Peer-reviewed Articles - Medicine

94 downloads
819 views

Background MicroRNA (miRNA) regulates cellular processes by acting on specific target genes, and cellular processes proceed through multiple interactions often organized into pathways among genes and gene products. Hundreds of miRNAs and their target genes have...

["Bioinformatics","Translational Medicine","Medical Genetics","Computational Science","Data Mining and Machine Learning"]
doi:10.7717/peerj.7309
66 downloads
257 views

Background Road traffic accidents are one of the serious disasters that cause public injury, fatality and great economic loss. They are a growing public health problem around the world. Objectives The aim of this study was to determine epidemiological characteristics,...

["Epidemiology","Public Health","Statistics"]
doi:10.7717/peerj.7423
53 downloads
318 views

Background Osteoarthritis (OA) is characterized by the degeneration of joint cartilage, with concomitant changes in the synovium and subchondral bone. Recently, the inflammatory response and involvement of several types of T-cells has been implicated in the development...

["Immunology","Orthopedics","Rheumatology"]
doi:10.7717/peerj.7443
67 downloads
212 views

Background. Men and women differ in their susceptibility to cardiovascular disease, though the underlying mechanism has remained elusive. Heart disease symptoms, evolution and response to treatment are often sex-specific. This has been studied in animal models...

["Anatomy and Physiology","Cardiology"]
doi:10.7717/peerj.7461
66 downloads
226 views

This study aimed to research the effects of different dietary concentrate to forage (C:F) ratio on growth performance, rumen fermentation and bacteria diversity of barn feeding Tibetan sheep. The experiment contains fiver treatments (HS1, HS2 HS3, HS4 and HS5;...

["Biodiversity","Microbiology","Veterinary Medicine","Zoology","Nutrition"]
doi:10.7717/peerj.7462
73 downloads
247 views

Epididymal protease inhibitor (EPPIN) that is located on the sperm surface and specific to the male reproductive system is a non-hormonal contraceptive target, since the binding of EPPIN with the seminal plasma protein semenogelin-1 (SEMG1) causes a loss of sperm...

["Bioinformatics","Computational Biology","Andrology","Computational Science"]
doi:10.7717/peerj.7329
84 downloads
314 views

The purpose of this study is to investigate the effects of different types of acute exercise on cognitive function and cerebral oxygenation. A within-subject design was adopted. In total, 20 healthy older adults were enrolled in the study. They came to the laboratory...

["Neuroscience","Geriatrics","Neurology","Ophthalmology"]
doi:10.7717/peerj.7418
53 downloads
209 views

Desiccation is one of the extremely stressful situations experienced by aquatic animals, and sea cucumber usually suffers from desiccation stress during transportation without water. The present study was conducted to evaluate the effect of desiccation and subsequent...

["Aquaculture, Fisheries and Fish Science","Marine Biology","Immunology","Metabolic Sciences","Environmental Impacts"]
doi:10.7717/peerj.7427
65 downloads
236 views

Cytochrome P450s (CYPs) are phase-I metabolic enzymes playing important roles in drug metabolism, dietary chemicals and endogenous molecules. Age is a key factor influencing P450s expression. Thus, age-related changes of CYP 1–4 families and bile acid homeostasis-related...

["Biochemistry","Toxicology","Pharmacology","Metabolic Sciences"]
doi:10.7717/peerj.7429
74 downloads
204 views

An ideal suture material supports healing, minimizes inflammation, and decreases the likelihood of secondary infection. While there are published recommendations for suture materials in some invertebrates, there are no published recommendations for Limulus polyphemus...

["Marine Biology","Veterinary Medicine","Surgery and Surgical Specialties"]
doi:10.7717/peerj.7061
86 downloads
434 views

Background Rattus rattus is a widely distributed, invasive species that presents an important role in disease transmission, either directly or through vector arthropods such as fleas. These black rats can transmit a wide variety of pathogens, including bacteria...

["Parasitology","Veterinary Medicine","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.7371
73 downloads
314 views

Background Oxidative stress modulates insulin resistant-related atherogenic dyslipidemia: hypertriglyceridemia (HTG) and low high-density lipoprotein cholesterol (HDL-C) level. Gene polymorphisms in superoxide dismutase (SOD2 and SOD3), glutathione peroxidase-3...

["Bioinformatics","Cardiology","Diabetes and Endocrinology","Medical Genetics","Metabolic Sciences"]
doi:10.7717/peerj.7407
100 downloads
494 views

Background Many studies have shown that long noncoding RNAs (lncRNA) are closely associated with the occurrence and development of various tumors and have the potential to be prognostic markers. Moreover, cirrhosis is an important prognostic risk factors in patients...

["Bioinformatics","Genomics","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.7413
70 downloads
297 views

Background During steady walking, gait parameters fluctuate from one stride to another with complex fractal patterns and long-range statistical persistence. When a metronome is used to pace the gait (sensorimotor synchronization), long-range persistence is replaced...

["Bioengineering","Kinesiology","Computational Science"]
doi:10.7717/peerj.7417
107 downloads
289 views

Background Rho GTPase-activating protein 10 (ARHGAP10), which catalyzes the conversion of active Rho GTPase to the inactive form, is downregulated in some cancers. However, little is known about ARHGAP10 in breast cancer. Methods The transcriptional expression...

["Bioinformatics","Oncology"]
doi:10.7717/peerj.7431

Refine by manuscript type

Top subject areas - Articles

Top subject areas - People

View all subject areas