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2025
Phase 1 single-centre placebo- and etomidate-controlled study in healthy volunteers to assess safety, tolerability, clinical effects, and pharmacokinetics of intravenous methoxyethyl etomidate hydrochloride (ET-26)
British Journal of Anaesthesia
2025
The pharmacokinetics and Concentration-QTc analysis of a new etomidate analog ET-26-HCl: a phase I trial in healthy Chinese subjects
Frontiers in Pharmacology
2022
E161111 is an ultra-short-acting etomidate analogue with stable haemodynamics that elicits only slight adrenocortical suppression in rats
PeerJ
2021
Propofol differentially induces unconsciousness and respiratory depression through distinct interactions between GABA<sub>A</sub> receptor and GABAergic neuron in corresponding nuclei
Acta Biochimica et Biophysica Sinica
2020
Metabolite identification, tissue distribution, excretion and preclinical pharmacokinetic studies of ET-26-HCl, a new analogue of etomidate
Royal Society Open Science
2020
New insights for screening etomidate analogues in the human H295R cell model
Toxicology in Vitro