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2025	The role of the SIX family in cancer development and therapy: Insights from foundational and cutting-edge research Critical Reviews in Oncology/Hematology Shiyu Huang, Yujie Chen, Min Hu, Shujie Fu, Zhiyuan Yao, Hao He, Lei Wang, Zhiyuan Chen, Xiuheng Liu
2025	Sine oculis homeobox homolog family function in gastrointestinal cancer: Progression and comprehensive analysis World Journal of Clinical Oncology Yang-Zheng Lan, Zheng Wu, Wen-Jia Chen, Xin-Ning Yu, Hua-Tao Wu, Jing Liu
2025	Single-cell and bulk transcriptome sequencing identifies circadian rhythm disruption and cluster-specific clinical insights in colorectal tumorigenesis Discover Oncology Chen Liu, Jingyang Liu, Jing Shao, Xiaoman Zhao, Lin Xie, Mengyao Shang, Ying Li, Weiming Li
2024	miR-540-3p partially recovers the locomotor function of spinal cord injury mice by targeting SIX4/Yap1 and inactivation of astrocytes Neurological Research Yang Wang, Tianlun Zhao, Wei-Chih Chen, Yongsheng Zheng, Weikang Xu, Shuai Huang
2024	Hinokiflavone exerts dual regulation on apoptosis and pyroptosis via the SIX4/Stat3/Akt pathway to alleviate APAP-induced liver injury Life Sciences Yi-Ying Liu, Yang Zhang, Guan-Yue Shan, Jun-Ya Cheng, Hui Wan, Yu-Xin Zhang, Hai-Jun Li
2023	SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression Cancer Research Communications Beiyuan Liang, Evan H. Zhang, Zhen Ye, Hayden Storts, Wei Jin, Xinru Zheng, Hannah Hylton, Olivia Zaleski, Xuanxuan Xing, Wayne Miles, Jing J. Wang
2023	Combination of SIX4-siRNA and temozolomide inhibits the growth and migration of A-172 glioblastoma cancer cells Naunyn-Schmiedeberg's Archives of Pharmacology Zahra Jodari Mohammadpour, Reza Mohammadzadeh, Darya Javadrashid, Amir Baghbanzadeh, Mohammad Amin Doustvandi, Nesa Barpour, Behzad Baradaran
2023	Comprehensive DNA methylation profiling of COVID-19 and hepatocellular carcinoma to identify common pathogenesis and potential therapeutic targets Clinical Epigenetics Huiyan Luo, Jixin Chen, Qiyin Jiang, Yifan Yu, Miaolun Yang, Yuehua Luo, Xiongwen Wang
2023	Knockdown of SIX4 inhibits pancreatic cancer cells via apoptosis induction Medical Oncology Mohammad Heiat, Ehsan Rezaei, Javad Gharechahi, Masoumeh Abbasi, Javad Behroozi, Mohammad Ali Abyazi, Behzad Baradaran
2022	FOXA1 Leads to Aberrant Expression of SIX4 Affecting Cervical Cancer Cell Growth and Chemoresistance Analytical Cellular Pathology Zhuo Wang, Bao-Sheng Sun, Zhi-Shen Chen, Kang-Kang Zhao, Yun-Long Wang, Fan-Xu Meng, Yang Zhang
2022	An Optimized Isotopic Photocleavable Tagging Strategy for Site-Specific and Quantitative Profiling of Protein O-GlcNAcylation in Colorectal Cancer Metastasis ACS Chemical Biology Jialin Liu, Yi Hao, Chunting Wang, Yangya’nan Jin, Yong Yang, Jin Gu, Xing Chen
2022	Silencing of SiX-4 enhances the chemosensitivity of melanoma cells to Cisplatin Pathology - Research and Practice Aysan Fallah vazirabad, Saeed Noorolyai, Elham Baghbani, Soltanali Mahboob, Felor Zargari, Shima rahmani, Amin Sorkhabi, Nooshin montazami, Pouriya Sameti, Behzad Baradaran
2022	The expression changes of transcription factors including ANKZF1, LEF1, CASZ1, and ATOH1 as a predictor of survival rate in colorectal cancer: a large-scale analysis Cancer Cell International Manizheh Sajadi, Mohammad Fazilti, Habibollah Nazem, Mohammad Mahdevar, Kamran Ghaedi
2022	Comprehensive analysis of the potential role and prognostic value of sine oculis homeobox homolog family in colorectal cancer World Journal of Gastrointestinal Oncology Ze-Xuan Fang, Chun-Lan Li, Zheng Wu, Yan-Yu Hou, Hua-Tao Wu, Jing Liu
2021	The SIX Family of Transcription Factors: Common Themes Integrating Developmental and Cancer Biology Frontiers in Cell and Developmental Biology Logan Meurer, Leonard Ferdman, Beau Belcher, Troy Camarata
2021	Upregulation of SIX4 indicates poor clinical outcome and promotes tumor growth and cell metastasis in esophageal squamous cell carcinoma Thoracic Cancer Yanping Li, Xiaomei Jiang, Xiaoyan Yan, Yanzheng Wang
2020	SIX4 promotes hepatocellular carcinoma metastasis through upregulating YAP1 and c-MET Oncogene Qin He, Zhuoying Lin, Zhihui Wang, Wenjie Huang, Dean Tian, Mei Liu, Limin Xia
2020	miR‐802 inhibits the proliferation, invasion, and epithelial‐mesenchymal transition of glioblastoma multiforme cells by directly targeting SIX4 Cell Biochemistry and Function Wu Huang, Yu Shi, Bin Han, Qilong Wang, Bin Zhang, Chunjian Qi, Fang Liu
2020	Identification of Hub Genes Related to Carcinogenesis and Prognosis in Colorectal Cancer Based on Integrated Bioinformatics Mediators of Inflammation Benjiao Gong, Yanlei Kao, Chenglin Zhang, Fudong Sun, Zhaohua Gong, Jian Chen
2020	Prognosis prediction model based on competing endogenous RNAs for recurrence of colon adenocarcinoma BMC Cancer Li Peng Jin, Tao Liu, Fan Qi Meng, Jian Dong Tai
2020	Glycogen Phosphorylase B Is Regulated by miR101-3p and Promotes Hepatocellular Carcinoma Tumorigenesis Frontiers in Cell and Developmental Biology Guangying Cui, Huifen Wang, Wenli Liu, Jiyuan Xing, Wengang Song, Zhaohai Zeng, Liwen Liu, Haiyu Wang, Xuemei Wang, Hong Luo, Xiaoyang Leng, Shen Shen
2020	<p>Gene Expression Signature to Predict Prognosis and Adjuvant Chemosensitivity of Colorectal Cancer Patients</p> Cancer Management and Research Jianxia Li, Jianwei Zhang, Huabin Hu, Yue Cai, Jiayu Ling, Zehua Wu, Yanhong Deng
2020	Effect of lncRNA WT1-AS regulating WT1 on oxidative stress injury and apoptosis of neurons in Alzheimer's disease via inhibition of the miR-375/SIX4 axis Aging Quanbao Wang, Xiumin Ge, Jie Zhang, Licheng Chen
2019	Six2 is negatively correlated with prognosis and facilitates epithelial-mesenchymal transition via TGF-β/Smad signal pathway in hepatocellular carcinoma Hepatobiliary & Pancreatic Diseases International Zheng-Hua Wan, Yun-Han Ma, Tian-Yi Jiang, Yun-Kai Lin, Yuan-Yuan Shi, Ye-Xiong Tan, Li-Wei Dong, Hong-Yang Wang
2019	In silico learning of tumor evolution through mutational time series Proceedings of the National Academy of Sciences Noam Auslander, Yuri I. Wolf, Eugene V. Koonin
2019	PI3K/ Akt/ mTOR Pathway as a Therapeutic Target for Colorectal Cancer: A Review of Preclinical and Clinical Evidence Current Drug Targets Arunaksharan Narayanankutty
2018	Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele Disease Models & Mechanisms Masanori Takahashi, Masaru Tamura, Shigeru Sato, Kiyoshi Kawakami
2018	Suppression of Notch1 and AKT mediated epithelial to mesenchymal transition by Verrucarin J in metastatic colon cancer Cell Death & Disease Deeksha Pal, Ashish Tyagi, Balaji Chandrasekaran, Houda Alattasi, Murali K. Ankem, Arun K. Sharma, Chendil Damodaran
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