Peer-reviewed Articles - Medicine

72 downloads
243 views

Purpose Most studies on neuroblastoma (NB) have been conducted in Western countries or Japan. The objective of our study was to analyze clinical and pathological features, MYCN status, surgical methods, and prognosis in Chinese NB patients. Methods A retrospective,...

["Oncology","Pediatrics","Surgery and Surgical Specialties"]
doi:10.7717/peerj.5665
68 downloads
447 views

Background Schizotypy is a set of personality traits that resemble the signs and symptoms of schizophrenia in the general population, and it is associated with various subclinical mental health problems, including sleep disturbances. Additionally, dimensions of...

["Cognitive Disorders","Global Health","Psychiatry and Psychology"]
doi:10.7717/peerj.5615
57 downloads
616 views

Objectives The five-year survival rate of head and neck cancer (HNC) after radiotherapy (RT) varies widely from 35% to 89%. Many studies have addressed the effect of socioeconomic status and urban dwelling on the survival of HNC, but a limited number of studies...

["Dentistry","Oncology","Otorhinolaryngology","Public Health"]
doi:10.7717/peerj.5591
53 downloads
218 views

Combination Index (CI) analysis suggested that MBIC and doxorubicin synergistically inhibited up to 97% of cell proliferation in ER+/PR+MCF-7 and triple negative MDA-MB-231 breast cancer cell lines. Moreover, treatment of the breast cancer cells with the combined...

["Cell Biology","Oncology"]
doi:10.7717/peerj.5577
59 downloads
307 views

Background High myopia is a common ocular disease worldwide. To expand our current understanding of the genetic basis of high myopia, we carried out a whole exome sequencing (WES) study to identify potential causal gene mutations. Methods A total of 20 individuals...

["Bioinformatics","Computational Biology","Genetics","Genomics","Translational Medicine"]
doi:10.7717/peerj.5552
75 downloads
708 views

Background Silver nanoparticles (AgNPs) have been widely used in many commercial products due to their excellent antibacterial ability. The AgNPs are released into the environment, gradually accumulate in the ocean, and may affect animals at high trophic levels,...

["Toxicology","Veterinary Medicine","Immunology","Ecotoxicology","Environmental Contamination and Remediation"]
doi:10.7717/peerj.5432
64 downloads
278 views

Background The leading cause of surface water impairment in United States’ rivers and streams is pathogen contamination. Although use of fecal indicators has reduced human health risk, current approaches to identify and reduce exposure can be improved. One important...

["Microbiology","Public Health","Computational Science","Data Mining and Machine Learning","Spatial and Geographic Information Science"]
doi:10.7717/peerj.5610
55 downloads
215 views

Background Urothelial carcinoma (UC) is the fifth most common malignancy that accounts for 5% of all cancers. Diagnostic markers that predict UC progressions are inadequate. NF-κB contributes towards disease progression upon constitutive activation in many solid...

["Bioinformatics","Pathology","Urology"]
doi:10.7717/peerj.5563
51 downloads
312 views

Background The Mini-IPIP scales (Donellan et al., 2006) are possibly one of the most commonly used short inventories for measuring the Big Five Factors of personality. In this study, we aimed to investigate the psychometric properties of two Mini-IPIP Spanish short...

["Psychiatry and Psychology","Statistics"]
doi:10.7717/peerj.5542
59 downloads
516 views

Background Autonomic dysfunction (AD) is one of the non-motor features of Parkinson’s disease (PD). Some symptoms tend to occur in the early stages of PD. AD also has a great impact on patient’s quality of life. In this study, we aimed to discover the association...

["Neurology","Radiology and Medical Imaging"]
doi:10.7717/peerj.5539
47 downloads
202 views

Background Abnormal methylation of TNFRSF10C was found to be associated with different types of cancers, excluding colorectal cancer (CRC). In this paper, the performance of TNFRSF10C methylation in CRC was studied in two stages. Method The discovery stage was...

["Biochemistry","Genetics","Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5336
77 downloads
515 views

Background Undisputedly, traffic crashes constitute a public health concern whose impact and importance have been increasing during the past few decades. Specifically, road safety data have systematically shown how cyclists are highly vulnerable to suffering traffic...

["Global Health","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.5616
89 downloads
664 views

Most researchers do not deliberately claim causal results in an observational study. But do we lead our readers to draw a causal conclusion unintentionally by explaining why significant correlations and relationships may exist? Here we perform a randomized controlled...

["Psychiatry and Psychology","Science and Medical Education","Statistics"]
doi:10.7717/peerj.5597
36 downloads
209 views

One purpose of wikis is the collaborative generation of content. During creation processes, controversies between authors emerge that they discuss on the article’s talk page. Research suggests that controversies based on opposing points of view and contradictory...

["Psychiatry and Psychology","Human-Computer Interaction","Computational Science"]
doi:10.7717/peerj.5541
45 downloads
297 views

Chemerin is an adipocyte derived signalling molecule (adipokine) that serves as a ligand activator of Chemokine-like receptor 1(CMKLR1). Chemerin/CMKLR1 signalling is well established to regulate fundamental processes in metabolism and inflammation. The composition...

["Bioinformatics","Genomics","Diabetes and Endocrinology","Metabolic Sciences"]
doi:10.7717/peerj.5494

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