Peer-reviewed Articles - Medicine

23 downloads
287 views

The past two decades have brought many important advances in our understanding of the hereditary susceptibility to cancer. Numerous studies have provided convincing evidence that identification of germline mutations associated with hereditary cancer syndromes can...

["Genomics","Oncology","Medical Genetics"]
doi:10.7717/peerj.3046
13 downloads
174 views

Introduction There is much literature devoted to the problem of drug resistance and decreased susceptibility of fungi to commonly used antifungals. Aim To analyze drug susceptibility of Candida albicans and non-Candida albicans strains isolated from the hands of...

["Microbiology","Mycology","Drugs and Devices","Public Health"]
doi:10.7717/peerj.3038
83 downloads
859 views

Background Illusions that alter perception of the body provide novel opportunities to target brain-based contributions to problems such as persistent pain. One example of this, mirror therapy, uses vision to augment perceived movement of a painful limb to treat...

["Neuroscience","Anaesthesiology and Pain Management","Drugs and Devices","Human-Computer Interaction"]
doi:10.7717/peerj.3023
31 downloads
238 views

In legged terrestrial locomotion, the duration of stance phase, i.e., when limbs are in contact with the substrate, is positively correlated with limb length, and negatively correlated with the metabolic cost of transport. These relationships are well documented...

["Evolutionary Studies","Zoology","Anatomy and Physiology","Kinesiology"]
doi:10.7717/peerj.3008
19 downloads
144 views

Interstitial lung disease (ILD) is a severe extra-articular manifestation of rheumatoid arthritis (RA) that is well-defined as a chronic systemic autoimmune disease. A proportion of patients with RA-associated ILD (RA-ILD) develop pulmonary fibrosis (PF), resulting...

["Immunology","Respiratory Medicine","Rheumatology","Statistics"]
doi:10.7717/peerj.3021
26 downloads
130 views

Background The outcomes of the physician-patient discussion intervene in the satisfaction of cardiovascular disease risk patients. Adherence to treatment, provision of continuous care, clinical management of the illness and patients’ adjustment are influenced by...

["Cardiology","Public Health","Science and Medical Education"]
doi:10.7717/peerj.2983
56 downloads
436 views

Background Colorectal cancer (CRC) is one of the leading cancers worldwide. Several studies have performed microarray data analyses for cancer classification and prognostic analyses. Microarray assays also enable the identification of gene signatures for molecular...

["Bioinformatics","Mathematical Biology","Molecular Biology","Oncology","Statistics"]
doi:10.7717/peerj.3003
34 downloads
295 views

Background Interleukin (IL)-17 produced by mainly T helper 17 (Th17) cells may play an important destructive role in chronic periodontitis (CP). Thus, anti-inflammatory cytokines, such as IL-35, might have a beneficial effect in periodontitis by inhibiting differentiation...

["Dentistry","Immunology"]
doi:10.7717/peerj.2999
24 downloads
109 views

Background Paroxysmal sympathetic hyperactivity (PSH) results and aggravates in secondary brain injury, which seriously affects the prognosis of severe traumatic brain injury patients. Although several studies have focused on the treatment of PSH, few have concentrated...

["Drugs and Devices","Emergency and Critical Care","Neurology"]
doi:10.7717/peerj.2986
54 downloads
272 views

Background Dental anxiety is a widespread problem in many populations. This problem can be a barrier to dental care and may lead to poor oral health. Dental anxiety may be related to psychological status. Aims The aim of the present study was to assess the levels...

["Dentistry","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.2978
44 downloads
775 views

Modafinil (2-((diphenylmethyl)sulfinyl)acetamide), a selective dopamine and norepinephrine transporter inhibitor, is most commonly prescribed for narcolepsy but has gained recent interest for treating a variety of disorders. Zebrafish (Danio rerio) are becoming...

["Animal Behavior","Aquaculture, Fisheries and Fish Science","Neuroscience","Pharmacology"]
doi:10.7717/peerj.2994
77 downloads
429 views

Background There is a high prevalence of non-specific shoulder pain associated with upper limb functional limitations in older adults. The purpose of this study was to determine the minimal clinically important differences (MCID) of grip strength and pressure pain...

["Geriatrics","Orthopedics","Rheumatology"]
doi:10.7717/peerj.2995
47 downloads
291 views

Background Several recent studies have shown that total scores on depressive symptom measures in a general population approximate an exponential pattern except for the lower end of the distribution. Furthermore, we confirmed that the exponential pattern is present...

["Epidemiology","Psychiatry and Psychology","Statistics"]
doi:10.7717/peerj.2987
125 downloads
467 views

Background Manual anthropometric measurements are time-consuming and challenging to perform within acceptable intra- and inter-individual error margins in large studies. Three-dimensional (3D) laser body scanners provide a fast and precise alternative: within a...

["Anthropology","Anatomy and Physiology","Epidemiology","Public Health","Radiology and Medical Imaging"]
doi:10.7717/peerj.2980
61 downloads
520 views

Localized genomic variability is crucial for the ongoing conflicts between infectious microbes and their hosts. An understanding of evolutionary and adaptive patterns associated with genomic variability will help guide development of vaccines and antimicrobial...

["Microbiology","Dermatology"]
doi:10.7717/peerj.2959

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