Peer-reviewed Articles - Medicine

48 downloads
130 views

Background Long non-coding RNAs (lncRNAs) can function as competing endogenous RNAs (ceRNAs) to interact with miRNAs to regulate target genes and promote cancer initiation and progression. The expression of lncRNAs and miRNAs can be epigenetically regulated. The...

["Bioinformatics","Oncology","Computational Science"]
doi:10.7717/peerj.7456
37 downloads
120 views

Background Medical institutions worldwide have not reached a consensus on what surgery is the most advisable for pulmonary typical carcinoid (TC) patients at the localized stage. This research focuses on exploring whether wedge resection or segmental resection...

["Oncology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.7519
33 downloads
146 views

Background The association between asthma (AS), allergic rhinitis (AR) and oral diseases remains inconclusive in adults. AS and AR often coexist. However, studies that investigate AS, AR together and their association with oral diseases are scarce. Methods Data...

["Allergy and Clinical Immunology","Dentistry","Epidemiology","Otorhinolaryngology","Public Health"]
doi:10.7717/peerj.7643
41 downloads
211 views

Background We assessed histopathological changes of ovaries and uterus in female rats subjected to different jumping exercise intensities combined with honey supplementation at one g/kg body weight/day. Methods A total of 72 rats were divided into six groups, 12...

["Anatomy and Physiology","Kinesiology","Nutrition","Public Health","Women\u2019s Health"]
doi:10.7717/peerj.7646
128 downloads
134 views

Background Hepatitis B virus (HBV) reactivation with a hepatitis flare is a common complication in lymphoma patients treated with immunotherapy and/or chemotherapy. Anti-HBV prophylaxis is suggested for non-Hodgkin lymphoma (NHL) patients undergoing rituximab therapy,...

["Gastroenterology and Hepatology","Hematology","Oncology"]
doi:10.7717/peerj.7481
204 downloads
184 views

Triple-negative breast cancer (TNBC) is a particular subtype of breast malignant tumor with poorer prognosis than other molecular subtypes. Previous studies have demonstrated that some abnormal expression of non-coding RNAs including microRNAs (miRNAs) and long...

["Bioinformatics","Genomics","Oncology"]
doi:10.7717/peerj.7522
115 downloads
120 views

Background The pro-tumoral action of the cluster of differentiation 147 (CD147), which is associated with the chemotherapy resistance of lung adenocarcinoma, is partly due to accelerated tumor cell glycolysis. 18F-fluorodeoxyglucose positron emission tomography...

["Oncology","Radiology and Medical Imaging","Respiratory Medicine"]
doi:10.7717/peerj.7635
127 downloads
157 views

Background Injection of adipose-derived stem cells (ASCs) is a promising treatment for facial contour deformities. However, its treatment mechanisms remain largely unknown. The study aimed to explain the molecular mechanisms of adipogenic differentiation from ASCs...

["Bioinformatics","Computational Biology","Genomics","Surgery and Surgical Specialties"]
doi:10.7717/peerj.7544
131 downloads
180 views

Hepatocellular carcinoma (HCC) is a common yet deadly form of malignant cancer. However, the specific mechanisms involved in HCC diagnosis have not yet fully elucidated. Herein, we screened four publically available Gene Expression Omnibus (GEO) expression profiles...

["Bioinformatics","Gastroenterology and Hepatology"]
doi:10.7717/peerj.7619
127 downloads
144 views

Background Alzheimer’s disease (AD) is the primary cause of dementia in the elderly. The imbalance between production and clearance of amyloid β (Aβ) is a very early, often initiating factor in AD. Dendrobium nobile Lindl. alkaloids (DNLA) extracted from a Chinese...

["Neuroscience","Drugs and Devices","Evidence Based Medicine","Pharmacology"]
doi:10.7717/peerj.7627
78 downloads
144 views

Background The total number of nephrons has been measured mainly from post-mortem studies and only in selected populations. Data from living subjects are scanty, and direct comparisons among different glomerular diseases are lacking. The present work exploits modern...

["Nephrology","Pathology"]
doi:10.7717/peerj.7640
182 downloads
189 views

Objective This study aims to identify effective gene networks and biomarkers to predict response and prognosis for HER2-negative breast cancer patients who received sequential taxane-anthracycline neoadjuvant chemotherapy. Materials and Methods Transcriptome data...

["Cell Biology","Genetics","Oncology","Women\u2019s Health"]
doi:10.7717/peerj.7515
124 downloads
181 views

Objective Aloperine (ALO), an alkaloid isolated from the leaves of Sophora alopecuroides, has been suggested to exhibit anti-inflammatory and anti-tumor properties and is traditionally used to treat various human diseases, including cancer. However, limited information...

["Molecular Biology","Oncology","Pharmacology"]
doi:10.7717/peerj.7652
194 downloads
276 views

Osteoarthritis (OA) is the most common motor system disease in aging people, characterized by matrix degradation, chondrocyte death, and osteophyte formation. OA etiology is unclear, but long noncoding RNAs (lncRNAs) that participate in numerous pathological and...

["Genetics","Genomics","Orthopedics","Ethical Issues"]
doi:10.7717/peerj.7491
110 downloads
230 views

Cognitive impairment often involves the decreased expression or hypofunction of alpha 7-type nicotinic acetylcholine receptors (α7 nAChRs). Agonists or positive allosteric modulators (PAMs) of α7 nAChRs are known to be potential treatments for dementias, different...

["Biophysics","Neuroscience","Pharmacology"]
doi:10.7717/peerj.7542

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