Peer-reviewed Articles - Medicine

Background The annual global deaths from viral hepatitis is 1.4 million. Pakistan has the second highest burden of hepatitis C in the world. There is dire need to evaluate the response of new direct acting antivirals for the treatment of hepatitis C patients in...

["Virology","Gastroenterology and Hepatology"]
doi:10.7717/peerj.4853

Background Among combat sports, Judo and Brazilian Jiu-Jitsu (BJJ) present elevated physical fitness demands from the high-intensity intermittent efforts. However, information regarding how metabolic and neuromuscular physical fitness is associated with technical-tactical...

["Anatomy and Physiology","Kinesiology"]
doi:10.7717/peerj.4851

Purpose A literature review is presented that aims to summarize and compare current methods to evaluate sleep. Methods Current sleep assessment methods have been classified according to different criteria; e.g., objective (polysomnography, actigraphy…) vs. subjective...

["Global Health","Neurology"]
doi:10.7717/peerj.4849

Genotypic drug resistance testing has been an integral part of the clinical management of HIV patients for almost 20 years, not only assisting treatment choices but also informing drug development. Accurate estimations on the worldwide circulation of drug resistance...

["Virology","Epidemiology","Global Health","HIV","Statistics"]
doi:10.7717/peerj.4848
7 downloads
73 views

When the task is reading nonwords aloud, skilled adult readers are very variable in the responses they produce: a nonword can evoke as many as 24 different responses in a group of such readers. Why is nonword reading so variable? We analysed a large database of...

["Cognitive Disorders","Psychiatry and Psychology","Computational Science"]
doi:10.7717/peerj.4879
17 downloads
59 views

Background To treat skin color disorders, such as vitiligo or burns, melanocytes are transplanted for tissue regeneration. However, melanocyte distribution in the human body varies with age and location, making it difficult to select the optimal donor skin to achieve...

["Bioengineering","Biotechnology","Dermatology"]
doi:10.7717/peerj.4815
32 downloads
77 views

Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals that has caused tremendous economic losses worldwide. In this study, we designed a chimeric nanoparticles (CNPs) vaccine that displays the predominant epitope of the serotype O...

["Bioengineering","Biotechnology","Immunology"]
doi:10.7717/peerj.4823
28 downloads
82 views

Estimating the depth of anaesthesia (DoA) in operations has always been a challenging issue due to the underlying complexity of the brain mechanisms. Electroencephalogram (EEG) signals are undoubtedly the most widely used signals for measuring DoA. In this paper,...

["Anesthesiology and Pain Management","Statistics","Computational Science"]
doi:10.7717/peerj.4817
13 downloads
161 views

Background Ceratonia siliqua pods (carob) have been nominated to control the high blood glucose of diabetics. In Yemen, however, its antihyperglycemic activity has not been yet assessed. Thus, this study evaluated the in vitro inhibitory effect of the methanolic...

["Diabetes and Endocrinology","Pharmacology"]
doi:10.7717/peerj.4788
18 downloads
179 views

Background For the diagnosis of attention-deficit/hyperactivity disorder (ADHD), the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) proposes that adherence to six symptoms in either group (inattention and hyperactivity/impulsivity) will lead to the...

["Psychiatry and Psychology","Statistics"]
doi:10.7717/peerj.4820
24 downloads
134 views

Background Concomitant drug administration is a general phenomenon in patients with chronic diseases such as diabetes mellitus. Among the currently available oral antidiabetic drugs, gliclazide is a commonly prescribed drug considering its multiple benefits in...

["Diabetes and Endocrinology","Pharmacology"]
doi:10.7717/peerj.4798
35 downloads
243 views

Introduction The long-term use of benzodiazepines (BZD) and z-drugs in older populations is associated with a variety of sociodemographic and health-related factors. Recent studies reported that long-term BZD and z-drugs use is associated with increased age, female...

["Geriatrics","Pharmacology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.4614
27 downloads
184 views

Mitochondria are small, energy-producing structures vital to the energy needs of the body. Genetic mutations cause mitochondria to fail to produce the energy needed by cells and organs which can cause severe disease and death. These genetic mutations are likely...

["Genetics","Internal Medicine","Neurology","Medical Genetics"]
doi:10.7717/peerj.4790
52 downloads
146 views

Several personality factors have been implicated in vulnerability to addiction by impacting learning and decision making. One such factor is intolerance of uncertainty (IU), the tendency to perceive uncertain situations negatively and avoid them. Conditioned place...

["Psychiatry and Psychology"]
doi:10.7717/peerj.4775
53 downloads
310 views

Using hypothetical scenarios, we provided participants with potential opening statements to a conflict discussion that varied on I/you language and communicated perspective. Participants rated the likelihood that the recipient of the statement would react in a...

["Psychiatry and Psychology","Legal Issues"]
doi:10.7717/peerj.4831

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