Peer-reviewed Articles - Medicine

65 downloads
392 views

Background Liver hepatocellular carcinoma accounts for the overwhelming majority of primary liver cancers and its belated diagnosis and poor prognosis call for novel biomarkers to be discovered, which, in the era of big data, innovative bioinformatics and computational...

["Bioinformatics","Computational Biology","Oncology","Pathology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3089
22 downloads
203 views

Background Electronic Health Record (EHR)-based sepsis alert systems have failed to demonstrate improvements in clinically meaningful endpoints. However, the effect of implementation barriers on the success of new sepsis alert systems is rarely explored. Objective...

["Bioinformatics","Emergency and Critical Care","Human-Computer Interaction"]
doi:10.7717/peerj.3083
35 downloads
142 views

Background Dengue is a global human public health threat, causing severe morbidity and mortality. The occurrence of sequential infection by more than one serotype of dengue virus (DENV) is a major contributing factor for the induction of Dengue Hemorrhagic Fever...

["Molecular Biology","Virology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.2970
1,086 downloads
9,709 views

Importance Case reports describe persistent erectile dysfunction (PED) associated with exposure to 5α-reductase inhibitors (5α-RIs). Clinical trial reports and the manufacturers’ full prescribing information (FPI) for finasteride and dutasteride state that risk...

["Dermatology","Epidemiology","Internal Medicine","Pharmacology","Urology"]
doi:10.7717/peerj.3020
51 downloads
525 views

It has previously been shown that domestic dogs and their household owners share bacterial populations, and that sharing of bacteria between humans is facilitated through the presence of dogs in the household. However, less is known regarding the bacterial communities...

["Microbiology","Veterinary Medicine","Dermatology"]
doi:10.7717/peerj.3075
37 downloads
263 views

Background Previous work demonstrated that individuals with higher levels of attachment anxiety are prone to increased binge eating (Alexander & Siegel, 2013). Given that our society rejects obese individuals and individuals with higher levels of attachment anxiety...

["Nutrition","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.3034
62 downloads
299 views

American trypanosomiasis is a chronic and endemic disease which affects millions of people. Trypanosoma cruzi, its causative agent, has a life cycle that involves complex morphological and functional transitions, as well as a variety of environmental conditions....

["Biochemistry","Genomics","Molecular Biology","Parasitology","Infectious Diseases"]
doi:10.7717/peerj.3017
107 downloads
675 views

Background The practice of feeding of diets containing raw animal products (RAP) to pets (dogs and cats) is discouraged by veterinary organizations and governmental public health organizations. Nevertheless, the practice of feeding RAP to pets is increasing in...

["Veterinary Medicine","Zoology","Nutrition"]
doi:10.7717/peerj.3031
46 downloads
247 views

Background To find the best individual chemotherapy for cancer patients, the efficacy of different chemotherapeutic drugs can be predicted by pretesting tumor samples in vitro via the chemotherapy-resistance (CTR)-Test®. Although drug combinations are widely used...

["Gynecology and Obstetrics","Oncology","Pharmacology"]
doi:10.7717/peerj.3030
92 downloads
538 views

Background The ergogenic effects of analgesic substances suggest that pain perception is an important regulator of work-rate during fatiguing exercise. Recent research has shown that endogenous inhibitory responses, which act to attenuate nociceptive input and...

["Neuroscience","Anaesthesiology and Pain Management","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.3028
59 downloads
261 views

Background Nowadays, the number of obese people in the world has reached alarming proportions. During the expansion of adipose tissue, a number of functions such as activation and release of cytokines and hormones may be affected. This leads the body to a pro-inflammatory...

["Diabetes and Endocrinology","Nutrition"]
doi:10.7717/peerj.2967
53 downloads
271 views

Background The macro environment we live in projects what we can achieve and how we behave, and in turn, shapes our health in complex ways. Policymaking will benefit from insights into the mechanisms underlying how national socioeconomic context affects health....

["Epidemiology","Global Health","Public Health","Statistics"]
doi:10.7717/peerj.3053
68 downloads
1,206 views

Background Resilience of midsole material and the upper structure of the shoe are conceptual characteristics that can interfere in running biomechanics patterns. Artificial intelligence techniques can capture features from the entire waveform, adding new perspective...

["Bioengineering","Kinesiology"]
doi:10.7717/peerj.3026
99 downloads
709 views

The past two decades have brought many important advances in our understanding of the hereditary susceptibility to cancer. Numerous studies have provided convincing evidence that identification of germline mutations associated with hereditary cancer syndromes can...

["Genomics","Oncology","Medical Genetics"]
doi:10.7717/peerj.3046
42 downloads
331 views

Introduction There is much literature devoted to the problem of drug resistance and decreased susceptibility of fungi to commonly used antifungals. Aim To analyze drug susceptibility of Candida albicans and non-Candida albicans strains isolated from the hands of...

["Microbiology","Mycology","Drugs and Devices","Public Health"]
doi:10.7717/peerj.3038

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