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2025
Innovative modeling: a diet-induced quail model for progressive pathological changes in uric acid metabolism disorders
Frontiers in Nutrition
2025
Real-time fluorescent and microscopic uricase assay by monitoring the clearance of acridine orange-doped monosodium urate crystals under physiological conditions
Journal of Pharmaceutical and Biomedical Analysis
2024
Signaling pathways in uric acid homeostasis and gout: From pathogenesis to therapeutic interventions
International Immunopharmacology
2024
CRISPR/Cas9 Mediated Deletion of the Uox Gene Generates a Mouse Model of Hyperuricemia with Multiple Complications
Journal of Cardiovascular Translational Research
2023
Dieting alleviates hyperuricemia and organ injuries in uricase-deficient rats via down-regulating cell cycle pathway
PeerJ
2023
The Gouty Kidney: A Reappraisal
Gout, Urate, and Crystal Deposition Disease
2023
Research Progress of Animal Models of Gouty Arthritis
Pharmacy Information
2022
Uricase-Deficient Larval Zebrafish with Elevated Urate Levels Demonstrate Suppressed Acute Inflammatory Response to Monosodium Urate Crystals and Prolonged Crystal Persistence
Genes
2022
Uricase-deficient rats with similarly stable serum uric acid to human’s are sensitive model animals for studying hyperuricemia
PLOS ONE
2022
Comparison of 3 hyperuricemia mouse models and evaluation of food-derived anti-hyperuricemia compound with spontaneous hyperuricemia mouse model
Biochemical and Biophysical Research Communications
2022
Jian Pi Shen Shi formula alleviates hyperuricemia and related renal fibrosis in uricase‐deficient rats via suppression of the collagen‐binding pathway
International Journal of Rheumatic Diseases
2022
Recent Advances in the Production of Genome-Edited Rats
International Journal of Molecular Sciences
2021
Aboriginal Bacterial Flora in the Uricase-Deficient Rat Gut is Not the Main Factor Affecting Serum Uric Acid
Evidence-Based Complementary and Alternative Medicine
2021
Modulation of Urate Transport by Drugs
Pharmaceutics
2021
Uricase deficiency causes mild and multiple organ injuries in rats
PLOS ONE
2020
Rat models of human diseases and related phenotypes: a systematic inventory of the causative genes
Journal of Biomedical Science
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