Peer-reviewed Articles

19 downloads
257 views

The major virulence factor of the pneumococcus, and target for conjugate vaccines, is the polysaccharide capsule, which is usually encoded by the highly variable cps locus. Serotype 37 is an unusual pneumococcal type in which the single β-glucosyltransferase gene...

["Bioinformatics","Genomics","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.3571
26 downloads
181 views

The skyline plot is a graphical representation of historical effective population sizes as a function of time. Past population sizes for these plots are estimated from genetic data, without a priori assumptions on the mathematical function defining the shape of...

["Computational Biology","Evolutionary Studies","Genetics","Statistics"]
doi:10.7717/peerj.3530
22 downloads
126 views

This study investigated whether zeolites of different size (Y30 (nano-sized) and H-Beta(OH)-III (forming large aggregates/agglomerates composed of 50 nm small primary particles)) exerted acute toxicity on larvae of the non-biting midge, Chironomus riparius, and...

["Environmental Sciences","Toxicology"]
doi:10.7717/peerj.3525
17 downloads
96 views

Background Recent climatic history has strongly impacted plant populations, but little is known about its effect on microbes. Alders, which host few and specific symbionts, have high genetic diversity in glacial refugia. Here, we tested the prediction that communities...

["Biodiversity","Biogeography","Ecology","Microbiology","Mycology"]
doi:10.7717/peerj.3479
21 downloads
147 views

The flower is a plant reproductive organ that forms part of the fruit produced as the flowering season ends. While the number and identity of proteins expressed in a jujube (Ziziphus jujuba Mill.) flower is currently unknown, integrative proteomic and transcriptomic...

["Agricultural Science","Genomics","Plant Science"]
doi:10.7717/peerj.3588
22 downloads
150 views

Gastric cancer (GC) is a complex disease with heterogeneous genetic mechanisms. Genomic mutational profiling of gastric cancer not only expands our knowledge about cancer progression at a fundamental genetic level, but also could provide guidance on new treatment...

["Computational Biology","Genomics","Oncology"]
doi:10.7717/peerj.3585
24 downloads
216 views

Wildlife conservation and management approaches typically focus on demographic measurements to assess population viability over both short and long periods. However, genetic diversity is an important predictor of long term population vitality. We investigated the...

["Conservation Biology","Genetics","Natural Resource Management"]
doi:10.7717/peerj.3584
32 downloads
166 views

Background The availability of large databases containing high resolution three-dimensional (3D) models of proteins in conjunction with functional annotation allows the exploitation of advanced supervised machine learning techniques for automatic protein function...

["Bioinformatics","Computational Biology","Data Mining and Machine Learning"]
doi:10.7717/peerj-cs.124
25 downloads
333 views

Aesop’s Fable tasks—in which subjects drop objects into a water-filled tube to raise the water level and obtain out-of-reach floating rewards —have been used to test for causal understanding of water displacement in both young children and non-human animals. However,...

["Animal Behavior","Psychiatry and Psychology"]
doi:10.7717/peerj.3484
13 downloads
130 views

Objective Osteoarthritis (OA) is a disease characterized by degeneration of joint cartilage. It is associated with pain and disability and is the result of either age and activity related joint wear or an injury. Non-invasive treatment options are scarce and prevention...

["Mathematical Biology","Orthopedics"]
doi:10.7717/peerj.3468
64 downloads
383 views

Objective The aim of our study was to identify barriers and enablers to implementation of the Xpert MTB/RIF test within Mongolia’s National Tuberculosis Program. Methods Twenty-foursemi-structured interviews were conducted between June and September 2015 with laboratory...

["Infectious Diseases","Public Health"]
doi:10.7717/peerj.3567
14 downloads
167 views

Cognitive functioning is vital for enabling animals of all taxa to optimise their chances of survival and reproductive success. Learning and memory in particular are drivers of many evolutionary processes. In this study, we examine how developmental plasticity...

["Animal Behavior","Zoology"]
doi:10.7717/peerj.3563
325 downloads
173 views

Hydrocarbons are the principal component of insect cuticle and play an important role in maintaining water balance. Cuticular impermeability could be an adaptative response to salinity and desiccation in aquatic insects; however, cuticular hydrocarbons have been...

["Ecology","Entomology"]
doi:10.7717/peerj.3562
26 downloads
283 views

Terrestrial eggs have evolved repeatedly in tropical anurans exposing embryos to the new threat of dehydration. Red-eyed treefrogs, Agalychnis callidryas, lay eggs on plants over water. Maternally provided water allows shaded eggs in humid sites to develop to hatching...

["Developmental Biology","Ecology","Zoology"]
doi:10.7717/peerj.3549
38 downloads
461 views

We characterize the diversity of nectar-living yeasts of a tropical host plant community at different hierarchical sampling levels, measure the associations between yeasts and nectariferous plants, and measure the effect of yeasts on nectar traits. Using a series...

["Ecology","Microbiology","Mycology","Plant Science"]
doi:10.7717/peerj.3517

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