Peer-reviewed Articles - Medicine

21 downloads
678 views

We comment on Eichstaedt et al.’s (2015a) claim to have shown that language patterns among Twitter users, aggregated at the level of US counties, predicted county-level mortality rates from atherosclerotic heart disease (AHD), with “negative” language being associated...

["Epidemiology","Health Policy","Psychiatry and Psychology","Public Health","Statistics"]
doi:10.7717/peerj.5656
16 downloads
50 views

Objective The benefits of IL-35 treatment have been verified in multiple animal models of diseases, while its influence on T cells immunity under normal condition still needs to be elucidated. The present study was designed to investigate the effects modulating...

["Immunology","Translational Medicine"]
doi:10.7717/peerj.5638
15 downloads
77 views

Müller glia in the zebrafish retina respond to retinal damage by re-entering the cell cycle, which generates large numbers of retinal progenitors that ultimately replace the lost neurons. In this study we compared the regenerative outcomes of adult zebrafish exposed...

["Cell Biology","Developmental Biology","Molecular Biology","Neuroscience","Ophthalmology"]
doi:10.7717/peerj.5646
19 downloads
91 views

Introduction The present study investigated the crucial role of inflammation-based prognostic scores in locally advanced cervical esophageal squamous cell carcinoma (ESCC) patients who underwent curative concurrent chemoradiotherapy (CCRT). Methods There were 411...

["Gastroenterology and Hepatology","Oncology"]
doi:10.7717/peerj.5655
36 downloads
143 views

Cervical cancer is the fourth most common cancer in women worldwide with human papillomavirus (HPV) being the main cause the disease. Chromosomal amplifications have been identified as a source of upregulation for cervical cancer driver genes but cannot fully explain...

["Computational Biology","Microbiology","Oncology"]
doi:10.7717/peerj.5590
24 downloads
113 views

Dysfunction of the N-methyl-d-aspartate receptor (NMDAR) is thought to play a role in the pathophysiology of neurodevelopmental diseases like schizophrenia. To study the effects of NMDAR dysfunction on synaptic transmission and network oscillations, we used hippocampal...

["Bioengineering","Neuroscience","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.5543
21 downloads
368 views

Individuals with Attention-Deficit Hyperactivity Disorder (ADHD) are often characterized by deficits in working memory (WM), which manifest in academic, professional, and mental health difficulties. To better understand the underlying mechanisms of these presumed...

["Neuroscience","Cognitive Disorders","Psychiatry and Psychology"]
doi:10.7717/peerj.5601
49 downloads
163 views

Purpose Most studies on neuroblastoma (NB) have been conducted in Western countries or Japan. The objective of our study was to analyze clinical and pathological features, MYCN status, surgical methods, and prognosis in Chinese NB patients. Methods A retrospective,...

["Oncology","Pediatrics","Surgery and Surgical Specialties"]
doi:10.7717/peerj.5665
22 downloads
315 views

Background Schizotypy is a set of personality traits that resemble the signs and symptoms of schizophrenia in the general population, and it is associated with various subclinical mental health problems, including sleep disturbances. Additionally, dimensions of...

["Cognitive Disorders","Global Health","Psychiatry and Psychology"]
doi:10.7717/peerj.5615
26 downloads
190 views

Objectives The five-year survival rate of head and neck cancer (HNC) after radiotherapy (RT) varies widely from 35% to 89%. Many studies have addressed the effect of socioeconomic status and urban dwelling on the survival of HNC, but a limited number of studies...

["Dentistry","Oncology","Otorhinolaryngology","Public Health"]
doi:10.7717/peerj.5591
20 downloads
123 views

Combination Index (CI) analysis suggested that MBIC and doxorubicin synergistically inhibited up to 97% of cell proliferation in ER+/PR+MCF-7 and triple negative MDA-MB-231 breast cancer cell lines. Moreover, treatment of the breast cancer cells with the combined...

["Cell Biology","Oncology"]
doi:10.7717/peerj.5577
19 downloads
160 views

Background High myopia is a common ocular disease worldwide. To expand our current understanding of the genetic basis of high myopia, we carried out a whole exome sequencing (WES) study to identify potential causal gene mutations. Methods A total of 20 individuals...

["Bioinformatics","Computational Biology","Genetics","Genomics","Translational Medicine"]
doi:10.7717/peerj.5552
21 downloads
469 views

Background Silver nanoparticles (AgNPs) have been widely used in many commercial products due to their excellent antibacterial ability. The AgNPs are released into the environment, gradually accumulate in the ocean, and may affect animals at high trophic levels,...

["Toxicology","Veterinary Medicine","Immunology","Ecotoxicology","Environmental Contamination and Remediation"]
doi:10.7717/peerj.5432
44 downloads
194 views

Background The leading cause of surface water impairment in United States’ rivers and streams is pathogen contamination. Although use of fecal indicators has reduced human health risk, current approaches to identify and reduce exposure can be improved. One important...

["Microbiology","Public Health","Computational Science","Data Mining and Machine Learning","Spatial and Geographic Information Science"]
doi:10.7717/peerj.5610
39 downloads
117 views

Background Urothelial carcinoma (UC) is the fifth most common malignancy that accounts for 5% of all cancers. Diagnostic markers that predict UC progressions are inadequate. NF-κB contributes towards disease progression upon constitutive activation in many solid...

["Bioinformatics","Pathology","Urology"]
doi:10.7717/peerj.5563

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