Peer-reviewed Articles - Medicine

41 downloads
219 views

Drug repositioning (i.e., drug repurposing) is the process of discovering new uses for marketed drugs. Historically, such discoveries were serendipitous. However, the rapid growth in electronic clinical data and text mining tools makes it feasible to systematically...

["Bioinformatics","Clinical Trials","Drugs and Devices","Oncology","Statistics"]
doi:10.7717/peerj.3154
23 downloads
159 views

The literature indicates the best vibration positions and frequencies on the human body where tactile information is transmitted. However, there is a lack of knowledge about how to combine tactile stimuli for navigation. The aim of this study is to compare different...

["Kinesiology","Psychiatry and Psychology","Human-Computer Interaction"]
doi:10.7717/peerj.3082
20 downloads
249 views

Objective The purpose of this study was to assess the effects of age, body condition score (BCS) and muscle condition score (MCS) on indirect radial and coccygeal Doppler systolic arterial blood pressure (SAP) measurements in dogs. Methods Sixty-two privately-owned...

["Veterinary Medicine","Internal Medicine"]
doi:10.7717/peerj.3101
27 downloads
199 views

Background and Objective The Korean version of the EQ-5D-Y was launched in 2015 by the EuroQol group. Currently, there is no HRQOL data obtained by using the EQ-5D-Y in Korea. This study aimed to measure health-related quality of life of Korean elementary school...

["Epidemiology","Global Health","Health Policy","Pediatrics","Public Health"]
doi:10.7717/peerj.3115
31 downloads
213 views

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape...

["Cell Biology","Immunology","Pharmacology"]
doi:10.7717/peerj.3108
41 downloads
197 views

Background While evidence highlights the detrimental health consequences of adverse working conditions, effect sizes vary by the stressor examined. In this study, we aimed to explore the differential effects various constellations of job demands have on prevalent...

["Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.3106
134 downloads
846 views

The patella is a sesamoid bone located in the major extensor tendon of the knee joint, in the hindlimb of many tetrapods. Although numerous aspects of knee morphology are ancient and conserved among most tetrapods, the evolutionary occurrence of an ossified patella...

["Evolutionary Studies","Palaeontology","Zoology","Anatomy and Physiology"]
doi:10.7717/peerj.3103
25 downloads
132 views

Background The promising postsurgical weight loss and remission of type 2 diabetes (T2D) from bariatric surgery can be attributed to modified eating physiology after surgical procedures. We sought to investigate the changes in the parameters of consumption behaviors...

["Diabetes and Endocrinology","Gastroenterology and Hepatology","Psychiatry and Psychology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3090
36 downloads
258 views

Background Cartilage tissue engineering is a fast-evolving field of biomedical engineering, in which the chondrocytes represent the most commonly used cell type. Since research in tissue engineering always consumes a lot of cells, simple and cheap isolation methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.3079
50 downloads
197 views

Background Zika virus (ZIKV) transmission has been reported in 67 countries/territories in the Oceania region and the Americas since 2015, prompting the World Health Organization (WHO) to declare ZIKV as a Public Health Emergency of International Concern in February...

["Mathematical Biology","Virology","Epidemiology","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3015
27 downloads
129 views

Background The Non-Recurrent Laryngeal Nerve (NRLN) is a rare embryologically-derived variant of the Recurrent Laryngeal Nerve (RLN). The presence of an NRLN significantly increases the risk of iatrogenic injury and operative complications. Our aim was to provide...

["Anatomy and Physiology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3012
30 downloads
192 views

Background This study evaluates two procedures for typing of Streptococcus agalactiae (group B streptococci; GBS) isolates, using retrospective typing data from the period 2010 to 2014 with a commercial latex agglutination test (latex test) and the Lancefield precipitation...

["Microbiology","Epidemiology","Infectious Diseases","Internal Medicine","Pediatrics"]
doi:10.7717/peerj.3105
53 downloads
363 views

Background Rheumatoid arthritis (RA) is a chronic auto-inflammatory disorder of joints. The present study aimed to identify the key genes in RA for better understanding the underlying mechanisms of RA. Methods The integrated analysis of expression profiling was...

["Bioinformatics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.3078
98 downloads
494 views

Background Gross dissection is a widespread method for studying animal anatomy, despite being highly destructive and time-consuming. X-ray computed tomography (CT) has been shown to be a non-destructive alternative for studying anatomical structures. However, in...

["Computational Biology","Zoology","Radiology and Medical Imaging"]
doi:10.7717/peerj.3039
83 downloads
490 views

Zika virus is a newly emergent mosquito-borne flavivirus that has caused recent large outbreaks in the new world, leading to dramatic increases in serious disease pathology including Guillain-Barre syndrome, newborn microcephaly, and infant brain damage. Although...

["Entomology","Virology","Global Health","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3096

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