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2025
Dendrobium nobile Lindl. alkaloids protect CCl4-induced acute liver injury via upregulating LAMP1 expression and activating autophagy flux
Journal of Natural Medicines
2025
Dendrobium nobile Lindl. alkaloids improve lipid metabolism by increasing LDL uptake through regulation of the LXRα/IDOL/LDLR pathway and inhibition of PCSK9 expression in HepG2 cells
Experimental and Therapeutic Medicine
2024
Dendrobium nobile Lindl ameliorates learning and memory deficits in scopolamine-treated mice
Journal of Ethnopharmacology
2024
A high-quality chromosomal-level reference genome of Dendrobium nobile Lindl. provides new insights into the biosynthesis and accumulation of picrotoxane-type sesquiterpenoid alkaloids
Industrial Crops and Products
2024
Phytochemical Profile of Alkaloid Extract from Dendrobium huoshanense and Inhibitory Effects against Oxidative Stress in H2O2‐Induced PC12 Cells
Chemistry & Biodiversity
2024
Dendrobium nobile Lindl. alkaloid decreases Tau hyperphosphorylation via regulating PI3K/Akt/GSK-3β pathway in vitro and in vivo
Journal of Ethnopharmacology
2024
Protein kinases as therapeutic targets for Alzheimer’s disease: a brief review
Exploration of Neuroprotective Therapy
2024
COP-22 Alleviates d-Galactose–Induced Brain Aging by Attenuating Oxidative Stress, Inflammation, and Apoptosis in Mice
Molecular Neurobiology
2024
Dendrobine Ameliorates Alzheimer’s Disease-like Pathology and Cognitive Decline in 3 × Tg-AD Mice
Brain Sciences
2024
The Chemical Structure and Pharmacological Activity of Sesquiterpenoids in Dendrobium Sw.
Molecules
2023
The protective effects of Dendrobium nobile Lindl. alkaloids (DNLA) against CUMS-induced anxiety/depression and hippocampal transcriptome changes in rats
Pharmacological Research - Modern Chinese Medicine
2023
Research progress of plant‐derived natural alkaloids in central nervous system diseases
Phytotherapy Research
2023
Anti-depressant-like effect of fermented Gastrodia elata Bl. by regulating monoamine levels and BDNF/NMDAR pathways in mice
Journal of Ethnopharmacology
2023
Proteomic analysis of anti-aging effects of Dendrobium nobile Lindl. alkaloids in aging-accelerated SAMP8 mice
Experimental Gerontology
2023
Dendrobium species regulate energy homeostasis in neurodegenerative diseases: a review
Food Science and Human Wellness
2023
Plasma long non-coding RNAs ASMTL-AS1, AP001363.1, AC005730.3 and AL133415.1 as a potential biomarker for Alzheimer’s disease
Neurological Research
2023
The pathomimetic oAβ25–35 model of Alzheimer's disease: Potential for screening of new therapeutic agents
Pharmacology & Therapeutics
2023
Discovery of a 4-Hydroxy-3′-Trifluoromethoxy-Substituted Resveratrol Derivative as an Anti-Aging Agent
Molecules
2023
Natural bioactive compounds in Alzheimer's disease: From the perspective of type 3 diabetes mellitus
Frontiers in Aging Neuroscience
2023
Nanocarriers for the Delivery of Neuroprotective Agents in the Treatment of Ocular Neurodegenerative Diseases
Pharmaceutics
2023
Dendrobine Alleviates Cellular Senescence and Osteoarthritis via the ROS/NF-κB Axis
International Journal of Molecular Sciences
2022
Dendrobium Nobile Lindl. Alkaloid Suppresses NLRP3-Mediated Pyroptosis to Alleviate LPS-Induced Neurotoxicity
Frontiers in Pharmacology
2022
The Cognitive-Enhancing Effects of Dendrobium nobile Lindl Extract in Sleep Deprivation-Induced Amnesic Mice
Frontiers in Psychiatry
2022
Identification of Dendrobiums in situ by Raman spectroscopy and micro-computed tomography imaging
PeerJ Analytical Chemistry
2022
Dendrobium nobile protects retinal cells from UV-induced oxidative stress damage via Nrf2/HO-1 and MAPK pathways
Journal of Ethnopharmacology
2022
Dendrobium nobile Lindl. Alkaloids Ameliorate Aβ25-35-Induced Synaptic Deficits by Targeting Wnt/β-Catenin Pathway in Alzheimer’s Disease Models
Journal of Alzheimer's Disease
2022
Metabolism of Du Zhong Formula in rats using UPLC‐Q‐TOF/MS
Journal of Mass Spectrometry
2022
Medicine-Food Herbs against Alzheimer’s Disease: A Review of Their Traditional Functional Features, Substance Basis, Clinical Practices and Mechanisms of Action
Molecules
2022
Transcriptome Analysis of Protection by Dendrobium nobile Alkaloids (DNLA) against Chronic Alcoholic Liver Injury in Mice
Biomedicines
2022
Alkaloids from Dendrobium and their biosynthetic pathway, biological activity and total synthesis
Phytomedicine
2022
Natural Composition and Biosynthetic Pathways of Alkaloids in Medicinal Dendrobium Species
Frontiers in Plant Science
2022
Research progress in traditional Chinese medicine in the treatment of Alzheimer’s disease and related dementias
Frontiers in Pharmacology
2022
Potential neuroprotection by Dendrobium nobile Lindl alkaloid in Alzheimer’s disease models
Neural Regeneration Research
2021
Prebiotic Lactulose Ameliorates the Cognitive Deficit in Alzheimer’s Disease Mouse Model through Macroautophagy and Chaperone-Mediated Autophagy Pathways
Journal of Agricultural and Food Chemistry
2021
Beneficial effects of Dendrobium nobile Lindl. Alkaloids (DNLA) on anxiety and depression induced by chronic unpredictable stress in rats
Brain Research
2021
RNA-Seq analysis of the protection by Dendrobium nobile alkaloids against carbon tetrachloride hepatotoxicity in mice
Biomedicine & Pharmacotherapy
2021
Identification, Biological Activities and Biosynthetic Pathway of Dendrobium Alkaloids
Frontiers in Pharmacology
2021
Dendrobine Inhibits γ-Irradiation-Induced Cancer Cell Migration, Invasion and Metastasis in Non-Small Cell Lung Cancer Cells
Biomedicines
2021
Protective Effects and Mechanisms of Dendrobium nobile Lindl. Alkaloids on PC12 Cell Damage Induced by Aβ25-35
Behavioural Neurology
2020
Dendrobium nobile Lindl alkaloid and metformin ameliorate cognitive dysfunction in senescence-accelerated mice via suppression of endoplasmic reticulum stress
Brain Research
2020
Dendrobium nobile Lindl. Alkaloids Ameliorate Cognitive Dysfunction in Senescence Accelerated SAMP8 Mice by Decreasing Amyloid-β Aggregation and Enhancing Autophagy Activity
Journal of Alzheimer's Disease
2020
Astragaloside IV prevents Aβ1-42 oligomers-induced memory impairment and hippocampal cell apoptosis by promoting PPARγ/BDNF signaling pathway
Brain Research
2020
EPA-enriched ethanolamine plasmalogen and EPA-enriched phosphatidylethanolamine enhance BDNF/TrkB/CREB signaling and inhibit neuronal apoptosisin vitroandin vivo
Food & Function
2020
Human umbilical cord mesenchymal stem cells-derived exosomes deliver microRNA-375 to downregulate ENAH and thus retard esophageal squamous cell carcinoma progression
Journal of Experimental & Clinical Cancer Research
2020
Natural Products for the Treatment of Neurodegenerative Diseases
Current Medicinal Chemistry
2020
New Insights into Detection of a Dendrobine Compound From a Novel Endophytic Trichoderma longibrachiatum Strain and Its Toxicity Against Phytopathogenic Bacteria
Frontiers in Microbiology
2020
Dendrobium nobileLindl alkaloid attenuates 6‐OHDA‐induced dopamine neurotoxicity
Biotechnology and Applied Biochemistry
2020
Anti-aging properties of Dendrobium nobile Lindl.: From molecular mechanisms to potential treatments
Journal of Ethnopharmacology
2020
Dendrobium nobile Lindl. alkaloids-mediated protection against CCl4-induced liver mitochondrial oxidative damage is dependent on the activation of Nrf2 signaling pathway
Biomedicine & Pharmacotherapy
2019
Induction of Nrf2 pathway by Dendrobium nobile Lindl. alkaloids protects against carbon tetrachloride induced acute liver injury
Biomedicine & Pharmacotherapy
2019
Puerariae Radix Prevents Anxiety and Cognitive Deficits in Mice Under Oligomeric Aβ-Induced Stress
The American Journal of Chinese Medicine
2019
Reducing PRLR expression and JAK2 activity results in an increase in BDNF expression and inhibits the apoptosis of CA3 hippocampal neurons in a chronic mild stress model of depression
Brain Research
2019
Co-expression Network Analysis Revealing the Potential Regulatory Roles of lncRNAs in Alzheimer’s Disease
Interdisciplinary Sciences: Computational Life Sciences
2019
Alkaloids of dendrobium nobile lindl. Altered hepatic lipid homeostasis via regulation of bile acids
Journal of Ethnopharmacology
2019
Dendrobium alkaloids decrease Aβ by regulating α- and β-secretases in hippocampal neurons of SD rats
PeerJ
2018
Kaempferol alleviates LPS-induced neuroinflammation and BBB dysfunction in mice via inhibiting HMGB1 release and down-regulating TLR4/MyD88 pathway
International Immunopharmacology
2018
Piceatannol attenuates behavioral disorder and neurological deficits in aging mice via activating the Nrf2 pathway
Food & Function
2018
Dendrobium nobile Lindl. Alkaloids Decreases the Level of Intracellular β-Amyloid by Improving Impaired Autolysosomal Proteolysis in APP/PS1 Mice
Frontiers in Pharmacology
2018
Combined acupuncture and HuangDiSan treatment affects behavior and synaptophysin levels in the hippocampus of senescence-accelerated mouse prone 8 after neural stem cell transplantation
Neural Regeneration Research
2018
Electroacupuncture preconditioning protects against focal cerebral ischemia/reperfusion injury via suppression of dynamin-related protein 1
Neural Regeneration Research
2018
NaHS restores mitochondrial function and inhibits autophagy by activating the PI3K/Akt/mTOR signalling pathway to improve functional recovery after traumatic brain injury
Chemico-Biological Interactions
2018
A time-of-flight mass spectrometry based strategy to fast screen triterpenoids in Xanthoceras sorbifolia Bunge husks for bioactive substances against Alzheimer's disease
RSC Advances
2018
Graphene Oxide Quantum Dots Reduce Oxidative Stress and Inhibit Neurotoxicity In Vitro and In Vivo through Catalase‐Like Activity and Metabolic Regulation
Advanced Science
2018
Transplantation of hypoxic preconditioned neural stem cells benefits functional recovery via enhancing neurotrophic secretion after spinal cord injury in rats
Journal of Cellular Biochemistry
2017
MicroRNA-107 prevents amyloid-β-induced neurotoxicity and memory impairment in mice
International Journal of Molecular Medicine
2017
Dendrobium: Sources of Active Ingredients to Treat Age-Related Pathologies
Aging and disease
2017
Dendrobium nobile Lindl. alkaloids regulate metabolism gene expression in livers of mice
Journal of Pharmacy and Pharmacology
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