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2023
Engineered repeat proteins as scaffolds to assemble multi-enzyme systems for efficient cell-free biosynthesis
Nature Communications
2023
The Binding of Different Substrate Molecules at the Docking Site and the Active Site of γ-Secretase Can Trigger Toxic Events in Sporadic and Familial Alzheimer’s Disease
International Journal of Molecular Sciences
2023
Lipid- and substrate-induced conformational and dynamic changes in a glycosyltransferase involved in E. coli LPS synthesis revealed by 19F and 31P NMR
Biochimica et Biophysica Acta (BBA) - Biomembranes
2022
Models of enzyme inhibition and apparent dissociation constants from kinetic analysis to study the differential inhibition of aldose reductase
Journal of Enzyme Inhibition and Medicinal Chemistry
2021
Structural Analysis of the Simultaneous Activation and Inhibition of γ-Secretase Activity in the Development of Drugs for Alzheimer’s Disease
Pharmaceutics
2019
Progress Curve Analysis Within BioCatNet: Comparing Kinetic Models for Enzyme-Catalyzed Self-Ligation
Biotechnology Journal
2018
Comparing enzyme activity modifier equations through the development of global data fitting templates in Excel
PeerJ
2018
Single-molecule theory of enzymatic inhibition
Nature Communications
2017
The Impact of Mathematical Modeling in Understanding the Mechanisms Underlying Neurodegeneration: Evolving Dimensions and Future Directions
CPT: Pharmacometrics & Systems Pharmacology
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