Peer-reviewed Articles - Biology

41 downloads
219 views

Drug repositioning (i.e., drug repurposing) is the process of discovering new uses for marketed drugs. Historically, such discoveries were serendipitous. However, the rapid growth in electronic clinical data and text mining tools makes it feasible to systematically...

["Bioinformatics","Clinical Trials","Drugs and Devices","Oncology","Statistics"]
doi:10.7717/peerj.3154
16 downloads
131 views

The wood-feeding cockroach Cryptocercus punctulatus Scudder (Blattodea: Cryptocercidae) is an important member of the dead wood (saproxylic) community in montane forests of the southeastern United States. However, its population biology remains poorly understood....

["Entomology","Genetics","Zoology"]
doi:10.7717/peerj.3127
21 downloads
434 views

In a series of experiments, seeds from a temperate seagrass species, Zostera nigricaulis collected in Port Phillip Bay, Victoria, Australia were exposed to a range of salinities (20 PSU pulse/no pulse, 25 PSU, 30 PSU, 35 PSU), temperatures (13 °C, 17 °C, 22 °C),...

["Marine Biology","Plant Science"]
doi:10.7717/peerj.3114
20 downloads
146 views

The spotted wing Drosophila, Drosophila suzukii, is a new pest in Europe and America which causes severe damages, mostly to stone fruit crops. Temperature and humidity are among the most important abiotic factors governing insect development and fitness. In many...

["Ecology","Entomology","Environmental Sciences"]
doi:10.7717/peerj.3112
28 downloads
139 views

Eutrophic aquatic habitats are characterized by the proliferation of vegetation leading to a large standing biomass that upon decomposition may create hypoxic (low-oxygen) conditions. This is indeed the case in nutrient impacted estuaries of Prince Edward Island,...

["Animal Behaviour","Ecology","Environmental Sciences","Marine Biology"]
doi:10.7717/peerj.3080
42 downloads
234 views

Rare hybridisations between deeply divergent animal species have been reported for decades in a wide range of taxa, but have often remained unexplained, mainly considered chance events and reported as anecdotal. Here, we combine field observations with long-term...

["Ecology","Evolutionary Studies","Zoology"]
doi:10.7717/peerj.3072
80 downloads
362 views

Background The present-day amphibian and reptile fauna of Western Siberia are the least diverse of the Palaearctic Realm, as a consequence of the unfavourable climatic conditions that predominate in this region. The origin and emergence of these herpetofaunal groups...

["Biodiversity","Biogeography","Paleontology","Taxonomy","Zoology"]
doi:10.7717/peerj.3025
20 downloads
182 views

Increases in ocean temperature due to climate change are predicted to change the behaviors of marine invertebrates. Altered behaviors of keystone ecosystem engineers such as echinoderms will have consequences for the fitness of individuals, which are expected to...

["Animal Behavior","Ecology","Marine Biology"]
doi:10.7717/peerj.3122
20 downloads
249 views

Objective The purpose of this study was to assess the effects of age, body condition score (BCS) and muscle condition score (MCS) on indirect radial and coccygeal Doppler systolic arterial blood pressure (SAP) measurements in dogs. Methods Sixty-two privately-owned...

["Veterinary Medicine","Internal Medicine"]
doi:10.7717/peerj.3101
79 downloads
290 views

This study explores how curvature in the quokka femur may help to reduce bending strain during locomotion. The quokka is a small wallaby, but the curvature of the femur and the muscles active during stance phase are similar to most quadrupedal mammals. Our hypothesis...

["Computational Biology","Evolutionary Studies","Zoology"]
doi:10.7717/peerj.3100
63 downloads
430 views

DNA metabarcoding, the PCR-based profiling of natural communities, is becoming the method of choice for biodiversity monitoring because it circumvents some of the limitations inherent to traditional ecological surveys. However, potential sources of bias that can...

["Ecology","Molecular Biology"]
doi:10.7717/peerj.3006
31 downloads
213 views

Apoptosis of lymphocytes is associated with immunosuppression and poor prognosis in sepsis. Our previous report showed that histones, nuclear proteins released from damaged or dying cells in sepsis, can mediate lymphocyte apoptosis via mitochondria damage. Grape...

["Cell Biology","Immunology","Pharmacology"]
doi:10.7717/peerj.3108
134 downloads
846 views

The patella is a sesamoid bone located in the major extensor tendon of the knee joint, in the hindlimb of many tetrapods. Although numerous aspects of knee morphology are ancient and conserved among most tetrapods, the evolutionary occurrence of an ossified patella...

["Evolutionary Studies","Palaeontology","Zoology","Anatomy and Physiology"]
doi:10.7717/peerj.3103
18 downloads
196 views

Insect herbivores help maintain forest diversity through selective predation on seedlings of vulnerable tree species. Although the role of natural enemies has been well-studied in tropical systems, relatively few studies have experimentally manipulated insect abundance...

["Ecology","Entomology","Plant Science"]
doi:10.7717/peerj.3102
36 downloads
258 views

Background Cartilage tissue engineering is a fast-evolving field of biomedical engineering, in which the chondrocytes represent the most commonly used cell type. Since research in tissue engineering always consumes a lot of cells, simple and cheap isolation methods...

["Bioengineering","Cell Biology","Orthopedics"]
doi:10.7717/peerj.3079

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