Peer-reviewed Articles - Medicine

36 downloads
410 views

Polyaniline (PANI) and functionalised polyanilines (fPANI) are novel antimicrobial agents whose mechanism of action was investigated. Escherichia coli single gene deletion mutants revealed that the antimicrobial mechanism of PANI likely involves production of hydrogen...

["Microbiology","Molecular Biology","Infectious Diseases"]
doi:10.7717/peerj.5135
195 downloads
6,563 views

Purpose The relationship between changes in muscle size and strength may be affected by both measurement and statistical approaches, but their effects have not been fully considered or quantified. Therefore, the purpose of this investigation was to explore how...

["Kinesiology","Statistics"]
doi:10.7717/peerj.5071
80 downloads
572 views

This paper proposes a new methodology to quantify patterns of egg shape variation using geometric morphometrics of three-dimensional landmarks captured on digitally reconstructed eggshells and demonstrates its performance in capturing shape variation at multiple...

["Ecology","Evolutionary Studies","Zoology","Anatomy and Physiology"]
doi:10.7717/peerj.5052
42 downloads
228 views

Purpose RNA sequencing analysis has demonstrated bidirectional changes in metabolism, structural and immune pathways during early induction of defocus induced myopia. Thus, the aim of this study was to investigate whether similar gene pathways are also related...

["Bioinformatics","Genomics","Molecular Biology","Neuroscience","Ophthalmology"]
doi:10.7717/peerj.5048
43 downloads
231 views

Background Craniofacial dysmorphic features are morphological changes of the face and skull which are associated with syndromic conditions. Moyamoya angiopathy is a rare cerebral vasculopathy that can be divided into Moyamoya syndrome, which is associated or secondary...

["Genetics","Neurology"]
doi:10.7717/peerj.4740
37 downloads
304 views

Objective This study was undertaken to detect if free fatty acids (FFA) induce hepatocyte senescence in L-02 cells and if huperzine A has an anti-aging effect in fatty liver cells. Methods L-02 cells were treated with a FFA mixture (oleate/palmitate, at 3:0, 2:1,...

["Gastroenterology and Hepatology","Pharmacology","Medical Genetics","Metabolic Sciences"]
doi:10.7717/peerj.5145
46 downloads
209 views

Depressive disorders (DD) are known to be associated with increased DNA damage, the impairment of DNA damage repair, and the presence of single-nucleotide polymorphisms (SNPs) in DNA damage repair genes. Some indirect evidence also suggests that uracil metabolism...

["Genetics","Cognitive Disorders","Pharmacology","Psychiatry and Psychology"]
doi:10.7717/peerj.5116
30 downloads
205 views

Background Genome-wide association studies have identified a plethora of risk genes for both Crohn’s disease (CD) and ankylosing spondylitis (AS). A subset of genes found to be risk factors for CD have also been found to be risk factors for AS. The objective of...

["Genetics","Rheumatology"]
doi:10.7717/peerj.5088
109 downloads
534 views

The present study comprises the synthesis of a new series of sulfonamides derived from 4-methoxyphenethylamine (1). The synthesis was initiated by the reaction of 1 with 4-methylbenzenesulfonyl chloride (2) in aqueous sodium carbonate solution at pH 9 to yield...

["Bioinformatics","Neuroscience","Cognitive Disorders","Drugs and Devices"]
doi:10.7717/peerj.4962
53 downloads
284 views

Background Influenza epidemics pose significant social and economic challenges in China. Internet search query data have been identified as a valuable source for the detection of emerging influenza epidemics. However, the selection of the search queries and the...

["Health Policy","Infectious Diseases"]
doi:10.7717/peerj.5134
51 downloads
251 views

Swimmer’s itch is a re-emerging human disease caused by bird schistosome cercariae, which can infect bathing or working people in water bodies. Even if cercariae fail after penetrating the human skin, they can cause dangerous symptoms in atypical mammal hosts....

["Ecology","Parasitology","Zoology","Public Health","Freshwater Biology"]
doi:10.7717/peerj.5045
40 downloads
227 views

Several studies have indicated that α-mangostin exerts anti-metastasis and anti-subsistence effects on several types of cancer cells. Especially, the anti-metastatic effect of α-mangostin on cancer cells is a prospective function in cancer treatment. However, the...

["Biotechnology","Cell Biology","Oncology"]
doi:10.7717/peerj.5027
51 downloads
195 views

Background Supplemental feeding of free-roaming animals, including wildlife and feral or stray animals, is well known to have a substantial impact on various aspects of animal ecology including habitat use, activity patterns, and host-pathogen interactions. Among...

["Ecology","Veterinary Medicine","Infectious Diseases","Public Health","Population Biology"]
doi:10.7717/peerj.4988
44 downloads
276 views

A serious concern is arising on the coexistence of extended-spectrum beta-lactamase (ESBL) and plasmid mediated quinolone resistance (PMQR) producing bacteria in animal husbandry, which could be transferred to humans, especially in strains that may not be routinely...

["Genetics","Microbiology","Infectious Diseases"]
doi:10.7717/peerj.5053
246 downloads
17,683 views

Background The objective of the present study was to compare the effects of equal-volume resistance training (RT) performed with different training frequencies on muscle size and strength in trained young men. Methods Sixteen men with at least one year of RT experience...

["Kinesiology"]
doi:10.7717/peerj.5020

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