Peer-reviewed Articles - Medicine

Maximakinin (MK), an amphibian peptide possessing the C-terminal sequence of bradykinin (BK), is a BK B2 receptor (B2R) agonist eliciting prolonged signaling. We reinvestigated this 19-mer for species-specific pharmacologic profile, in vivo confirmation of resistance...

["Cardiology","Pharmacology"]
doi:10.7717/peerj.2911

Foot problems are a major cause of morbidity and mortality in elephants, but are underreported due to difficulties in diagnosis, particularly of conditions affecting the bones and internal structures. Here we evaluate post-mortem computer tomographic (CT) scans...

["Veterinary Medicine","Pathology","Radiology and Medical Imaging"]
doi:10.7717/peerj.2877

Background Platinum-based agents are widely used in chemotherapy against solid tumors and insufficient intracellular drug accumulation is one of the leading causes of platinum resistance which is associated with poor survival of tumor patients. Thus, the detection...

["Cell Biology","Drugs and Devices","Oncology"]
doi:10.7717/peerj.2873
14 downloads
95 views

The successful navigation of social interactions depends on a range of cognitive faculties—including the ability to achieve joint attention with others to share information and experiences. We investigated the influence that intention monitoring processes have...

["Neuroscience","Cognitive Disorders","Human-Computer Interaction"]
doi:10.7717/peerj.2899
13 downloads
86 views

The effect of aging on the process of word encoding for fixated words and words presented to the right of the fixation point during the reading of sentences in Chinese was investigated with two disappearing text experiments. The results of Experiment 1 showed that...

["Cognitive Disorders","Ophthalmology","Psychiatry and Psychology"]
doi:10.7717/peerj.2897
17 downloads
98 views

Background Psychological disorders are common in diabetes mellitus (DM) patients, and the aim of this study was to estimate the prevalence of psychological distress and to determine the influence factors associated with psychological distress among DM patients...

["Diabetes and Endocrinology","Epidemiology","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.2869
10 downloads
44 views

Background Cryoelectrolysis is a new minimally invasive tissue ablation surgical technique that combines the ablation techniques of electrolytic ablation with cryosurgery. The goal of this study is to examine the hypothesis that electrolysis can take place in a...

["Biochemistry","Bioengineering","Biophysics","Oncology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.2810
54 downloads
231 views

This study investigated whether a yoga exercise intervention influenced the sustained attention and discrimination function in children with ADHD. Forty-nine participants (mean age = 10.50 years) were assigned to either a yoga exercise or a control group. Participants...

["Clinical Trials","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.2883
93 downloads
619 views

Recently, there has been a move encouraged by many stakeholders towards generating big, open data in many areas of research. One area where big, open data is particularly valuable is in research relating to complex heterogeneous disorders such as Autism Spectrum...

["Bioinformatics","Neuroscience","Psychiatry and Psychology"]
doi:10.7717/peerj.2880
32 downloads
106 views

Background One important aspect of subjective judgments about one’s well-being (i.e., subjective well-being: life satisfaction, positive affect, and negative affect) is that cultural features, such as, nationality seem to shape cognitive judgments about the “the...

["Pediatrics","Psychiatry and Psychology","Public Health"]
doi:10.7717/peerj.2868
17 downloads
112 views

The fibrosis that develops following laminectomy or discectomy often causes serious complications, and the proliferation of fibroblasts is thought to be the major cause of epidural fibrosis. 10-Hydroxycamptothecin (HCPT) has been proven to be efficient in preventing...

["Cell Biology","Orthopedics","Pharmacology","Histology"]
doi:10.7717/peerj.2858
46 downloads
335 views

The ostrich is a highly cursorial bipedal land animal with a permanently elevated metatarsophalangeal joint supported by only two toes. Although locomotor kinematics in walking and running ostriches have been examined, these studies have been largely limited to...

["Animal Behavior","Bioengineering","Anatomy and Physiology","Kinesiology"]
doi:10.7717/peerj.2857
44 downloads
141 views

Background Electrical stimulation (ES) has been successfully used to treat bone defects clinically. Recently, both cellular and molecular approaches have demonstrated that ES can change cell behavior such as migration, proliferation and differentiation. Methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.2821
178 downloads
391 views

Background Accumulating evidence indicates interactions between human milk composition, particularly sugars (human milk oligosaccharides or HMO), the gut microbiota of human infants, and behavioral effects. Some HMO secreted in human milk are unable to be endogenously...

["Food Science and Technology","Microbiology","Gastroenterology and Hepatology","Nutrition","Pediatrics"]
doi:10.7717/peerj.2876
32 downloads
191 views

Background Liver disease has become an important cause of morbidity and mortality even in those HIV-infected individuals who are devoid of hepatitis virus co-infection. The aim of this study was to evaluate the degree of hepatic fibrosis and the role of associated...

["Gastroenterology and Hepatology","HIV","Public Health"]
doi:10.7717/peerj.2867

Top subject areas - Articles

Top subject areas - People

View all subject areas