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2025
Beyond Fang's fury: a computational study of the enzyme–membrane interaction and catalytic pathway of the snake venom phospholipase A2 toxin
Chemical Science
2025
Molecular dynamics of Lys49 PLA2-like toxins: Insights into solution and membrane-bound conformations
Toxicon
2025
Major Constituent and Mode of Action of Snake Venom and the Nullifying Activity of Both Synthetic and Herbal Remedies
medtigo Journal of Medicine
2024
Viperidae snake venom phospholipase A2. Biochemical targets in the human blood circulatory system. Review. Part 2
The Scientific Notes of the Pavlov University
2024
Inhibitors and activators for myotoxic phospholipase A2-like toxins from snake venoms – A structural overview
Biochimie
2024
Engineering of pH-dependent antigen binding properties for toxin-targeting IgG1 antibodies using light-chain shuffling
Structure
2024
Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper
Nature Communications
2023
Proteomic profile of the venom of three dark-colored Tityus (Scorpiones: Buthidae) from the tropical rainforests of Costa Rica
Acta Tropica
2023
SDS-induced hexameric oligomerization of myotoxin-II from Bothrops asper assessed by sedimentation velocity and nuclear magnetic resonance
European Biophysics Journal
2023
New Insights into Immunopathology Associated to Bothrops lanceolatus Snake Envenomation: Focus on PLA2 Toxin
International Journal of Molecular Sciences
2023
Cross-reactivity trends when selecting scFv antibodies against snake toxins using a phage display-based cross-panning strategy
Scientific Reports
2023
Discovery of a human monoclonal antibody that cross-neutralizes venom phospholipase A2s from three different snake genera
Toxicon
2023
Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: A comprehensive review
Toxicon
2023
Skeletal muscle fiber hypercontraction induced by Bothrops asper myotoxic phospholipases A2 ex vivo does not involve a direct action on the contractile apparatus
Pflügers Archiv - European Journal of Physiology
2022
Inhibition of enzymatic activities of Bothrops asper snake venom and docking analysis of compounds from plants used in Central America to treat snakebite envenoming
Journal of Ethnopharmacology
2022
In Vivo Neutralization of Myotoxin II, a Phospholipase A2 Homologue from Bothrops asper Venom, Using Peptides Discovered via Phage Display Technology
ACS Omega
2022
Molecular Architecture of the Antiophidic Protein DM64 and its Binding Specificity to Myotoxin II From Bothrops asper Venom
Frontiers in Molecular Biosciences
2022
Venomics of the Scorpion Tityus ocelote (Scorpiones, Buthidae): Understanding Venom Evolution in the Subgenus Archaeotityus
International Journal of Peptide Research and Therapeutics
2022
Anti-HIV Activity of Snake Venom Phospholipase A2s: Updates for New Enzymes and Different Virus Strains
International Journal of Molecular Sciences
2022
Black-necked spitting cobra (Naja nigricollis) phospholipases A2 may cause Trypanosoma brucei death by blocking endocytosis through the flagellar pocket
Scientific Reports
2021
Snake Venom Components: Tools and Cures to Target Cardiovascular Diseases
Molecules
2021
Biogeographical venom variation in the Indian spectacled cobra (Naja naja) underscores the pressing need for pan-India efficacious snakebite therapy
PLOS Neglected Tropical Diseases
2021
Changes in basement membrane components in an experimental model of skeletal muscle degeneration and regeneration induced by snake venom and myotoxic phospholipase A2
Toxicon
2021
The synthetic varespladib molecule is a multi-functional inhibitor for PLA2 and PLA2-like ophidic toxins
Biochimica et Biophysica Acta (BBA) - General Subjects
2021
BthTX-II from Bothrops jararacussu venom has variants with different oligomeric assemblies: An example of snake venom phospholipases A2 versatility
International Journal of Biological Macromolecules
2020
A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A2 on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A2α
Biomolecules
2020
Potent virucidal activity against Flaviviridae of a group IIA phospholipase A2 isolated from the venom of Bothrops asper
Biologicals
2020
12-HETE is a regulator of PGE2 production via COX-2 expression induced by a snake venom group IIA phospholipase A2 in isolated peritoneal macrophages
Chemico-Biological Interactions
2020
Comparative characterization of Viperidae snake venoms from Perú reveals two compositional patterns of phospholipase A2 expression
Toxicon: X
2019
A Secreted Phospholipase A2 Induces Formation of Smooth Muscle Foam Cells Which Transdifferentiate to Macrophage-Like State
Molecules
2019
Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro
Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology
2019
Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: Comparative characterization and synergism between Asp49 and Lys49 variants
Toxicon
2019
Proteomic profiling, functional characterization, and immunoneutralization of the venom of Porthidium porrasi, a pitviper endemic to Costa Rica
Acta Tropica
2019
Neutralizing properties of LY315920 toward snake venom group I and II myotoxic phospholipases A2
Toxicon
2018
Intravascular hemolysis induced by phospholipases A 2 from the venom of the Eastern coral snake, Micrurus fulvius : Functional profiles of hemolytic and non-hemolytic isoforms
Toxicology Letters
2018
Non-neurotoxic activity of Malayan krait (Bungarus candidus) venom from Thailand
Journal of Venomous Animals and Toxins including Tropical Diseases
2018
A novel pentameric phospholipase A2 myotoxin (PophPLA2) from the venom of the pit viper Porthidium ophryomegas
International Journal of Biological Macromolecules
2018
A myotoxic Lys49 phospholipase A2-homologue is the major component of the venom of Bothrops cotiara from Misiones, Argentina
Toxicon
2017
Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles)
Toxicon
2017
Comparative analyses of putative toxin gene homologs from an Old World viper,Daboia russelii
PeerJ
2017
Purification and partial characterization of an anticoagulant PLA2 from the venom of Indian Daboia russelii that induces inflammation through upregulation of proinflammatory mediators
Journal of Biochemical and Molecular Toxicology
2017
Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative “myotoxic cluster”
Biochimie
2016
Divergent functional profiles of acidic and basic phospholipases A2 in the venom of the snake Porthidium lansbergii lansbergii
Toxicon
2016
Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2
Toxicology Letters
2015
Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids
Toxicon
2015
Antitumor potential of the myotoxin BthTX-I from Bothrops jararacussu snake venom: evaluation of cell cycle alterations and death mechanisms induced in tumor cell lines
Journal of Venomous Animals and Toxins including Tropical Diseases
2015
A constant area monolayer method to assess optimal lipid packing for lipolysis tested with several secreted phospholipase A2
Biochimica et Biophysica Acta (BBA) - Biomembranes
2014
Synergism between Basic Asp49 and Lys49 Phospholipase A2 Myotoxins of Viperid Snake Venom In Vitro and In Vivo
PLoS ONE
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