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2025
Targeting Gene C9orf72 Pathogenesis for Amyotrophic Lateral Sclerosis
International Journal of Molecular Sciences
2025
Aggregates associated with amyotrophic lateral sclerosis sequester the actin-binding protein profilin 2
Human Molecular Genetics
2024
A robust evaluation of TDP-43, poly GP, cellular pathology and behavior in an AAV-C9ORF72 (G4C2)66 mouse model
Acta Neuropathologica Communications
2024
Pathogenesis underlying hexanucleotide repeat expansions in C9orf72 gene in amyotrophic lateral sclerosis
Reviews in the Neurosciences
2024
C9ORF72 hexanucleotide repeat expansion: From ALS and FTD to a broader pathogenic role?
Revue Neurologique
2024
ALS’ Perfect Storm: C9orf72-Associated Toxic Dipeptide Repeats as Potential Multipotent Disruptors of Protein Homeostasis
Cells
2023
Assessing Drug Administration Techniques in Zebrafish Models of Neurological Disease
International Journal of Molecular Sciences
2023
Differential response of C9orf72 transcripts following neuronal depolarization
iScience
2023
Handbook of Clinical Neurology
2023
C9ORF72 suppresses JAK-STAT mediated inflammation
iScience
2023
Mitochondrial Dysfunction in Repeat Expansion Diseases
Antioxidants
2023
Handbook of Clinical Neurology
2023
Editorial: Rho family GTPases and their effectors in neuronal survival and neurodegeneration
Frontiers in Cellular Neuroscience
2023
Amyotrophic Lateral Sclerosis Risk Genes and Suppressor
Current Gene Therapy
2022
I-TASSER-MTD: a deep-learning-based platform for multi-domain protein structure and function prediction
Nature Protocols
2022
The progress inC9orf72research: ALS/FTD pathogenesis, functions and structure
Small GTPases
2022
Zebrafish as a model organism for neurodegenerative disease
Frontiers in Molecular Neuroscience
2022
The Interplay Between Autophagy and RNA Homeostasis: Implications for Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Frontiers in Cell and Developmental Biology
2022
Autophagy Dysfunction in ALS: from Transport to Protein Degradation
Journal of Molecular Neuroscience
2022
C9orf72 knockdown alleviates hepatic insulin resistance by promoting lipophagy
Biochemical and Biophysical Research Communications
2021
Role and therapeutic potential of liquid–liquid phase separation in amyotrophic lateral sclerosis
Journal of Molecular Cell Biology
2021
Genes containing hexanucleotide repeats resembling C9ORF72 and expressed in the central nervous system are frequent in the human genome
Neurobiology of Aging
2021
Aberrant Stress Granule Dynamics and Aggrephagy in ALS Pathogenesis
Cells
2021
Cellular and physiological functions of C9ORF72 and implications for ALS/FTD
Journal of Neurochemistry
2021
Leading the way in the nervous system: Lipid Droplets as new players in health and disease
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
2021
Lysosome dysfunction as a cause of neurodegenerative diseases: Lessons from frontotemporal dementia and amyotrophic lateral sclerosis
Neurobiology of Disease
2021
The Role of Nucleocytoplasmic Transport Defects in Amyotrophic Lateral Sclerosis
International Journal of Molecular Sciences
2021
Glial Cell Dysfunction in C9orf72-Related Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Cells
2021
Emerging Evidence Highlighting the Importance of Redox Dysregulation in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS)
Frontiers in Cellular Neuroscience
2021
C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels
Autophagy
2021
Pharmacological Modulators of Small GTPases of Rho Family in Neurodegenerative Diseases
Frontiers in Cellular Neuroscience
2021
C9ORF72 Repeat Expansion Affects the Proteome of Primary Skin Fibroblasts in ALS
International Journal of Molecular Sciences
2020
Genetics of dementia: insights from Latin America
Dementia & Neuropsychologia
2020
Multifaceted Genes in Amyotrophic Lateral Sclerosis-Frontotemporal Dementia
Frontiers in Neuroscience
2020
Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD
Emerging Topics in Life Sciences
2020
Neural Regenerative Nanomedicine
2020
Autophagy as a Potential Therapy for Malignant Glioma
Pharmaceuticals
2020
Clinical Genetics and Genomics of Aging
2020
Drosophila Glia: Models for Human Neurodevelopmental and Neurodegenerative Disorders
International Journal of Molecular Sciences
2020
Structure of the C9orf72 ARF GAP complex that is haploinsufficient in ALS and FTD
Nature
2019
SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis
Autophagy
2019
Mechanisms of Immune Activation by c9orf72-Expansions in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Frontiers in Neuroscience
2019
Prion-Like Propagation of Protein Misfolding and Aggregation in Amyotrophic Lateral Sclerosis
Frontiers in Molecular Neuroscience
2019
Disrupted neuronal trafficking in amyotrophic lateral sclerosis
Acta Neuropathologica
2019
Golgi Fragmentation in Neurodegenerative Diseases: Is There a Common Cause?
Cells
2019
Effect of Mutations in SOD1 and C9orf72 Genes on Autophagy in Lymphomonocytes in Myotrophic Lateral Sclerosis
Bulletin of Experimental Biology and Medicine
2018
Rab-dependent cellular trafficking and amyotrophic lateral sclerosis
Critical Reviews in Biochemistry and Molecular Biology
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