Peer-reviewed Articles - Medicine

Background Diabetes is one of the major risk factors for peripheral arterial disease. In patients in whom surgery cannot be performed, cell therapy may be an alternative treatment. Since time is crucial for these patients, we propose the use of allogenic mesenchymal...

["Surgery and Surgical Specialties","Translational Medicine"]
doi:10.7717/peerj.3664

Background Although evolution is the driving force behind many of today’s major public health and agriculture issues, both journalists and scientific researchers often do not use the term “evolve” in discussions of these topics. Methods In a total of 1,066 articles...

["Evolutionary Studies","Public Health","Science and Medical Education","Science Policy"]
doi:10.7717/peerj.3639

Identification of appropriate reference genes (RGs) is critical to accurate data interpretation in quantitative real-time PCR (qPCR) experiments. In this study, we have utilised next generation RNA sequencing (RNA-seq) to analyse the transcriptome of a panel of...

["Genomics","Molecular Biology","Dermatology","Oncology","Medical Genetics"]
doi:10.7717/peerj.3631
23 downloads
182 views

The prevalence of Type II Diabetes (T2D) has been increasing and has become a disease of significant public health burden in Jordan. None of the previous genome-wide association studies (GWAS) have specifically investigated the Middle East populations. The Circassian...

["Genetics","Genomics","Diabetes and Endocrinology","Medical Genetics"]
doi:10.7717/peerj.3618
21 downloads
153 views

The cynomolgus macaque (Macaca fascicularis) is an extensively utilised nonhuman primate model for biomedical research due to its biological, behavioural, and genetic similarities to humans. Genomic information of cynomolgus macaque is vital for research in various...

["Bioinformatics","Genomics","Zoology","Immunology"]
doi:10.7717/peerj.3566
34 downloads
207 views

Background The age of onset of substance use (OSU) as well as the coping strategies (CS) influence both the development and the course of Substance Use Disorders (SUD). We aim to examine the differences in the CS applied to deal with treatment in men with SUD,...

["Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.3660
30 downloads
88 views

Objective This study aims to compare the sensitivity of dual phase (non-contrast and arterial) versus single phase (arterial) CT for detection of hyper-functioning parathyroid glands in patients with primary hyperparathyroidism. Methods The CT scans of thirty-two...

["Diabetes and Endocrinology","Radiology and Medical Imaging"]
doi:10.7717/peerj.3586
37 downloads
185 views

Objective Circulating endothelial progenitor cells (EPCs) correlate negatively with obesity. Previous studies have shown that exercise significantly restores circulating EPC levels in obese people; however, the underlying mechanisms have not been elucidated. Recently,...

["Neuroscience","Cardiology","Clinical Trials","Nutrition"]
doi:10.7717/peerj.3669
9 downloads
92 views

Background Hypoxia-inducible factor (HIF)-1 is involved in the regulation of hypoxic preconditioning in cardiomyocytes. Under hypoxic conditions, HIF-1α accumulates and is translocated to the nucleus, where it forms an active complex with HIF-1β and activates transcription...

["Cell Biology","Anaesthesiology and Pain Management","Cardiology"]
doi:10.7717/peerj.3662
10 downloads
164 views

Objective The trabecular meshwork (TM) is the primary substrate of outflow resistance in glaucomatous eyes. Repopulating diseased TM with fresh, functional TM cells might be a viable therapeutic approach. Decellularized TM scaffolds have previously been produced...

["Bioengineering","Biotechnology","Ophthalmology"]
doi:10.7717/peerj.3629
56 downloads
278 views

Background Psychological factors have been suggested to have an influence in Atrial Fibrillation (AF) onset, progression, severity and outcomes, but their role is unclear and mainly focused on anxiety and depression. Methods A systematic electronic search had been...

["Cardiology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.3537
23 downloads
280 views

Background The cause−effect relation between periodontal inflammatory disease (PID) and Parkinson’s disease (PD) remains uncertain. The purpose of our study was to investigate the association between PID and PD. Methods We conducted a retrospective matched-cohort...

["Dentistry","Epidemiology","Neurology","Public Health"]
doi:10.7717/peerj.3647
40 downloads
385 views

Background The problem of coping with stress is an important one in the context of development and persistence of alcohol dependence. In the literature to date very little attention has been paid to coping patterns construed as a configuration of specific coping...

["Psychiatry and Psychology"]
doi:10.7717/peerj.3576
53 downloads
419 views

Introduction Our study aims at identifying and quantifying the relationship between the cold and heat exposure and the risk of cardiovascular mortality through a systematic review and meta-analysis. Material and Methods A systematic review and meta-analysis were...

["Cardiology","Public Health"]
doi:10.7717/peerj.3574
40 downloads
694 views

Aim To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. Methods The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical...

["Clinical Trials","Gastroenterology and Hepatology","Internal Medicine"]
doi:10.7717/peerj.3654

Top subject areas - Articles

Top subject areas - People

View all subject areas