Peer-reviewed Articles

39 downloads
191 views

Background Optimization of transgene expression can be achieved by designing coding sequences with the synonymous codon usage of genes which are highly expressed in the host organism. The identification of the so-called “favoured codons” generally requires the...

["Bioinformatics","Biotechnology","Computational Biology","Genomics"]
doi:10.7717/peerj.5099
21 downloads
170 views

Matrix metallopeptidase 9 (MMP9) was found to be associated with tumor aggressiveness. In this study, we focused on the correlation between MMP9 expression and clear cell renal carcinoma (ccRCC). Through the Gene Expression Omnibus (GEO) database, the Cancer Genome...

["Cell Biology","Molecular Biology"]
doi:10.7717/peerj.5050
103 downloads
517 views

Terrestrial tardigrades, commonly known as “water bears”, are part of a phylum of microscopic, aquatic invertebrates famous for cryptobiosis and space travel, but little is known about their modes of dispersal on Earth. Wind is assumed, but not truly demonstrated,...

["Biogeography","Ecology","Population Biology"]
doi:10.7717/peerj.5035
39 downloads
233 views

Although polyploidy is considered a ubiquitous process in plants, the establishment of new polyploid species may be hindered by ecological competition with parental diploid taxa. In such cases, the adaptive processes that result in the ecological divergence of...

["Biogeography","Ecology","Plant Science"]
doi:10.7717/peerj.5209
35 downloads
285 views

Objective Cannabis, like other substances, negatively affects health, inducing respiratory problems and mental and cognitive alterations. Memory and learning disorders, as well as executive dysfunctions, are also neuropsychological disorders associated to cannabis...

["Neuroscience","Cognitive Disorders","Public Health"]
doi:10.7717/peerj.5201
425 downloads
2,209 views

Chasmosaurine ceratopsids are well documented from the Upper Cretaceous (Campanian) Dinosaur Park Formation (DPF) of southern Alberta and Saskatchewan, and include Chasmosaurus belli, Chasmosaurus russelli, Mercuriceratops gemini, Vagaceratops irvinensis, and material...

["Evolutionary Studies","Paleontology","Taxonomy"]
doi:10.7717/peerj.5194
27 downloads
200 views

Background Solute-linked carrier 26 gene family 6 (SLC26A6), which is mainly expressed in intestines and kidneys, is a multifunctional anion transporter crucial in the transport of oxalate anions. This study aimed to investigate the role of kidney SLC26A6 in urolithiasis....

["Biotechnology","Molecular Biology","Urology"]
doi:10.7717/peerj.5192
50 downloads
261 views

Background DNA sequences are pivotal for a wide array of research in biology. Large sequence databases, like GenBank, provide an amazing resource to utilize DNA sequences for large scale analyses. However, many sequence records on GenBank contain more than one...

["Bioinformatics","Evolutionary Studies","Genetics","Taxonomy"]
doi:10.7717/peerj.5179
40 downloads
680 views

Background Age and breed are considered the greatest risk factors for disease prevalence and mortality in companion dogs. Understanding the prevalence of diseases, in relation to age and breed, would support appropriate guidance for future health care strategies...

["Veterinary Medicine","Epidemiology","Evidence Based Medicine"]
doi:10.7717/peerj.5161
69 downloads
1,202 views

Amazonian bamboo forests dominated by large woody bamboo plants in the genus Guadua cover approximately 180,000 km2 and represent a key resource for many organisms. In southwestern Amazonia, native bamboo forests differ in structure, biodiversity, and growth dynamics...

["Biodiversity","Biogeography","Ecology","Entomology","Zoology"]
doi:10.7717/peerj.5153
56 downloads
1,137 views

Background Mosquito repellents can be an effective method for personal protection against mosquito bites that are a nuisance and carry the risk of transmission of mosquito-borne pathogens like plasmodia, dengue virus, chikungunya virus, and Zika virus. A multitude...

["Animal Behavior","Entomology","Public Health"]
doi:10.7717/peerj.5151
32 downloads
159 views

Time-resolved phylogenetic methods use information about the time of sample collection to estimate the rate of evolution. Originally, the models used to estimate evolutionary rates were quite simple, assuming that all lineages evolve at the same rate, an assumption...

["Bioinformatics","Genetics","Computational Science"]
doi:10.7717/peerj.5140
26 downloads
226 views

HLA class II proteins are important elements of human adaptive immune recognition and are associated with numerous infectious and immune-mediated diseases. These highly variable molecules can be classified into DP, DQ and DR groups. It has been proposed that in...

["Computational Biology","Immunology"]
doi:10.7717/peerj.5118
22 downloads
178 views

Aim X-chromosomal short tandem repeat (X-STR) loci are playing an increasingly important role in some complex kinship cases in recent years. To investigate the forensic efficiency of X-STRs of Mongolian minority group from Xinjiang Uygur Autonomous Region, China,...

["Evolutionary Studies","Genetics","Genomics"]
doi:10.7717/peerj.5117
33 downloads
208 views

Honey has been shown to have a range of therapeutic effects in humans, with anti-inflammatory and anti-bacterial effects among those previously characterised. Here, we examine the possibility of New Zealand thyme, manuka and honeydew honeys, and their major sugar...

["Cell Biology","Toxicology","Oncology","Pharmacology"]
doi:10.7717/peerj.5115

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