Peer-reviewed Articles - Medicine

32 downloads
233 views

Helicobacter pylori requires genetic agility to infect new hosts and establish long-term colonization of changing gastric environments. In this study, we analyzed H. pylori genetic adaptation in the Mongolian gerbil model. This model is of particular interest because...

["Microbiology","Infectious Diseases"]
doi:10.7717/peerj.4803
35 downloads
754 views

Background Epidemiologic data supporting the epilepsy–asthma association are insufficient. Therefore, we examined this association in this study. Methods By using claims data from the National Health Insurance Research Database (Taiwan), we executed a retrospective...

["Epidemiology","Immunology","Internal Medicine","Neurology"]
doi:10.7717/peerj.4792
27 downloads
143 views

Introduction Ureteropelvic junction obstruction (UPJO) is a common congenital anomaly leading to varying degrees of hydronephrosis (HN), ranging from no apparent effect on the renal function to atrophy. Evaluation of these children is based on Diuretic Renal Scintigraphy...

["Nephrology","Pediatrics","Radiology and Medical Imaging","Urology"]
doi:10.7717/peerj.4791
31 downloads
169 views

Lesion of the dopaminergic neurons of the nigrostriatal system is a key feature of Parkinson’s disease (PD). Alpha-synuclein is a protein that is a major component of Lewy bodies, histopathological hallmarks of PD, and is involved in regulation of dopamine (DA)...

["Developmental Biology","Neuroscience","Neurology","Pathology"]
doi:10.7717/peerj.4779
45 downloads
208 views

Diabetic retinopathy (DR) is the most common chronic complication of diabetes. It can cause impaired vision and even blindness. However, the pathological mechanism of DR is still unknown. In the present study, we use bioinformatic analysis to reveal the pathological...

["Bioinformatics","Ophthalmology"]
doi:10.7717/peerj.4762
39 downloads
168 views

Occlusive artery disease (CAD) is the leading cause of death worldwide. Bypass graft surgery remains the most prevalently performed treatment for occlusive arterial disease, and veins are the most frequently used conduits for surgical revascularization. However,...

["Bioinformatics","Cell Biology","Genetics","Genomics","Cardiology"]
doi:10.7717/peerj.4704
77 downloads
290 views

Background Breast cancer stem cells (BCSCs) are associated with the invasion of breast cancer. In recent years, studies have demonstrated different phenotypes among BCSCs. Furthermore, BCSCs of diverse phenotypes are present at different tumour sites and different...

["Cell Biology","Oncology"]
doi:10.7717/peerj.4805
73 downloads
175 views

Background The majority of past work on athletes’ use of psychological skills and techniques (PSTs) has adopted a variable-centered approach in which the statistical relations among study variables are averaged across a sample. However, variable-centered-analyses...

["Kinesiology","Psychiatry and Psychology"]
doi:10.7717/peerj.4778
57 downloads
284 views

The blood–brain barrier (BBB), an interface between the systemic circulation and the nervous system, can be a target of cytokines in inflammatory conditions. Pro-inflammatory cytokines tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) induce damage in...

["Cell Biology","Neuroscience","Pharmacology"]
doi:10.7717/peerj.4774
114 downloads
1,070 views

Outbreaks of coral diseases continue to reduce global coral populations. In the Caribbean, yellow band is a severe and wide-spread disease that commonly affects corals of the Orbicella spp. complex, significantly impeding coral reproduction, and hindering the natural...

["Marine Biology","Zoology","Epidemiology"]
doi:10.7717/peerj.4800
93 downloads
343 views

Background Alzheimer’ disease (AD) is an ultimately fatal degenerative brain disorder that has an increasingly large burden on health and social care systems. There are only five drugs for AD on the market, and no new effective medicines have been discovered for...

["Bioinformatics","Computational Biology","Cognitive Disorders"]
doi:10.7717/peerj.4756
77 downloads
445 views

Background Tibial stress fracture (TSF) is a common injury in basketball players. This condition has been associated with high tibial shock and impact loading, which can be affected by running speed, footwear condition, and footstrike pattern. However, these relationships...

["Bioengineering","Kinesiology"]
doi:10.7717/peerj.4753
54 downloads
326 views

Background Knee osteoarthritis (OA) patients often suffer joint pain and stiffness, which contributes to negative changes in body composition, strength, physical performance (function), physical activity and health-related quality of life. To reduce these symptoms...

["Kinesiology"]
doi:10.7717/peerj.4738
67 downloads
370 views

An estimated two billion people worldwide currently suffer from micronutrient malnutrition, and almost one billion are calorie deficient. Providing adequate nutrition is a growing global challenge. Seafood is one of the most important sources of both protein and...

["Aquaculture, Fisheries and Fish Science","Global Health","Nutrition","Coupled Natural and Human Systems","Natural Resource Management"]
doi:10.7717/peerj.4733
73 downloads
270 views

Background Using DNA microarrays, we previously identified 451 genes expressed in 19 different human tissues. Although ubiquitously expressed, the variable expression patterns of these “housekeeping genes” (HKGs) could separate one normal human tissue type from...

["Bioinformatics","Computational Biology","Genomics","Oncology","Medical Genetics"]
doi:10.7717/peerj.4719

Refine by manuscript type

Top subject areas - Articles

Top subject areas - People

View all subject areas