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2025
Novel benzofuran-conjugated indolin-2-ones as anticancer agents; design, synthesis, biological assessments, and molecular modeling insights
Bioorganic Chemistry
2025
Thiazolidinedione Derivatives as Anticancer Agents: Synthetic Strategies, SAR, and Therapeutic Potential
Journal of Heterocyclic Chemistry
2025
Exploring Thiazolidine-2,4‑dione derivatives as privileged scaffolds for targeted anticancer agents: Biological activity and structure-activity relationship (SAR) insights
Journal of Molecular Structure
2025
New phenylpiperazine-thiazolidine-2,4-dione hybrids targeting MAO inhibition: Synthesis, biological evaluation, kinetic study and in silico insights
Bioorganic & Medicinal Chemistry
2025
Synthesis and in vitro cytotoxic evaluation of pyrazolo[1,5-c]quinazoline-triazole conjugates
Journal of Molecular Structure
2024
Role of SGLT2 Inhibitors, DPP-4 Inhibitors, and Metformin in Pancreatic Cancer Prevention
Cancers
2024
3,5-Disubstituted-thiazolidine-2,4-dione hybrids as antidiabetic agents: Design, synthesis, in-vitro and In vivo evaluation
European Journal of Medicinal Chemistry
2024
Indole clubbed 2,4‐thiazolidinedione linked 1,2,3‐triazole as a potent antimalarial and antibacterial agent against drug‐resistant strain and molecular modeling studies
Archiv der Pharmazie
2024
Repurposing metabolic regulators: antidiabetic drugs as anticancer agents
Molecular Biomedicine
2024
Design, Synthesis, Biological Evaluation, and Molecular Docking Studies of N3‐Functionalized TZD‐Indole Conjugates as Potential Anticancer Agents
ChemistrySelect
2023
Peptide Helix-Y12 as Potential Effector for Peroxisome Proliferator-Activated Receptors
PPAR Research
2023
Does NUCB2/Nesfatin-1 Influence Eating Behaviors in Obese Patients with Binge Eating Disorder? Toward a Neurobiological Pathway
Nutrients
2023
Repurposing drugs targeting metabolic diseases for cancer therapeutics
Drug Discovery Today
2023
Rosiglitazone has a null association with the risk of prostate cancer in type 2 diabetes patients
Frontiers in Endocrinology
2022
Current status and future prospects of molecular hybrids with thiazolidinedione (TZD) scaffold in anticancer drug discovery
Journal of Molecular Structure
2022
The anticancer effects of Metformin in the male germ tumor SEM-1 cell line are mediated by HMGA1
Frontiers in Endocrinology
2022
Probing intermolecular interactions and binding stability of kaempferol, quercetin and resveratrol derivatives with PPAR-γ: docking, molecular dynamics and MM/GBSA approach to reveal potent PPAR- γ agonist against cancer
Journal of Biomolecular Structure and Dynamics
2022
A Scoping Review of the Use of Pioglitazone in the Treatment of Temporo-Mandibular Joint Arthritis
International Journal of Environmental Research and Public Health
2022
Design and Synthesis of Echitamine-inspired Hybrid Analogues Containing Thiazolidinediones as Potential Pancreatic Lipase Inhibitors
Letters in Drug Design & Discovery
2022
Anti-Diabetic Potentials of Thiazolidinedione Analogues with Efficient Synthetic Procedures: A Review of Literature
Mini-Reviews in Organic Chemistry
2022
The medicinal perspective of 2,4‐thiazolidinediones based ligands as antimicrobial, antitumor and antidiabetic agents: A review
Archiv der Pharmazie
2022
Design, Molecular Docking, Synthesis, Anticancer and Anti-Hyperglycemic Assessments of Thiazolidine-2,4-diones Bearing Sulfonylthiourea Moieties as Potent VEGFR-2 Inhibitors and PPARγ Agonists
Pharmaceuticals
2021
Cancer and diabetes: the interlinking metabolic pathways and repurposing actions of antidiabetic drugs
Cancer Cell International
2021
Activation of the Peroxisome Proliferator-Activated Receptors (PPAR-α/γ) and the Fatty Acid Metabolizing Enzyme Protein CPT1A by Camel Milk Treatment Counteracts the High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease
PPAR Research
2021
Insulin Resistance and Cancer: In Search for a Causal Link
International Journal of Molecular Sciences
2021
Synthetically-tailored and nature-derived dual COX-2/5-LOX inhibitors: Structural aspects and SAR
European Journal of Medicinal Chemistry
2021
Design, synthesis,in silicomolecular modelling studies and biological evaluation of novel indole-thiazolidinedione hybrid analogues as potential pancreatic lipase inhibitors
New Journal of Chemistry
2020
Bioactive pyrrole-based compounds with target selectivity
European Journal of Medicinal Chemistry
2020
Multi-Targeting Bioactive Compounds Extracted from Essential Oils as Kinase Inhibitors
Molecules
2020
MicroRNA-1281 as a Novel Circulating Biomarker in Patients With Diabetic Retinopathy
Frontiers in Endocrinology
2020
An Insight into the Synthesis and SAR of 2,4-Thiazolidinediones (2,4-TZD) as Multifunctional Scaffold: A Review
Mini-Reviews in Medicinal Chemistry
2020
The role of glycogen synthase kinase 3 beta in multiple sclerosis
Biomedicine & Pharmacotherapy
2020
Design, synthesis, and biological evaluation of imidazopyridine‐linked thiazolidinone as potential anticancer agents
Archiv der Pharmazie
2020
Mediterranean Diet Nutrients to Turn the Tide against Insulin Resistance and Related Diseases
Nutrients
2020
Obesity-related hypoxia via miR-128 decreases insulin-receptor expression in human and mouse adipose tissue promoting systemic insulin resistance
eBioMedicine
2020
The role of diosgenin in diabetes and diabetic complications
The Journal of Steroid Biochemistry and Molecular Biology
2019
Medicinal chemistry of indole derivatives: Current to future therapeutic prospectives
Bioorganic Chemistry
2019
Cell-line characterization by infrared-induced pyroelectric effect
Biosensors and Bioelectronics