Peer-reviewed Articles

19 downloads
288 views

Objective Bladder cancer is a cause of considerable morbidity worldwide. Electromotive Drug Administration is a method that combines intravesical chemotherapy with local electric field application. Electroporation has been suggested among other mechanisms as having...

["Biophysics","Drugs and Devices","Oncology","Radiology and Medical Imaging","Urology"]
doi:10.7717/peerj.2309
42 downloads
277 views

In the midst of the current biodiversity crisis, conservation efforts might profitably be directed towards ensuring that extinctions do not result in inordinate losses of evolutionary history. Numerous methods have been developed to evaluate the importance of species...

["Biodiversity","Conservation Biology","Evolutionary Studies"]
doi:10.7717/peerj.2350
41 downloads
379 views

Background Vestimentiferan tubeworms are some of the most recognizable fauna found at deep-sea cold seeps, isolated environments where hydrocarbon rich fluids fuel biological communities. Several studies have investigated tubeworm population structure; however,...

["Conservation Biology","Ecology","Genetics","Genomics","Marine Biology"]
doi:10.7717/peerj.2366
46 downloads
509 views

We present the phylogeny analysis software SICLE (Sister Clade Extractor), an easy-to-use, high-throughput tool to describe the nearest neighbors to a node of interest in a phylogenetic tree as well as the support value for the relationship. The application is...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.2359
38 downloads
328 views

Background Measurement of lumbar spine range of motion (ROM) is often considered to be an essential component of lumbar spine physiotherapy and orthopedic assessment. The measurement can be carried out through various instruments such as inclinometers, goniometers,...

["Anatomy and Physiology","Kinesiology","Orthopedics"]
doi:10.7717/peerj.2355
38 downloads
239 views

Small mammals play important roles in many ecosystems, and understanding their response to disturbances such as cattle grazing is fundamental for developing sustainable land use strategies. However, how small mammals respond to cattle grazing remains controversial....

["Biodiversity","Conservation Biology","Ecology"]
doi:10.7717/peerj.2349
28 downloads
673 views

Background: Information on cardiovascular gene transcription is fragmented and far behind the present requirements of the systems biology field. To create a comprehensive source of data for cardiovascular gene regulation and to facilitate a deeper understanding...

["Bioinformatics","Computational Biology","Cardiology","Computational Science"]
doi:10.7717/peerj.2339
52 downloads
473 views

The taxonomic knowledge about immature stages of the insect order Odonata (dragonflies and damselflies) is rather limited in tropical America. Here, the larvae of Epigomphus jannyae Belle, 1993 and E. tumefactus Calvert, 1903 are described, figured, and compared...

["Entomology","Taxonomy"]
doi:10.7717/peerj.2338
27 downloads
276 views

Throughout much of North America’s boreal forest, the cyclical fluctuations of snowshoe hare populations (Lepus americanus) may cause other herbivores to become entrained in similar cycles. Alternating apparent competition via prey switching followed by positive...

["Conservation Biology","Ecology","Zoology"]
doi:10.7717/peerj.2303
146 downloads
986 views

Footprint morphology (e.g., outline shape, depth of impression) is one of the key diagnostic features used in the interpretation of ancient vertebrate tracks. Over 80 tridactyl tracks, confined to the same bedding surface in the Lower Jurassic Elliot Formation...

["Environmental Sciences","Paleontology"]
doi:10.7717/peerj.2285
33 downloads
222 views

This study examined developmental toxicity of different mercury compounds, including some used in traditional medicines. Medaka (Oryzias latipes) embryos were exposed to 0.001–10 µM concentrations of MeHg, HgCl2, α-HgS (Zhu Sha), and β-HgS (Zuotai) from stage 10...

["Aquaculture, Fisheries and Fish Science","Developmental Biology","Toxicology","Pharmacology","Public Health"]
doi:10.7717/peerj.2282
38 downloads
181 views

Background The receptor activator of nuclear factor kappa-B (RANK)/RANK ligand/osteoprotegerin (OPG) system plays a critical role in bone remodelling by regulating osteoclast formation and activity. OPG has been used systemically in the treatment of bone diseases....

["Bioengineering","Orthopedics","Pharmacology"]
doi:10.7717/peerj.2229
35 downloads
202 views

We propose a multi-scale image fusion scheme based on guided filtering. Guided filtering can effectively reduce noise while preserving detail boundaries. When applied in an iterative mode, guided filtering selectively eliminates small scale details while restoring...

["Computer Vision"]
doi:10.7717/peerj-cs.80
28 downloads
112 views

Timing Speculation (TS) is a widely known method for realizing better-than-worst-case systems. Aggressive clocking, realizable by TS, enable systems to operate beyond specified safe frequency limits to effectively exploit the data dependent circuit delay. However,...

["Algorithms and Analysis of Algorithms","Computer Architecture","Embedded Computing","Emerging Technologies"]
doi:10.7717/peerj-cs.79
37 downloads
455 views

Publication and archival of scientific results is still commonly considered the responsability of classical publishing companies. Classical forms of publishing, however, which center around printed narrative articles, no longer seem well-suited in the digital age....

["Bioinformatics","Computer Networks and Communications","Digital Libraries","World Wide Web and Web Science"]
doi:10.7717/peerj-cs.78

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