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2024
Potent, Selective Agonists for the Cannabinoid-like Orphan G Protein-Coupled Receptor GPR18: A Promising Drug Target for Cancer and Immunity
Journal of Medicinal Chemistry
2024
New insights into sperm physiology regulation: Enlightenment from G‐protein‐coupled receptors
Andrology
2024
Positive allosteric modulation of the cannabinoid CB1 receptor potentiates endocannabinoid signalling and changes ERK1/2 phosphorylation kinetics
British Journal of Pharmacology
2024
Uncovering the Power of GPR18 Signalling: How RvD2 and Other Ligands Could Have the Potential to Modulate and Resolve Inflammation in Various Health Disorders
Molecules
2024
Discovery of Acylated Glycine and Alanine by Integrating Chemical Derivatization-Based LC-MS/MS and Knowledge-Driven Prediction
Analytical Chemistry
2024
GPCRs: emerging targets for novel T cell immune checkpoint therapy
Cancer Immunology, Immunotherapy
2024
Identification of robust predictors for ibrutinib response by multiomics in MYD88-mutated Waldenström macroglobulinemia
Blood Advances
2024
RAMP and MRAP accessory proteins have selective effects on expression and signalling of the CB1, CB2, GPR18 and GPR55 cannabinoid receptors
British Journal of Pharmacology
2024
GPCR kinase subtype requirements for arrestin-2 and -3 translocation to the cannabinoid CB1 receptor and the consequences on G protein signalling
Biochemical Pharmacology
2023
Kinetic insights into agonist-dependent signalling bias at the pro-inflammatory G-protein coupled receptor GPR84
European Journal of Pharmacology
2023
GPR18 and GPR55-related Ligands Serving as Antagonists or Agonists: Current Situation, Challenges and Perspectives
Medicinal Chemistry
2023
Novel GPR18 Ligands in Rodent Pharmacological Tests: Effects on Mood, Pain, and Eating Disorders
International Journal of Molecular Sciences
2023
Cannabinoid 1 (CB1) receptor arrestin subtype‐selectivity and phosphorylation dependence
British Journal of Pharmacology
2022
GPR18-Mediated Relaxation of Human Isolated Pulmonary Arteries
International Journal of Molecular Sciences
2022
A review of non-prostanoid, eicosanoid receptors: expression, characterization, regulation, and mechanism of action
Journal of Cell Communication and Signaling
2022
Structure Prediction, Evaluation, and Validation of GPR18 Lipid Receptor Using Free Programs
International Journal of Molecular Sciences
2022
Multipathway In Vitro Pharmacological Characterization of Specialized Proresolving G Protein-Coupled Receptors
Molecular Pharmacology
2022
GPR18 Agonist Resolvin D2 Reduces Early Brain Injury in a Rat Model of Subarachnoid Hemorrhage by Multiple Protective Mechanisms
Cellular and Molecular Neurobiology
2022
In Vitro Characterization of 6-Methyl-3-(2-nitro-1-(thiophen-2-yl)ethyl)-2-phenyl-1H-indole (ZCZ011) at the Type 1 Cannabinoid Receptor: Allosteric Agonist or Allosteric Modulator?
ACS Pharmacology & Translational Science
2022
The Impact of Resolution of Inflammation on Tumor Microenvironment: Exploring New Ways to Control Cancer Progression
Cancers
2022
Delineating the interactions between the cannabinoid CB2 receptor and its regulatory effectors; β‐arrestins and GPCR kinases
British Journal of Pharmacology
2022
GPCRs as Therapeutic Targets
2021
Methods in Cell Biology
2021
THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner
Cancers
2021
The GPR18 Agonist PSB-KD-107 Exerts Endothelium-Dependent Vasorelaxant Effects
Pharmaceuticals
2021
Effects of GPR18 Ligands on Body Weight and Metabolic Parameters in a Female Rat Model of Excessive Eating
Pharmaceuticals
2021
Fuzzy measure with regularization for gene selection and cancer prediction
International Journal of Machine Learning and Cybernetics
2021
Endocannabinoid signaling pathways: beyond CB1R and CB2R
Journal of Cell Communication and Signaling
2021
G-Protein Coupled Receptors Involved in the Resolution of Inflammation: Ligands and Therapeutic Perspectives
Mini-Reviews in Medicinal Chemistry
2021
Novel selective agonist of GPR18, PSB‐KK‐1415 exerts potent anti‐inflammatory and anti‐nociceptive activities in animal models of intestinal inflammation and inflammatory pain
Neurogastroenterology & Motility
2020
Discovery of Tricyclic Xanthines as Agonists of the Cannabinoid-Activated Orphan G-Protein-Coupled Receptor GPR18
ACS Medicinal Chemistry Letters
2020
Receptors and Channels Possibly Mediating the Effects of Phytocannabinoids on Seizures and Epilepsy
Pharmaceuticals
2020
Signalling profiles of a structurally diverse panel of synthetic cannabinoid receptor agonists
Biochemical Pharmacology
2020
Abnormal Cannabidiol Affects Production of Pro-Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic-Microglial Cocultures
Molecules
2020
New Advances in Targeting the Resolution of Inflammation: Implications for Specialized Pro-Resolving Mediator GPCR Drug Discovery
ACS Pharmacology & Translational Science
2020
Therapeutic Exploitation of GPR18: Beyond the Cannabinoids?
Journal of Medicinal Chemistry
2019
Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures
International Journal of Molecular Sciences
2019
Fortschritte in der Cannabis-Forschung aus pharmazeutisch-chemischer Sicht
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz
2019
Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence
Frontiers in Pharmacology
2019
Modulation of the Endocannabinoid System as a Potential Anticancer Strategy
Frontiers in Pharmacology
2019
Potential metabolic and behavioural roles of the putative endocannabinoid receptors GPR18, GPR55 and GPR119 in feeding
Current Neuropharmacology
2019
Model‐free and kinetic modelling approaches for characterising non‐equilibrium pharmacological pathway activity: Internalisation of cannabinoid CB1 receptors
British Journal of Pharmacology
2019
Towards A Molecular Understanding of The Cannabinoid Related Orphan Receptor GPR18: A Focus on Its Constitutive Activity
International Journal of Molecular Sciences
2019
Advances in Experimental Medicine and Biology
2019
Do Toxic Synthetic Cannabinoid Receptor Agonists Have Signature in Vitro Activity Profiles? A Case Study of AMB-FUBINACA
ACS Chemical Neuroscience
2018
The quest for endothelial atypical cannabinoid receptor: BKCa channels act as cellular sensors for cannabinoids in in vitro and in situ endothelial cells
Vascular Pharmacology
2018
New approaches and challenges to targeting the endocannabinoid system
Nature Reviews Drug Discovery
2018
Targeting the endocannabinoid system as a potential anticancer approach
Drug Metabolism Reviews
2018
The G protein-coupled receptors deorphanization landscape
Biochemical Pharmacology
2018
N-Acyl Amino Acids (Elmiric Acids): Endogenous Signaling Molecules with Therapeutic Potential
Molecular Pharmacology
2018
Modulation of the Oxidative Stress and Lipid Peroxidation by Endocannabinoids and Their Lipid Analogues
Antioxidants
2018
Biosynthesis of D-Series Resolvins in Skin Provides Insights into their Role in Tissue Repair
Journal of Investigative Dermatology
2018
Structure-activity relationships of imidazothiazinones and analogs as antagonists of the cannabinoid-activated orphan G protein-coupled receptor GPR18
European Journal of Medicinal Chemistry
2018
Molecular and functional interaction between GPR18 and cannabinoid CB2 G-protein-coupled receptors. Relevance in neurodegenerative diseases
Biochemical Pharmacology
2018
Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines
Frontiers in Pharmacology
2018
Resolvin D2 protects against cerebral ischemia/reperfusion injury in rats
Molecular Brain
2017
Advances in Pharmacology
2017
Gαssignalling of the CB1receptor and the influence of receptor number
British Journal of Pharmacology
2017
The Orphan Receptor GPR17 Is Unresponsive to Uracil Nucleotides and Cysteinyl Leukotrienes
Molecular Pharmacology
2017
N-arachidonoyl glycine, another endogenous agonist of GPR55
Biochemical and Biophysical Research Communications
2017
The Effect of Chronic Activation of the Novel Endocannabinoid Receptor GPR18 on Myocardial Function and Blood Pressure in Conscious Rats
Journal of Cardiovascular Pharmacology
2016
Sulfation of the FLAG epitope is affected by co-expression of G protein-coupled receptors in a mammalian cell model
Scientific Reports
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