Peer-reviewed Articles - Medicine

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Lower urinary tract symptoms (LUTS) are common complaints in the adult male population and have a negative affect in the quality of life and represent an economic burden for the healthcare system worldwide. The International Prostatism Symptom Score (IPSS) is a...

["Geriatrics","Public Health","Surgery and Surgical Specialties","Urology"]
doi:10.7717/peerj.9039
2 downloads
2 views

Background Gastric cancer is one of the most common malignant cancers worldwide. Despite substantial developments in therapeutic strategies, the five-year survival rate remains low. Therefore, novel biomarkers and therapeutic targets involved in the progression...

["Bioinformatics","Molecular Biology","Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.9123
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Background Research has shown that Poly-ADP-ribose polymerases 1 (PARP-1) is a potential therapeutic target in the clinical treatment of breast cancer. An increasing number of studies have focused on the development of highly selective inhibitors that target PARP-1...

["Molecular Biology","Oncology","Pharmacology","Computational Science"]
doi:10.7717/peerj.9241
35 downloads
129 views

Background Nowadays, the most widely used types of wearable sensors in gait analysis are inertial sensors. The aim of the study was to assess the agreement between two different systems for measuring gait parameters (inertial sensor vs. electronic walkway) on healthy...

["Bioengineering","Kinesiology"]
doi:10.7717/peerj.8835
55 downloads
162 views

Background Benzalkonium chloride (BAK), commonly used in glaucoma treatment, is an eye drop preservative with dose-dependent toxicity. Previous studies have observed the multi-functional benefits of angiogenin (ANG) against glaucoma. In our study, we evaluated...

["Bioengineering","Drugs and Devices","Ophthalmology","Pharmacology"]
doi:10.7717/peerj.9084
31 downloads
105 views

Background To study the peculiarities of changes in creatinine concentration in blood serum of untrained men during the prolonged usage of training loads different in volume and intensity, and to determine the value of this biochemical marker for the assessment...

["Biochemistry","Anatomy and Physiology","Kinesiology","Statistics"]
doi:10.7717/peerj.9137
100 downloads
706 views

Background Human milk microbiota plays a role in the bacterial colonization of the neonatal gut, which has important consequences in the health and development of the newborn. However, there are few studies about the vertical transfer of bacteria from mother to...

["Bioinformatics","Microbiology","Pediatrics"]
doi:10.7717/peerj.9205
35 downloads
178 views

Background Stress reactivity can be different in women compared to men, which might consequently influence disease risk.Stress in women may also generate adverse physiological effects on their offspring during pregnancy or lactation. The objective of this study...

["Clinical Trials","Psychiatry and Psychology","Women\u2019s Health"]
doi:10.7717/peerj.9217
49 downloads
176 views

Introduction Retinoblastoma (RB) is one common pediatric malignant tumor with dismal outcomes. Heterogeneity of RB and subtypes of RB were identified but the association between the subtypes of RB and RB progression have not been fully investigated. Methods Four...

["Bioinformatics","Ophthalmology"]
doi:10.7717/peerj.8873
91 downloads
1,022 views

Vitiligo is a chronic asymptomatic disorder affecting melanocytes from the basal layer of the epidermis which leads to a patchy loss of skin color. Even though it is one of the neglected disease conditions, people suffering from vitiligo are more prone to psychological...

["Bioinformatics","Computational Biology","Dermatology","Computational Science"]
doi:10.7717/peerj.9119
46 downloads
200 views

Enterococcus is a genus of Gram-positive bacteria that are commensal to the gastrointestinal tracts of humans but some species have been increasingly implicated as agents of nosocomial infections. The increase in infections and the spread of antibiotic-resistant...

["Genomics","Taxonomy","Virology","Infectious Diseases"]
doi:10.7717/peerj.9171
41 downloads
166 views

Background Avian pathogenic Escherichia coli (APEC), an important extraintestinal pathogenic E. coli, causes colibacillosis, an acute and mostly systemic disease involving multiple organ lesions such as meningitis. Meningitis-causing APEC can invade the host central...

["Bioinformatics","Microbiology","Veterinary Medicine","Infectious Diseases"]
doi:10.7717/peerj.9172
46 downloads
136 views

Background Anaplastic thyroid carcinoma (ATC) is a rare malignant tumor with a poor prognosis. However, there is no useful clinical prognostic predictive tool for ATC so far. Our study identified risk factors for survival of ATC and created a reliable nomogram...

["Bioinformatics","Diabetes and Endocrinology","Internal Medicine","Metabolic Sciences"]
doi:10.7717/peerj.9173
52 downloads
147 views

Background Bisphosphonate therapy has become a popular treatment for osteoporosis, Paget’s disease, multiple myeloma, osteogenesis imperfecta, myocardial infarction, and cancer despite its serious side effects. Bisphosphonate-induced molecular signaling changes...

["Biochemistry","Biotechnology","Cell Biology","Pathology","Pharmacology"]
doi:10.7717/peerj.9202
31 downloads
93 views

Background Sublobar resection (SLR) and radiofrequency ablation (RFA) are the two minimally invasive procedures performed for treating stage I non-small cell lung cancer (NSCLC). This study aimed to compare SLR and RFA for the treatment of stage I NSCLC using the...

["Oncology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.9228

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