Peer-reviewed Articles - Medicine

Purpose Myopia (short-sightedness) is the commonest visual disorder and greatest risk factor for sight threatening secondary pathologies. Myopia and hyperopia can be induced in animal models by rearing with optical lens defocus of opposite sign. The degree of refractive...

["Neuroscience","Ophthalmology"]
doi:10.7717/peerj.6277

Objective In evidence synthesis practice, dealing with binary rare adverse events (AEs) is a challenging problem. The pooled estimates for rare AEs through traditional inverse variance (IV), Mantel-Haenszel (MH), and Yusuf-Peto (Peto) methods are suboptimal, as...

["Clinical Trials","Epidemiology","Evidence Based Medicine","Statistics"]
doi:10.7717/peerj.6295

Background Visualization and calculation of the airway dimensions are important because an increase of airway resistance may lead to life-threatening emergencies. The visualization and calculation of the airway are possible using radiography technique with their...

["Dentistry","Radiology and Medical Imaging"]
doi:10.7717/peerj.6319

Background Hypocalcemia is a common complication of thyroidectomy resulting from an injury to the parathyroid gland. Methylene blue, which is a medication and dye that has been used for more than a century, is safe and readily available. The previous study has...

["Clinical Trials","Epidemiology","Otorhinolaryngology","Surgery and Surgical Specialties"]
doi:10.7717/peerj.6376

Infectious disease dynamics are affected by human mobility more powerfully than previously thought, and thus reliable traceability data are essential. In rural riverine settings, lack of infrastructure and dense tree coverage deter the implementation of cutting-edge...

["Infectious Diseases","Spatial and Geographic Information Science"]
doi:10.7717/peerj.6298
8 downloads
61 views

This study provides information on biological (gonadosomatic index), commercial quality (condition index and meat yield) and biochemical aspects (proximate composition, fatty acids) of the soft tissues of Flexopecten glaber reared in suspended cages in the Ionian...

["Aquaculture, Fisheries and Fish Science","Biochemistry","Food Science and Technology","Marine Biology","Nutrition"]
doi:10.7717/peerj.5810
10 downloads
49 views

Background Monopolar spindle 1 (Mps1/TTK) is an apical dual-specificity protein kinase in the spindle assembly checkpoint (SAC) that guarantees accurate segregation of chromosomes during mitosis. High levels of Mps1 are found in various types of human malignancies,...

["Computational Biology","Oncology"]
doi:10.7717/peerj.6299
20 downloads
171 views

Background Scarlet fever is recognized as being a major public health issue owing to its increase in notifications in mainland China, and an advanced response based on forecasting techniques is being adopted to tackle this. Here, we construct a new hybrid method...

["Mathematical Biology","Epidemiology","Health Policy","Infectious Diseases","Public Health"]
doi:10.7717/peerj.6165
24 downloads
160 views

Background Patients with atrial fibrillation-flutter (AF) admitted on the weekends were initially reported to have poor outcomes. The primary purpose of this study is to re-evaluate the outcomes for weekend versus weekday AF hospitalization using the 2014 Nationwide...

["Cardiology","Global Health","Health Policy"]
doi:10.7717/peerj.6211
40 downloads
143 views

Purpose The most common virus vector used in gene therapy research for ophthalmologic diseases is the adeno-associated virus (AAV) vector, which has been used successfully in a number of preclinical and clinical studies. It is important to evaluate novel AAV vectors...

["Virology","Ophthalmology"]
doi:10.7717/peerj.6317
30 downloads
150 views

The fight against cancer has been a never-ending battle. Limitations of conventional therapies include lack of selectivity, poor penetration and highly toxic to the host. Using genetically modified bacteria as a tumour therapy agent has gained the interest of scientist...

["Bioengineering","Biotechnology","Microbiology","Molecular Biology","Oncology"]
doi:10.7717/peerj.5989
122 downloads
846 views

The recent ‘replication crisis’ in psychology has focused attention on ways of increasing methodological rigor within the behavioral sciences. Part of this work has involved promoting ‘Registered Reports’, wherein journals peer review papers prior to data collection...

["Psychiatry and Psychology","Statistics"]
doi:10.7717/peerj.6232
35 downloads
120 views

Background Prior to the 2017 table tennis season, each participant performed the anterior, posteromedial, and posterolateral the star excursion balance test (SEBT) reach distances in a randomized order. The aim of this study was to assess the effects of table tennis...

["Bioengineering","Kinesiology"]
doi:10.7717/peerj.6262
26 downloads
128 views

In Vietnam, vaccination has played a crucial role in the national strategy for the prevention and control of H5 highly pathogenic avian influenza (HPAI). This study aimed to evaluate antibody responses of immunologically naïve domestic ducks to H5N1 avian influenza...

["Veterinary Medicine","Immunology"]
doi:10.7717/peerj.6268
19 downloads
76 views

Wiskott-Aldrich syndrome (WAS) is a recessive X-linked inmmunodeficiency caused by loss-of-function mutations in the gene encoding the WAS protein (WASp). WASp plays an important role in the polymerization of the actin cytoskeleton in hematopoietic cells through...

["Molecular Biology","Hematology"]
doi:10.7717/peerj.6284

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