Peer-reviewed Articles

74 downloads
157 views

Background Clear cell renal cell carcinoma (ccRCC) is one of the most prevalent malignancies worldwide, N6-methyladenosine (m6A) has been shown to play important roles in regulating gene expression and phenotypes in both health and disease. Here, our purpose is...

["Bioinformatics","Oncology","Urology"]
doi:10.7717/peerj.8827
89 downloads
283 views

Tumour-associated macrophages (TAMs) are associated with both the progression and poor prognosis of a variety of solid tumours. This study aimed to investigate and clarify the tumour-promoting role of CXCL8 secreted by TAMs in the urothelial carcinoma microenvironment...

["Oncology","Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.8721
106 downloads
258 views

Purpose Erectile dysfunction (ED) is one of the most common male-disease globally. Despite efforts to explain its pathogenesis, the molecular mechanisms of ED are still not well understood. Methods The microarray dataset GSE10804 was downloaded from the Gene Expression...

["Bioinformatics","Anatomy and Physiology","Andrology","Urology"]
doi:10.7717/peerj.8653
29 downloads
149 views

Purpose Several nephrometry scoring systems have been developed based on two-dimensional computerized tomography images to quantify anatomical features of renal tumors. We have developed an accurate three-dimensional nephrometry scoring system to respond to the...

["Anatomy and Physiology","Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.8637
71 downloads
203 views

Circular RNAs (circRNAs) are a large class of endogenous RNA that form a covalently closed continuous loop without 5′ or 3′ tails and are diffusely expressed in mammalian cells. Through the development of high-throughput sequencing, microarray, and bioinformatics...

["Oncology","Urology"]
doi:10.7717/peerj.8666
84 downloads
202 views

Background To discuss the clinicopathological features and prognosis of patients with idiopathic membranous nephropathy (IMN) who are serum-negative for the anti-PLA2R antibody. Method Overall, 229 IMN patients were retrospectively collected in this study and classified...

["Evidence Based Medicine","Immunology","Nephrology","Urology"]
doi:10.7717/peerj.8650
59 downloads
171 views

Objective This study aimed to compare the efficacy and safety of Super-mini percutaneous nephrolithotomy (SMP) and flexible ureteroscopy (F-URS) in the treatment of 20–30 mm renal stones in obese patients. Methods We conducted a retrospective analysis of outcomes...

["Global Health","Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.8532
147 downloads
304 views

Background Our previous study demonstrated that the composition of the urinary microbiota in female patients with type 2 diabetes mellitus (T2DM) was correlated with the concentration of urinary interleukin (IL)-8. As the composition of urine is mainly determined...

["Microbiology","Diabetes and Endocrinology","Nutrition","Translational Medicine","Urology"]
doi:10.7717/peerj.8481
1 citation
64 downloads
239 views

Background Existing tools for chemometric analysis of vibrational spectroscopy data have enabled characterization of materials and biologicals by their broad molecular composition. The Rametrix™ LITE Toolbox v1.0 for MATLAB® is one such tool available publicly....

["Bioengineering","Computational Biology","Nephrology","Urology","Statistics"]
doi:10.7717/peerj.8179
122 downloads
291 views

Objective To analyze the clinical manifestations, diagnosis and treatment outcomes in a series of patients with epididymal tuberculosis. Methods This study is a retrospective data analysis of 47 cases of histologically-confirmed epididymal tuberculosis in patients...

["Andrology","Infectious Diseases","Urology"]
doi:10.7717/peerj.8291
174 downloads
719 views

Background Human intracellular chloride channel 3 (CLIC3) is involved in the development of various cancers, but the expression and prognostic value of CLIC3 mRNA in bladder cancer (BC) remain unclear. Methods The gene expression data and clinical information of...

["Bioinformatics","Oncology","Urology","Data Mining and Machine Learning"]
doi:10.7717/peerj.8348
271 downloads
545 views

There has been an increase in the mortality rate and morbidity of kidney cancer (KC) with kidney renal clear cell carcinoma (KIRC) being the most common subtype of KC. GRAMD1C (GRAM Domain Containing 1C) has not been reported to relate to prognosis and immunotherapy...

["Bioinformatics","Genomics","Oncology","Urology"]
doi:10.7717/peerj.8205
132 downloads
599 views

Background Pelvic floor pressure distribution profiles, obtained by a novel instrumented non-deformable probe, were used as the input to a feature extraction, selection, and classification approach to test their potential for an automatic diagnostic system for...

["Bioinformatics","Urology","Women\u2019s Health","Computational Science","Data Mining and Machine Learning"]
doi:10.7717/peerj.8207
139 downloads
920 views

Background Management of recurrent ureteral stricture is challenging. Consensus on the best surgical choice has not been demonstrated. In this study, we aim to report our experience in treating recurrent ureteral stricture and demonstrate whether robot-assisted...

["Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.8166
175 downloads
451 views

Purpose To investigate whether multi-view convolutional neural networks can improve a fully automated lymph node detection system for pelvic MR Lymphography (MRL) images of patients with prostate cancer. Methods A fully automated computer-aided detection (CAD)...

["Oncology","Radiology and Medical Imaging","Urology"]
doi:10.7717/peerj.8052

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