Peer-reviewed Articles - Biology

47 downloads
468 views

Sensitivity of short read DNA-sequencing for gene fusion detection is improving, but is hampered by the significant amount of noise composed of uninteresting or false positive hits in the data. In this paper we describe a tiered prioritisation approach to extract...

["Bioinformatics","Genomics","Oncology","Translational Medicine"]
doi:10.7717/peerj.3166
84 downloads
388 views

The Clustered Regularly Interspaced Short Palindromic Repeats associated (CRISPR-Cas) systems consist of RNA-protein complexes that provide bacteria and archaea with sequence-specific immunity against bacteriophages, plasmids, and other mobile genetic elements....

["Biochemistry","Bioinformatics","Evolutionary Studies","Microbiology"]
doi:10.7717/peerj.3161
107 downloads
658 views

Background Conserving biodiversity in tropical landscapes is a major challenge to scientists and conservationists. Current rates of deforestation, fragmentation, and land use intensification are producing variegated landscapes with undetermined values for the conservation...

["Agricultural Science","Biodiversity","Conservation Biology","Ecology","Entomology"]
doi:10.7717/peerj.3125
72 downloads
387 views

The olfaction system of insects plays an important role in mediating various physiological behaviors, including locating hosts, avoiding predators, and recognizing mates and oviposition sites. Therefore, some key genes in the system present valuable opportunities...

["Entomology","Genomics","Molecular Biology"]
doi:10.7717/peerj.3157
1 citation
50 downloads
293 views

Background ABO blood group is a hereditary factor of plasma levels of coagulation factor VIII (FVIII) and von Willebrand factor (VWF). Age and gender have been shown to influence FVIII, VWF, fibrinogen (Fbg), and ADAMTS13 (A disintegrin and metalloprotease with...

["Biochemistry","Global Health","Hematology","Translational Medicine"]
doi:10.7717/peerj.3156
46 downloads
376 views

The filamentous fungus Rhizopus delemar naturally accumulates relatively high amounts of fumarate. Although the culture conditions that increase fumarate yields are well established, the network underlying the accumulation of fumarate is not yet fully understood....

["Biochemistry","Bioinformatics","Biotechnology","Microbiology"]
doi:10.7717/peerj.3133
48 downloads
280 views

Background The endocrinology of skeletal muscle is highly complex and many issues about hormone action in skeletal muscle are still unresolved. Aim of the work is to improve our knowledge on the relationship between skeletal muscle and 17β-estradiol. Methods The...

["Cell Biology","Molecular Biology","Veterinary Medicine"]
doi:10.7717/peerj.3124
145 downloads
578 views

Mediterranean biomes are biodiversity hotspots, and vineyards are important components of the Mediterranean landscape. Over the last few decades, the amount of land occupied by vineyards has augmented rapidly, thereby increasing threats to Mediterranean ecosystems....

["Agricultural Science","Biodiversity","Ecology","Coupled Natural and Human Systems"]
doi:10.7717/peerj.3098
139 downloads
885 views

Aims Mountain ranges in the tropics are characterised by high levels of localised endemism, often-aberrant evolutionary trajectories, and some of the world’s most diverse regional biotas. Here we investigate the evolution of montane endemism, ecology and body size...

["Biodiversity","Biogeography","Taxonomy"]
doi:10.7717/peerj.3077
86 downloads
375 views

Willow is a widely used dioecious woody plant of Salicaceae family in China. Due to their high biomass yields, willows are promising sources for bioenergy crops. In this study, we assembled the complete mitochondrial (mt) genome sequence of S. suchowensis with...

["Bioinformatics","Genomics","Plant Science"]
doi:10.7717/peerj.3148
41 downloads
304 views

Background Meningiomas are common intracranial tumors in humans that frequently recur despite having a predominantly benign nature. Even though these tumors have been shown to commonly express EGFR/c-erbB1 (epidermal growth factor receptor), results from previous...

["Oncology","Pathology","Histology"]
doi:10.7717/peerj.3140
56 downloads
478 views

Gene regulation modulates RNA expression via transcription factors. Post-transcriptional gene regulation in turn influences the amount of protein product through, for example, microRNAs (miRNAs). Experimental establishment of miRNAs and their effects is complicated...

["Bioinformatics","Computational Biology","Computational Science"]
doi:10.7717/peerj.3131
70 downloads
861 views

Background Kettlebell lifting has gained increased popularity as both a form of resistance training and as a sport, despite the paucity of literature validating its use as a training tool. Kettlebell sport requires participants to complete the kettlebell snatch...

["Bioengineering","Anatomy and Physiology","Kinesiology","Orthopedics"]
doi:10.7717/peerj.3111
55 downloads
312 views

The number of protein structures in the PDB database has been increasing more than 15-fold since 1999. The creation of computational models predicting enzymatic function is of major importance since such models provide the means to better understand the behavior...

["Bioinformatics","Computational Biology","Genomics","Computational Science"]
doi:10.7717/peerj.3095
54 downloads
393 views

Background Daily rhythmicity has been observed for a number of hormonal and behavioral variables in mammals. It can be entrained by several external factors, such as light-dark cycle and scheduled feeding. In dromedary camels, daily rhythmicity has been documented...

["Animal Behavior","Veterinary Medicine"]
doi:10.7717/peerj.3074

Top subject areas - Articles

Top subject areas - People

View all subject areas