Peer-reviewed Articles - Biology

28 downloads
168 views

Background The kidney is always subjected to high metabolic demand. The aim of this study was to characterize metabolic profiles of a rat model of chronic kidney disease (CKD) with cardiorenal syndrome (CRS) induced by prolonged hypertension. Methods We used inbred...

["Molecular Biology","Cardiology","Nephrology"]
doi:10.7717/peerj.3352
12 downloads
153 views

Biomarkers are the measurable changes associated with a physiological or pathophysiological process. The content of urine frequently changes because it is not controlled by homeostatic mechanisms, and these alterations can be a source of biomarkers. However, urine...

["Biochemistry","Molecular Biology"]
doi:10.7717/peerj.3350
32 downloads
445 views

Coral reef restoration and management techniques are in ever-increasing demand due to the global decline of coral reefs in the last several decades. Coral relocation has been established as an appropriate restoration technique in select cases, particularly where...

["Conservation Biology","Ecology","Marine Biology"]
doi:10.7717/peerj.3346
13 downloads
138 views

Identifying the pathways that control a cellular phenotype is the first step to building a mechanistic model. Recent examples in developmental biology, cancer genomics, and neurological disease have demonstrated how changes in the variability of gene expression...

["Bioinformatics","Cell Biology","Statistics"]
doi:10.7717/peerj.3334
30 downloads
95 views

Microbial transformation can strengthen the antioxidant and antitumor activities of polyphenols. Polyphenols contents, antioxidant and antitumor activities of pine polyphenols and its biotransformation extracts by Aspergillus niger, Aspergillus oryzae, Aspergillus...

["Agricultural Science","Food Science and Technology","Microbiology"]
doi:10.7717/peerj.3264
27 downloads
247 views

Background Freezing is commonly used for food preservation. It is usually done under constant atmospheric pressure (isobaric). While extending the life of the produce, isobaric freezing has detrimental effects. It causes loss of food weight and changes in food...

["Agricultural Science","Biophysics","Cell Biology","Food Science and Technology","Plant Science"]
doi:10.7717/peerj.3322
85 downloads
535 views

Background Fast, accurate and high-throughput identification of bacterial isolates is in great demand. The present work was conducted to investigate the possibility of identifying isolates from unassembled next-generation sequencing reads using custom-made guide...

["Bioinformatics","Computational Biology","Microbiology"]
doi:10.7717/peerj.3353
66 downloads
327 views

The insect exoskeleton is a multifunctional coat with a continuum of mechanical and structural properties constituting the barrier between electromagnetic waves and the internal body parts. This paper examines the ability of beetle exoskeleton to regulate internal...

["Entomology","Zoology"]
doi:10.7717/peerj.3349
42 downloads
266 views

Aim Atorvastatin is a HMG-CoA reductase inhibitor used for hyperlipidemia. Atorvastatin is generally safe but may induce cholestasis. The present study aimed to examine the effects of atorvastatin on hepatic gene expression related to bile acid metabolism and homeostasis,...

["Toxicology","Pharmacology"]
doi:10.7717/peerj.3348
35 downloads
180 views

Characteristics of late maturity in fruit are good agronomic traits for extending the harvest period and marketing time. However, underlying molecular basis of the late-maturing mechanism in fruit is largely unknown. In this study, RNA sequencing (RNA-Seq) technology...

["Agricultural Science","Biotechnology","Molecular Biology","Plant Science"]
doi:10.7717/peerj.3343
32 downloads
203 views

The dynamics and conformational landscape of proteins in organic solvents are events of potential interest in nonaqueous process catalysis. Conformational changes, folding transitions, and stability often correspond to structural rearrangements that alter contacts...

["Bioinformatics","Computational Biology"]
doi:10.7717/peerj.3341
33 downloads
149 views

Background The NDUFS4 gene encodes an 18-kD subunit of mitochondria complex I, and mutations in this gene lead to the development of a severe neurodegenerative disease called Leigh syndrome (LS) in humans. To investigate the disease phenotypes and molecular mechanisms...

["Developmental Biology","Molecular Biology"]
doi:10.7717/peerj.3339
113 downloads
516 views

Topographically complex regions often contain the close juxtaposition of closely related species along elevational gradients. The evolutionary causes of these elevational replacements, and thus the origin and maintenance of a large portion of species diversity...

["Biodiversity","Biogeography","Zoology"]
doi:10.7717/peerj.3335
52 downloads
361 views

Background Network analysis has become a relevant approach to analyze cascading species extinctions resulting from perturbations on mutualistic interactions as a result of environmental change. In this context, it is essential to be able to point out key species,...

["Ecology","Ecosystem Science","Statistics"]
doi:10.7717/peerj.3321
27 downloads
152 views

We investigated intra- and inter-colony sequence variation in a population of the dominant Hawaiian coral Montipora capitata by analyzing marker gene and genomic data. Ribosomal ITS1 regions showed evidence of a reticulate history among the colonies, suggesting...

["Ecology","Evolutionary Studies","Marine Biology"]
doi:10.7717/peerj.3319

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