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2025
BX517, an inhibitor of the mammalian phospholipid-dependent kinase 1 (PDK1), antagonizes sucrose-induced plant growth and represses the target of rapamycin (TOR) signaling and the cell cycle through WEE1 kinase in Arabidopsis thaliana
Journal of Plant Physiology
2024
Preclinical evaluation of avutometinib and defactinib in high‐grade endometrioid endometrial cancer
Cancer Medicine
2023
A Novel PDK1/MEK Dual Inhibitor Induces Cytoprotective Autophagy via the PDK1/Akt Signaling Pathway in Non-Small Cell Lung Cancer
Pharmaceuticals
2022
The overview of Mitogen-activated extracellular signal-regulated kinase (MEK)-based dual inhibitor in the treatment of cancers
Bioorganic & Medicinal Chemistry