Peer-reviewed Articles - Medicine

Background/Aim Strabismus is a common condition with misalignment between two eyes that may lead to decrease of visual acuity, lack of binocularity, and diplopia. It is caused by heterogeneous environmental and genetic risk factors. Our previous research has identified...

["Genetics","Genomics","Ophthalmology","Medical Genetics"]
doi:10.7717/peerj.3935

Background The study objective was to investigate and synthesize available evidence relating to the psychological health of Emergency Dispatch Centre (EDC) operatives, and to identify key stressors experienced by EDC operatives. Methods Eight electronic databases...

["Emergency and Critical Care","Psychiatry and Psychology"]
doi:10.7717/peerj.3735
7 downloads
84 views

Background The present study investigated differences in reading and spelling outcomes in Dutch and English as a second language (ESL) in adolescents with a high familial risk of dyslexia, of whom some have developed dyslexia (HRDys) while others have not (HRnonDys),...

["Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.3895
9 downloads
388 views

Background Dual energy X-ray absorptiometry (DXA) is a commonly used instrument for analysing segmental body composition (BC). The information from the scan guides the clinician in the treatment of conditions such as obesity and can be used to monitor recovery...

["Drugs and Devices","Epidemiology","Kinesiology","Nutrition","Radiology and Medical Imaging"]
doi:10.7717/peerj.3880
14 downloads
122 views

Tumor-infiltrating lymphocytes (TILs) are associated with better clinical outcomes in many tumors. TILs represent a cell-mediated immune response against the carcinoma. CD8+ TILs are a crucial component of cell-mediated immunity. The significance of CD8+ TILs has...

["Immunology","Oncology","Urology"]
doi:10.7717/peerj.3921
19 downloads
134 views

Objective The objective of this study was to explore the differences in upper airway morphology between positional (POSA) and non-positional (NPOSA) obstructive sleep apnea. Methods This retrospective study enrolled 75 patients (45 NPOSA and 30 POSA) who underwent...

["Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3918
75 downloads
798 views

Objectives Compare the immediate effects of a Neurodynamic Mobilization (NM) treatment or foam roller (FR) treatment after DOMS. Design Double blind randomised clinical trial. Setting The participants performed 100 drop jumps (5 sets of 20 repetitions, separated...

["Clinical Trials","Evidence Based Medicine","Geriatrics","Nursing","Rheumatology"]
doi:10.7717/peerj.3908
28 downloads
243 views

In the context of a hunt for a postulated hormone that is tissue-mass inhibiting and reproductively associated, there is described probable relatedness to a granin protein. A 7–8 kDa polypeptide candidate (gels/MS) appeared in a bioassay-guided fractionation campaign...

["Biochemistry","Cell Biology","Diabetes and Endocrinology","Neurology"]
doi:10.7717/peerj.3833
23 downloads
165 views

Background Cocaine use disorder (CUD) is a complex health condition, especially when it is accompanied by comorbid psychiatric disorders (dual diagnosis). Dual diagnosis is associated with difficulties in the stratification and treatment of patients. One of the...

["Cognitive Disorders","Neurology","Psychiatry and Psychology"]
doi:10.7717/peerj.3926
16 downloads
121 views

Background In late 2015, cut-off points were published for foveal thickness to diagnose diabetic macular oedema taking into account the presence of intraretinal fluid using optical coherence tomography (OCT) in primary care patients (90 µm in the presence of intraretinal...

["Diabetes and Endocrinology","Epidemiology","Evidence Based Medicine","Ophthalmology","Public Health"]
doi:10.7717/peerj.3922
23 downloads
169 views

Background Although spermatozoa with normal morphology are assumed to have uniform fertilization ability, recent data show that even normal spermatozoa have considerable variation in their head shape which is associated with differences in fertilization ability....

["Cell Biology","Developmental Biology","Andrology"]
doi:10.7717/peerj.3913
43 downloads
207 views

Background The interaction between influenza virus and the host response to infection clearly plays an important role in determining the outcome of infection. While much is known on the participation of inflammation on the pathogenesis of severe A (H1N1) pandemic...

["Global Health","Infectious Diseases","Public Health"]
doi:10.7717/peerj.3915
26 downloads
175 views

Background Parkinson’s disease (PD) is a disorder characterized by dopaminergic neuron programmed cell death. The etiology of PD remains uncertain—some cases are due to selected genes associated with familial heredity, others are due to environmental exposure to...

["Microbiology","Neuroscience","Infectious Diseases"]
doi:10.7717/peerj.3823
38 downloads
188 views

Background Local residual and recurrent nasopharyngeal carcinoma (NPC) generally shows treatment failure after standard radiotherapy with or without concurrent chemotherapy. Whether endoscopic nasopharyngectomy might provide an additional therapeutic advantage...

["Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.3912
81 downloads
218 views

Human papillomavirus (HPV) is the leading cause of cervical cancer. Urine-based HPV testing offers a simple and non-invasive method because of its increasing acceptance. A total of 164 pairs of cervical swab and urine samples from Thai women who underwent cervical...

["Virology","Infectious Diseases","Oncology","Women\u2019s Health"]
doi:10.7717/peerj.3910

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