Peer-reviewed Articles

25 downloads
124 views

Background Growth arrest and DNA-damage-inducible protein 45 alpha (GADD45A) was previously found to be associated with risk of several kinds of human tumors. Here, we studied the expression and clinical significance of GADD45A in breast cancer. Methods We performed...

["Oncology","Translational Medicine"]
doi:10.7717/peerj.5344
34 downloads
151 views

Satellite chlorophyll a (chl a) observations have repeatedly noted summertime phytoplankton blooms in the North Pacific subtropical gyre (NPSG), a region of open ocean that is far removed from any land-derived or Ekman upwelling nutrient sources. These blooms are...

["Ecosystem Science","Marine Biology","Biological Oceanography"]
doi:10.7717/peerj.5387
30 downloads
397 views

Background When suffering from chronic pain, attempts to control or avoid pain often compete with other daily activities. Engaging in one activity excludes engaging in another, equally valued activity, which is referred to as “goal conflict.” As yet, the presence...

["Anesthesiology and Pain Management","Psychiatry and Psychology","Public Health","Translational Medicine"]
doi:10.7717/peerj.5272
72 downloads
572 views

The CHARMM36 force field for lipids is widely used in simulations of lipid bilayers. The CHARMM family of force fields were developed for use with the mTIP3P water model. This water model has an anomalously high dielectric constant and low viscosity, which limits...

["Biochemistry","Biophysics","Computational Biology"]
doi:10.7717/peerj.5472
41 downloads
164 views

Sponges are ubiquitous on coral reefs, mostly long lived and therefore adaptive to changing environmental conditions. They feed on organic matter withdrawn from the passing water and they may harbor microorganisms (endosymbionts), which contribute to their nutrition....

["Ecology","Marine Biology","Biological Oceanography"]
doi:10.7717/peerj.5460
42 downloads
258 views

The invasive Asian shore crab, Hemigrapsus sanguineus, is ubiquitous in the rocky intertidal zone of the western North Atlantic. A likely contributor to this colonization is that H. sanguineus is able to handle a wide range of salinities, and is thus more likely...

["Marine Biology","Biological Oceanography"]
doi:10.7717/peerj.5446
64 downloads
312 views

Background Spatial scale is important when studying ecological processes. The Greater sage-grouse (Centrocercus urophasianus) is a large sexually dimorphic tetraonid that is endemic to the sagebrush biome of western North America. The impacts of oil and gas (OAG)...

["Conservation Biology","Ecology","Natural Resource Management","Environmental Impacts"]
doi:10.7717/peerj.5417
34 downloads
110 views

Background Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used in clinical practice, which can have adverse effects on the osteoblast. The objective of this study was to determine the effect of NSAIDs on the osteoblast by analyzing the gene expression...

["Drugs and Devices","Pharmacology"]
doi:10.7717/peerj.5415
48 downloads
349 views

Roads may have an important negative effect on animal dispersal rate and mortality and thus the functioning of local populations. However, road verges may be surrogate habitats for invertebrates. This creates a conservation dilemma around the impact of roads on...

["Biodiversity","Conservation Biology","Ecology","Entomology","Zoology"]
doi:10.7717/peerj.5413
33 downloads
152 views

Antarctica, with its severe conditions, is poor in terrestrial fauna species. However, an increase in human presence together with climate change may cause an influx of non-native species. Here we report a significant increase in colonized area of one of the few...

["Biodiversity","Conservation Biology","Ecology","Ecosystem Science"]
doi:10.7717/peerj.5408
25 downloads
167 views

Background Acute kidney injury (AKI) is associated with a significant increase in morbidity, mortality, and health care costs. In intensive care units (ICU), AKI is commonly multifactorial and frequently involves diverse factors, such as hypovolemia, sepsis, and...

["Nephrology","Pharmacology","Public Health"]
doi:10.7717/peerj.5405
95 downloads
869 views

Background Tar seep deposits in South America historically are well-known for their rich record of fossil mammals, contrasting with only a few formal reports of reptile remains. Here we report a new snake fauna recovered from two tar pits from Venezuela. The fossil...

["Biogeography","Evolutionary Studies","Paleontology","Taxonomy","Zoology"]
doi:10.7717/peerj.5402
49 downloads
177 views

A residue from the primary treatment of a Wastewater Treatment Plant (WWTP) was used to isolate filamentous fungi with lipase production potential. Two of the 27 isolated fungi presented high hydrolysis index and were selected for lipase production by solid-state...

["Biotechnology","Environmental Contamination and Remediation","Green Chemistry"]
doi:10.7717/peerj.5368
54 downloads
258 views

We investigated a pantropical sub-family and genus of damselfishes, the sergeant-majors (Pomacentridae: Abudefdufinae: Abudefduf), to identify the tempo and mechanisms of speciation in the lineage. We examined sequence capture data from 500 loci and 20 species,...

["Biodiversity","Biogeography","Zoology"]
doi:10.7717/peerj.5357
47 downloads
237 views

Background Bacteria, archaea, viruses and fungi live in various plant compartments including leaves and roots. These plant-associated microbial communities have many effects on host fitness and function. Global climate change is impacting plant species distributions,...

["Ecology","Genomics","Microbiology","Plant Science","Climate Change Biology"]
doi:10.7717/peerj.5293

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