kinesiology
subject: Sports Medicine
description: doi:10.7717/peerj.17103
publisher: PeerJ Inc.
rights: © 2024 Barra de Moura et al.
abstract: Background Complex contrast training (CCT) is potentially an efficient method to improve physical abilities such as muscle strength, power output, speed, agility, are extremely important in developing soccer players of different age categories. Aim This study aimed to analyze the effects of 6 weeks of CCT program applied in different training frequency (sessions per week) on youth soccer players performance. Methods Twenty-one youth soccer players (age: 15.3 ± 1.1 years; body mass 64.9 ± 0.7 kg; height 175.4 ± 0.7 cm) were randomized into three groups: a regular pre-season training control group (G0, n = 8), a group with regular pre-season training plus twice-a-week CCT (G2, n = 6), and a group with regular pre-season training plus thrice-a-week CCT (G3, n = 7). The CCT consisted of soccer skills-based exercises distributed across five stations, to be performed before common regular practice during a 6-week pre-season period. The agility (505 Agility test), sprint (S5 and S15), jump (SJ and CMJ), and free kick speed (11 m from the goal) of the groups were analyzed pre- and post-CCT intervention. During a 6-week pre-season period, the players integrated CCT into their regular training sessions. Furthermore, performance variables were compared between the groups. Results A statistical difference was identified for the timepoint for the players’ CMJ (p = 0.023; η2 = 0.343) and the free kick speed (p = 0.013; η2 = 0.383) using ANOVA. The G3 showed a significant improvement in the CMJ (p = 0.001) and the free kick speed (p = 0.003) between pre- to post-CCT test. No other significant changes in performance were observed (p > 0.05). Conclusion The CCT training program with a weekly frequency of 3 days per week is effective in improving free kick speed and CMJ performance in young male soccer players (U-15 and U-17 categories). CCT training programs have the potential to refine an athlete’s preparation for competition. However, certain performance tests did not demonstrate …
bibliographic citation: Barra-Moura et al. (2024) The effect of complex contrast training with different training frequency on the physical performance of youth soccer players: a randomized study. PeerJ 12:e17103 https://doi.org/10.7717/peerj.17103
date submitted: 2023-05-02
date accepted: 2024-02-21
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Barra-Moura
  given name: Helder
author list: Agent
  family name: Guilherme Vieira
  given name: João
author list: Agent
  family name: Zacaron Werneck
  given name: Francisco
author list: Agent
  family name: Wilk
  given name: Michal
author list: Agent
  family name: Pascoalini
  given name: Bruno
author list: Agent
  family name: Queiros
  given name: Victor
author list: Agent
  family name: Gomes de Assis
  given name: Gilmara
author list: Agent
  family name: Bichowska-Pawęska
  given name: Marta
author list: Agent
  family name: Vianna
  given name: Jeferson
author list: Agent
  family name: Vilaça-Alves
  given name: José
doi: 10.7717/peerj.17103
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: © 2024 Barra-Moura et al.
attribution name: Barra de Moura et al.

Expression profiles and gene set enrichment analysis of the transcriptomes from the cancer tissue, white adipose tissue and paracancer tissue with colorectal cancer
type: item
type: AcademicArticle
description: Background Colorectal cancer (CRC) is one of the most common cancers worldwide and is related to diet and obesity. Currently, crosstalk between lipid metabolism and CRC has been reported; however, the specific mechanism is not yet understood. In this study, we screened differentially expressed long non-coding RNAs (lncRNAs) and mRNAs from primary cancer, paracancer, and white adipose tissue of CRC patients. We screened and analyzed the genes differentially expressed between primary and paracancer tissue and between paracancer and white adipose tissue but not between primary and white adipose tissue. According to the results of the biological analysis, we speculated a lncRNA (MIR503HG) that may be involved in the crosstalk between CRC and lipid metabolism through exosome delivery. Methods We screened differentially expressed long non-coding RNAs (lncRNAs) and mRNAs from primary cancer, paracancer, and white adipose tissue of CRC patients. We screened and analyzed the genes differentially expressed between primary and paracancer tissue and between paracancer and white adipose tissue but not between primary and white adipose tissue. Results We speculated a lncRNA (MIR503HG) that may be involved in the crosstalk between CRC and lipid metabolism through exosome delivery. Conclusions In this study, the findings raise the possibility of crosstalk between lipid metabolism and CRC through the exosomal delivery of lncRNAs.
format: application/pdf
format: text/html
creator: Xiufeng Zhang
creator: Rui Zhu
creator: Ye Jiao
creator: Halizere Simayi
creator: Jialing He
creator: Zhong Shen
creator: Houdong Wang
creator: Jun He
creator: Suzhan Zhang
creator: Fei Yang
subject: Bioinformatics
subject: Gastroenterology and Hepatology
subject: Oncology
subject: Medical Genetics
description: doi:10.7717/peerj.17105
publisher: PeerJ Inc.
rights: © 2024 Zhang et al.
abstract: Background Colorectal cancer (CRC) is one of the most common cancers worldwide and is related to diet and obesity. Currently, crosstalk between lipid metabolism and CRC has been reported; however, the specific mechanism is not yet understood. In this study, we screened differentially expressed long non-coding RNAs (lncRNAs) and mRNAs from primary cancer, paracancer, and white adipose tissue of CRC patients. We screened and analyzed the genes differentially expressed between primary and paracancer tissue and between paracancer and white adipose tissue but not between primary and white adipose tissue. According to the results of the biological analysis, we speculated a lncRNA (MIR503HG) that may be involved in the crosstalk between CRC and lipid metabolism through exosome delivery. Methods We screened differentially expressed long non-coding RNAs (lncRNAs) and mRNAs from primary cancer, paracancer, and white adipose tissue of CRC patients. We screened and analyzed the genes differentially expressed between primary and paracancer tissue and between paracancer and white adipose tissue but not between primary and white adipose tissue. Results We speculated a lncRNA (MIR503HG) that may be involved in the crosstalk between CRC and lipid metabolism through exosome delivery. Conclusions In this study, the findings raise the possibility of crosstalk between lipid metabolism and CRC through the exosomal delivery of lncRNAs.
bibliographic citation: Zhang et al. (2024) Expression profiles and gene set enrichment analysis of the transcriptomes from the cancer tissue, white adipose tissue and paracancer tissue with colorectal cancer. PeerJ 12:e17105 https://doi.org/10.7717/peerj.17105
date submitted: 2023-12-19
date accepted: 2024-02-22
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Zhang
  given name: Xiufeng
author list: Agent
  family name: Zhu
  given name: Rui
author list: Agent
  family name: Jiao
  given name: Ye
author list: Agent
  family name: Simayi
  given name: Halizere
author list: Agent
  family name: He
  given name: Jialing
author list: Agent
  family name: Shen
  given name: Zhong
author list: Agent
  family name: Wang
  given name: Houdong
author list: Agent
  family name: He
  given name: Jun
author list: Agent
  family name: Zhang
  given name: Suzhan
author list: Agent
  family name: Yang
  given name: Fei
doi: 10.7717/peerj.17105
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: ©2024 Zhang et al.
attribution name: Zhang et al.

In the social amoeba Dictyostelium discoideum, shortened stalks may limit obligate cheater success even when exploitable partners are available
type: item
type: AcademicArticle
description: Cooperation is widespread across life, but its existence can be threatened by exploitation. The rise of obligate social cheaters that are incapable of contributing to a necessary cooperative function can lead to the loss of that function. In the social amoeba Dictyostelium discoideum, obligate social cheaters cannot form dead stalk cells and in chimeras instead form living spore cells. This gives them a competitive advantage within chimeras. However, obligate cheaters of this kind have thus far not been found in nature, probably because they are often enough in clonal populations that they need to retain the ability to produce stalks. In this study we discovered an additional cost to obligate cheaters. Even when there are wild-type cells to parasitize, the chimeric fruiting bodies that result have shorter stalks and these are disadvantaged in spore dispersal. The inability of obligate cheaters to form fruiting bodies when they are on their own combined with the lower functionality of fruiting bodies when they are not represent limits on obligate social cheating as a strategy.
format: application/pdf
format: text/html
creator: James Medina
creator: Tyler Larsen
creator: David C. Queller
creator: Joan E. Strassmann
subject: Cell Biology
subject: Evolutionary Studies
description: doi:10.7717/peerj.17118
publisher: PeerJ Inc.
rights: © 2024 Medina et al.
abstract: Cooperation is widespread across life, but its existence can be threatened by exploitation. The rise of obligate social cheaters that are incapable of contributing to a necessary cooperative function can lead to the loss of that function. In the social amoeba Dictyostelium discoideum, obligate social cheaters cannot form dead stalk cells and in chimeras instead form living spore cells. This gives them a competitive advantage within chimeras. However, obligate cheaters of this kind have thus far not been found in nature, probably because they are often enough in clonal populations that they need to retain the ability to produce stalks. In this study we discovered an additional cost to obligate cheaters. Even when there are wild-type cells to parasitize, the chimeric fruiting bodies that result have shorter stalks and these are disadvantaged in spore dispersal. The inability of obligate cheaters to form fruiting bodies when they are on their own combined with the lower functionality of fruiting bodies when they are not represent limits on obligate social cheating as a strategy.
bibliographic citation: Medina et al. (2024) In the social amoeba Dictyostelium discoideum, shortened stalks may limit obligate cheater success even when exploitable partners are available. PeerJ 12:e17118 https://doi.org/10.7717/peerj.17118
date submitted: 2023-10-16
date accepted: 2024-02-26
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Medina
  given name: James
author list: Agent
  family name: Larsen
  given name: Tyler
author list: Agent
  family name: Queller
  given name: David C.
author list: Agent
  family name: Strassmann
  given name: Joan E.
doi: 10.7717/peerj.17118
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: © 2024 Medina et al.
attribution name: Medina et al.

Bayesian estimation of the measurement of interactions in epidemiological studies
type: item
type: AcademicArticle
description: Background Interaction identification is important in epidemiological studies and can be detected by including a product term in the model. However, as Rothman noted, a product term in exponential models may be regarded as multiplicative rather than additive to better reflect biological interactions. Currently, the additive interaction is largely measured by the relative excess risk due to interaction (RERI), the attributable proportion due to interaction (AP), and the synergy index (S), and confidence intervals are developed via frequentist approaches. However, few studies have focused on the same issue from a Bayesian perspective. The present study aims to provide a Bayesian view of the estimation and credible intervals of the additive interaction measures. Methods Bayesian logistic regression was employed, and estimates and credible intervals were calculated from posterior samples of the RERI, AP and S. Since Bayesian inference depends only on posterior samples, it is very easy to apply this method to preventive factors. The validity of the proposed method was verified by comparing the Bayesian method with the delta and bootstrap approaches in simulation studies with example data. Results In all the simulation studies, the Bayesian estimates were very close to the corresponding true values. Due to the skewness of the interaction measures, compared with the confidence intervals of the delta method, the credible intervals of the Bayesian approach were more balanced and matched the nominal 95% level. Compared with the bootstrap method, the Bayesian method appeared to be a competitive alternative and fared better when small sample sizes were used. Conclusions The proposed Bayesian method is a competitive alternative to other methods. This approach can assist epidemiologists in detecting additive-scale interactions.
format: application/pdf
format: text/html
creator: Shaowei Lin
creator: Chanchan Hu
creator: Zhifeng Lin
creator: Zhijian Hu
subject: Mathematical Biology
subject: Epidemiology
subject: Data Mining and Machine Learning
description: doi:10.7717/peerj.17128
publisher: PeerJ Inc.
rights: © 2024 Lin et al.
abstract: Background Interaction identification is important in epidemiological studies and can be detected by including a product term in the model. However, as Rothman noted, a product term in exponential models may be regarded as multiplicative rather than additive to better reflect biological interactions. Currently, the additive interaction is largely measured by the relative excess risk due to interaction (RERI), the attributable proportion due to interaction (AP), and the synergy index (S), and confidence intervals are developed via frequentist approaches. However, few studies have focused on the same issue from a Bayesian perspective. The present study aims to provide a Bayesian view of the estimation and credible intervals of the additive interaction measures. Methods Bayesian logistic regression was employed, and estimates and credible intervals were calculated from posterior samples of the RERI, AP and S. Since Bayesian inference depends only on posterior samples, it is very easy to apply this method to preventive factors. The validity of the proposed method was verified by comparing the Bayesian method with the delta and bootstrap approaches in simulation studies with example data. Results In all the simulation studies, the Bayesian estimates were very close to the corresponding true values. Due to the skewness of the interaction measures, compared with the confidence intervals of the delta method, the credible intervals of the Bayesian approach were more balanced and matched the nominal 95% level. Compared with the bootstrap method, the Bayesian method appeared to be a competitive alternative and fared better when small sample sizes were used. Conclusions The proposed Bayesian method is a competitive alternative to other methods. This approach can assist epidemiologists in detecting additive-scale interactions.
bibliographic citation: Lin et al. (2024) Bayesian estimation of the measurement of interactions in epidemiological studies. PeerJ 12:e17128 https://doi.org/10.7717/peerj.17128
date submitted: 2023-09-11
date accepted: 2024-02-27
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Lin
  given name: Shaowei
author list: Agent
  family name: Hu
  given name: Chanchan
author list: Agent
  family name: Lin
  given name: Zhifeng
author list: Agent
  family name: Hu
  given name: Zhijian
doi: 10.7717/peerj.17128
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: ©2024 Lin et al.
attribution name: Lin et al.

Predicting the current fishable habitat distribution of Antarctic toothfish (Dissostichus mawsoni) and its shift in the future under climate change in the Southern Ocean
type: item
type: AcademicArticle
description: Global warming continues to exert unprecedented impacts on marine habitats. Species distribution models (SDMs) are proven powerful in predicting habitat distribution for marine demersal species under climate change impacts. The Antarctic toothfish, Dissostichus mawsoni (Norman 1937), an ecologically and commercially significant species, is endemic to the Southern Ocean. Utilizing occurrence records and environmental data, we developed an ensemble model that integrates various modelling techniques. This model characterizes species-environment relationships and predicts current and future fishable habitats of D. mawsoni under four climate change scenarios. Ice thickness, depth and mean water temperature were the top three important factors in affecting the distribution of D. mawsoni. The ensemble prediction suggests an overall expansion of fishable habitats, potentially due to the limited occurrence records from fishery-dependent surveys. Future projections indicate varying degrees of fishable habitat loss in large areas of the Amery Ice Shelf’s eastern and western portions. Suitable fishable habitats, including the spawning grounds in the seamounts around the northern Ross Sea and the coastal waters of the Bellingshausen Sea and Amundsen Sea, were persistent under present and future environmental conditions, highlighting the importance to protect these climate refugia from anthropogenic disturbance. Though data deficiency existed in this study, our predictions can provide valuable information for designing climate-adaptive development and conservation strategies in maintaining the sustainability of this species.
format: application/pdf
format: text/html
creator: Jie Liu
creator: Ancheng Zhu
creator: Xitao Wang
creator: Xiangjun Zhou
creator: Lu Chen
subject: Aquaculture, Fisheries and Fish Science
subject: Biogeography
subject: Ecology
subject: Zoology
subject: Climate Change Biology
description: doi:10.7717/peerj.17131
publisher: PeerJ Inc.
rights: © 2024 Liu et al.
abstract: Global warming continues to exert unprecedented impacts on marine habitats. Species distribution models (SDMs) are proven powerful in predicting habitat distribution for marine demersal species under climate change impacts. The Antarctic toothfish, Dissostichus mawsoni (Norman 1937), an ecologically and commercially significant species, is endemic to the Southern Ocean. Utilizing occurrence records and environmental data, we developed an ensemble model that integrates various modelling techniques. This model characterizes species-environment relationships and predicts current and future fishable habitats of D. mawsoni under four climate change scenarios. Ice thickness, depth and mean water temperature were the top three important factors in affecting the distribution of D. mawsoni. The ensemble prediction suggests an overall expansion of fishable habitats, potentially due to the limited occurrence records from fishery-dependent surveys. Future projections indicate varying degrees of fishable habitat loss in large areas of the Amery Ice Shelf’s eastern and western portions. Suitable fishable habitats, including the spawning grounds in the seamounts around the northern Ross Sea and the coastal waters of the Bellingshausen Sea and Amundsen Sea, were persistent under present and future environmental conditions, highlighting the importance to protect these climate refugia from anthropogenic disturbance. Though data deficiency existed in this study, our predictions can provide valuable information for designing climate-adaptive development and conservation strategies in maintaining the sustainability of this species.
bibliographic citation: Liu et al. (2024) Predicting the current fishable habitat distribution of Antarctic toothfish (Dissostichus mawsoni) and its shift in the future under climate change in the Southern Ocean. PeerJ 12:e17131 https://doi.org/10.7717/peerj.17131
date submitted: 2023-08-11
date accepted: 2024-02-27
issued: 2024-03-29
is part of: PeerJ
license: https://creativecommons.org/licenses/by/4.0/
author list: Agent
  family name: Liu
  given name: Jie
author list: Agent
  family name: Zhu
  given name: Ancheng
author list: Agent
  family name: Wang
  given name: Xitao
author list: Agent
  family name: Zhou
  given name: Xiangjun
author list: Agent
  family name: Chen
  given name: Lu
doi: 10.7717/peerj.17131
volume: 12
issn: 2167-8359
publication name: PeerJ
publication date: 2024-03-29
copyright: © 2024 Liu et al.
attribution name: Liu et al.

PeerJ
type: Periodical
uri: PeerJ
issn: 2167-8359