Peer-reviewed Articles - Biology

59 downloads
346 views

Patterns of habitat selection are influenced by local productivity, resource availability, and predation risk. Species have taken millions of years to hone the macro- and micro-habitats they occupy, but these may now overlap with contemporary human threats within...

["Conservation Biology","Ecology"]
doi:10.7717/peerj.4617
47 downloads
214 views

Well-controlled development leads to uniform body size and a better growth rate; therefore, the ability to determine the growth rate of frogs and their period of sexual maturity is essential for producing healthy, high-quality descendant frogs. To establish a working...

["Agricultural Science","Aquaculture","Fisheries and Fish Science","Zoology"]
doi:10.7717/peerj.4587
77 downloads
290 views

Background Breast cancer stem cells (BCSCs) are associated with the invasion of breast cancer. In recent years, studies have demonstrated different phenotypes among BCSCs. Furthermore, BCSCs of diverse phenotypes are present at different tumour sites and different...

["Cell Biology","Oncology"]
doi:10.7717/peerj.4805
57 downloads
284 views

The blood–brain barrier (BBB), an interface between the systemic circulation and the nervous system, can be a target of cytokines in inflammatory conditions. Pro-inflammatory cytokines tumor necrosis factor-α (TNF-α) and interleukin-1β (IL-1β) induce damage in...

["Cell Biology","Neuroscience","Pharmacology"]
doi:10.7717/peerj.4774
50 downloads
277 views

Elucidating the molecular mechanism of helix–coil transitions of short peptides is a long-standing conundrum in physical chemistry. Although the helix–coil transitions of poly-glutamic acid (PGA) have been extensively studied, the molecular details of its unfolding...

["Biophysics","Computational Biology"]
doi:10.7717/peerj.4769
109 downloads
1,075 views

It has been suggested that a transition between a pelycosaurian-grade synapsid dominated fauna of the Cisuralian (early Permian) and the therapsid dominated fauna of the Guadalupian (middle Permian) was accompanied by, and possibly driven by, a mass extinction...

["Evolutionary Studies","Paleontology"]
doi:10.7717/peerj.4767
46 downloads
349 views

Epichloë endophytes associated with cool-season grass species can protect their hosts from herbivory and can suppress mycorrhizal colonization of the hosts’ roots. However, little is known about whether or not Epichloë endophyte infection can also change the foliar...

["Agricultural Science","Mycology"]
doi:10.7717/peerj.4660
43 downloads
234 views

Proteins that modify the activity of transcription factors (TFs) are often called modulators and play a vital role in gene transcriptional regulation. Alternative splicing is a critical step of gene processing, and differentially spliced isoforms may have different...

["Bioengineering","Bioinformatics","Biotechnology","Genetics","Computational Science"]
doi:10.7717/peerj.4686
53 downloads
491 views

Among copepods, which are the most abundant animals on Earth, the genus Oithona is described as one of the most numerous and plays a major role in the marine food chain and biogeochemical cycles, particularly through the excretion of chitin-coated fecal pellets....

["Marine Biology","Aquatic and Marine Chemistry","Biogeochemistry"]
doi:10.7717/peerj.4685
114 downloads
1,070 views

Outbreaks of coral diseases continue to reduce global coral populations. In the Caribbean, yellow band is a severe and wide-spread disease that commonly affects corals of the Orbicella spp. complex, significantly impeding coral reproduction, and hindering the natural...

["Marine Biology","Zoology","Epidemiology"]
doi:10.7717/peerj.4800
58 downloads
279 views

Malaria is a disease that affects millions of people annually. An intracellular habitat and lack of protein synthesizing machinery in erythrocytes pose numerous difficulties for survival of the human pathogen Plasmodium falciparum. The parasite refurbishes the...

["Cell Biology","Microbiology","Parasitology"]
doi:10.7717/peerj.4757
93 downloads
343 views

Background Alzheimer’ disease (AD) is an ultimately fatal degenerative brain disorder that has an increasingly large burden on health and social care systems. There are only five drugs for AD on the market, and no new effective medicines have been discovered for...

["Bioinformatics","Computational Biology","Cognitive Disorders"]
doi:10.7717/peerj.4756
46 downloads
195 views

In many cases, the DNA-binding activity of a transcription factor does not change, while its transcriptional activity is greatly influenced by the make-up of bound proteins. In this study, we assessed the protein composition and DNA-binding ability of the E2F transcription...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.4755
77 downloads
445 views

Background Tibial stress fracture (TSF) is a common injury in basketball players. This condition has been associated with high tibial shock and impact loading, which can be affected by running speed, footwear condition, and footstrike pattern. However, these relationships...

["Bioengineering","Kinesiology"]
doi:10.7717/peerj.4753
63 downloads
239 views

The varying topography and environment that resulted from paleoorogeny and climate fluctuations of the Himalaya–Hengduan Mountains (HHM) areas had a considerable impact on the evolution of biota during the Quaternary. To understand the phylogeographic pattern and...

["Biodiversity","Biogeography","Genomics","Molecular Biology","Plant Science"]
doi:10.7717/peerj.4748

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