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2025
Evaluation of metformin’s effect on the adult and juvenile stages of Schistosoma mansoni: an in-vitro study
Journal of Parasitic Diseases
2025
Regulatory effects of the Tartary buckwheat starch-flavonoid complex on glycometabolism and intestinal flora in type 2 diabetic mice
Food Bioscience
2025
Metformin prevents diabetes development in type 1 diabetes models via suppression of mTOR and STAT3 signaling in immune cells
Scientific Reports
2025
The metformin administration on pancreatic tissue damage in metastatic rat prostate cancer and STZ induced diabetes model
Journal of Molecular Histology
2025
A plasma metabolomic analysis revealed the metabolic regulatory mechanism of the water extract of Dendrobium huoshanense in improving streptozotocin-induced type 1 diabetes model rats
Journal of Natural Medicines
2025
Deglet Noor date derived polysaccharides lower blood glucose levels and modulate the gut microbiota in a streptozotocin-induced type-1 diabetic mouse model
Food & Function
2025
Bioassay-Guided Isolation and Active Compounds Identification of the AntiDiabetic Fractions of Centaurea calcitrapa Extract and the Predicted Interaction Mechanism
Molecules
2025
Antidepressant- and anxiolytic-like effects of linezolid in streptozotocin-induced diabetic mice via modulation of brain serotonin and plasma corticosterone activity
Biochemical and Biophysical Research Communications
2025
Combined Metformin and Baricitinib Therapy Attenuates Inflammation in STZ‐Induced Diabetic Rats via AMPK/JAK–STAT Pathway Crosstalk
Endocrinology, Diabetes & Metabolism
2025
Thymoquinone Mediates Müller Cell Apoptosis via miR-29b/SP1 Pathway: A Potential Therapeutic Approach in Diabetic Retinopathy
Drug Research
2024
Reduction of hyperglycemia in STZ-induced diabetic mice by prophylactic treatment with heat-killed Mycobacterium aurum: possible effects on glucose utilization, mitochondrial uncoupling, and oxidative stress in liver and skeletal muscle
Frontiers in Endocrinology
2024
Alzheimer's disease‐related brain insulin resistance and the prospective therapeutic impact of metformin
Journal of Neuroendocrinology
2024
A comparison of the Anti-diabetic Potential of Magnetized Water, Metformin, and Their Combination in A Rat Model of Type II Diabetes
Biomedical and Pharmacology Journal
2024
The efficacy of using metformin and/or quercetin for amelioration of gamma-irradiation induced tongue toxicity in diabetic rats
BMC Oral Health
2023
Management of spontaneous diabetes mellitus in a companion rat (Rattus norvegicus)
Journal of Exotic Pet Medicine
2023
Silver Nanoparticles Decorated with Curcumin Enhance the Efficacy of Metformin in Diabetic Rats via Suppression of Hepatotoxicity
Toxics
2023
The AMPK activator metformin improves recovery from demyelination by shifting oligodendrocyte bioenergetics and accelerating OPC differentiation
Frontiers in Cellular Neuroscience
2023
Anti-diabetic Effects of Two Species of Eryngium on Streptozotocin-induced Diabetic Mice
Jundishapur Journal of Natural Pharmaceutical Products
2023
Antioxidant, antihyperglycemic, and antihyperlipidemic properties of Chimonanthus salicifolius S. Y. Hu leaves in experimental animals: modulation of thioredoxin and glutathione systems, renal water reabsorption, and gut microbiota
Frontiers in Nutrition
2023
Ghrelin attenuates inflammation in diabetic lung disease by TLR4 pathway in vivo and in vitro
BMJ Open Diabetes Research & Care
2022
Gymnemic acid protects murine pancreatic β‐cells by moderating hyperglycemic stress‐induced inflammation and apoptosis in type 1 diabetic rats
Journal of Biochemical and Molecular Toxicology
2022
Curcumin activates Nrf2/HO‐1 signaling to relieve diabetic cardiomyopathy injury by reducing ROS in vitro and in vivo
The FASEB Journal
2022
1,2,3,4,6‑penta‑O‑galloyl‑β‑D‑glucose alleviates inflammation and oxidative stress in diabetic nephropathy rats through MAPK/NF‑κB and ERK/Nrf2/HO‑1 signaling pathways
Experimental and Therapeutic Medicine
2022
Effect of crude polysaccharide from seaweed, Dictyopteris divaricata (CDDP) on gut microbiota restoration and anti-diabetic activity in streptozotocin (STZ)-induced T1DM mice
Gut Pathogens
2022
Metformin versus silymarin as hepatoprotective agents in mice fibrotic model caused by carbon tetrachloride
Annales Pharmaceutiques Françaises
2021
Allicin, an Antioxidant and Neuroprotective Agent, Ameliorates Cognitive Impairment
Antioxidants
2021
The activity of curcumin combined with ZnCl₂ on streptozotocin-induced diabetic rats. An anti-diabetic, anti-hyperlipidemic study ‎
Journal Of Advanced Pharmacy Education And Research
2021
Piperlongumine attenuates oxidative stress, inflammatory, and apoptosis through modulating the GLUT‐2/4 and AKT signaling pathway in streptozotocin‐induced diabetic rats
Journal of Biochemical and Molecular Toxicology
2021
Schisandrin B ameliorates non‐alcoholic liver disease through anti‐inflammation activation in diabetic mice
Drug Development Research
2021
Metformin improves cognitive impairment in diabetic mice induced by a combination of streptozotocin and isoflurane anesthesia
Bioengineered
2021
Ibrutinib ameliorates cerebral ischemia/reperfusion injury through autophagy activation and PI3K/Akt/mTOR signaling pathway in diabetic mice
Bioengineered
2021
Ononis natrix L. Lowers the Blood Glucose Concentration in Wistar Rats with Streptozotocin-induced Diabetes Mellitus
Endocrine, Metabolic & Immune Disorders - Drug Targets
2021
Metformin attenuated histopathological ocular deteriorations in a streptozotocin-induced hyperglycemic rat model
Naunyn-Schmiedeberg's Archives of Pharmacology
2020
Effects of Early MSC Intervention on Preventing the Streptozotocin-Induced T1DM Progression in Mice
Oxidative Medicine and Cellular Longevity
2020
Antidiabetic drug metformin affects the developmental competence of cleavage-stage embryos
Journal of Assisted Reproduction and Genetics
2020
<p>Ubiquitin-Fold Modifier-1 Participates in the Diabetic Inflammatory Response by Regulating NF-κB p65 Nuclear Translocation and the Ubiquitination and Degradation of IκBα</p>
Drug Design, Development and Therapy
2020
Metformin as a protective agent against natural or chemical toxicities: a comprehensive review on drug repositioning
Journal of Endocrinological Investigation
2020
Identification of an Anti-diabetic, Orally Available Small Molecule that Regulates TXNIP Expression and Glucagon Action
Cell Metabolism
2020
Metformin Had Potential to Increase Endocan Levels in STZ-Induced Diabetic Mice
Pharmaceutical Sciences
2020
Berberine Inhibits Gluconeogenesis in Skeletal Muscles and Adipose Tissues in Streptozotocin-induced Diabetic Rats via LKB1-AMPK-TORC2 Signaling Pathway
Current Medical Science
2020
Date palm fruit extract ameliorated pancreatic apoptosis, endocrine dysfunction and regulatory inflammatory cytokines in Streptozotocin-induced diabetes in rats
Environmental Science and Pollution Research
2020
Metabolic abnormalities exacerbate Sjögren’s syndrome by and is associated with increased the population of interleukin–17–producing cells in NOD/ShiLtJ mice
Journal of Translational Medicine
2019
Hesperidin ameliorates pancreatic β-cell dysfunction and apoptosis in streptozotocin-induced diabetic rat model
Life Sciences
2019
Isolation, characterization, and therapeutic activity of bergenin from marlberry (Ardisia colorata Roxb.) leaf on diabetic testicular complications in Wistar albino rats
Environmental Science and Pollution Research
2019
Allicin and health: A comprehensive review
Trends in Food Science & Technology
2019
Inflammatory Consequences of Maternal Diabetes on the Offspring Brain: a Hippocampal Organotypic Culture Study
Neurotoxicity Research
2018
The potential effect of garlic extract and curcumin nanoparticles against complication accompanied with experimentally induced diabetes in rats
Phytomedicine
2018
Prebiotic Mannan-Oligosaccharides Augment the Hypoglycemic Effects of Metformin in Correlation with Modulating Gut Microbiota
Journal of Agricultural and Food Chemistry
2018
Mechanochemical preparation of kaempferol intermolecular complexes for enhancing the solubility and bioavailability
Drug Development and Industrial Pharmacy
2018
Distinct contributions of hyperglycemia and high-fat feeding in metabolic syndrome-induced neuroinflammation
Journal of Neuroinflammation