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2025
Pharmacological modulation of cellular senescence: Implications for breast cancer progression and therapeutic strategies
European Journal of Pharmacology
2025
Unraveling the alkaloid diversity and pharmacological potential of Ocimum: Integrated UPLC-MS/MS, network pharmacology, and transcriptomic insights for functional food and drug discovery
Food Research International
2025
The anticancer properties of harmine and its derivatives
Phytochemistry Reviews
2025
Resource distribution, pharmacological activity, toxicology and clinical drugs of β-Carboline alkaloids: An updated and systematic review
Fitoterapia
2023
Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer
Cell Communication and Signaling
2022
Targeting cellular senescence in cancer by plant secondary metabolites: A systematic review
Pharmacological Research
2021
Loading harmine on nanographene changes the inhibitory effects of free harmine against MCF-7 and fibroblast cells
Medicinal Chemistry Research
2021
Discovery of β-carboline-(phenylsulfonyl)furoxan hybrids as potential anti-breast cancer agents
Bioorganic & Medicinal Chemistry Letters
2021
Identification of harmine and β-carboline analogs from a high-throughput screen of an approved drug collection; profiling as differential inhibitors of DYRK1A and monoamine oxidase A and for in vitro and in vivo anti-cancer studies
European Journal of Pharmaceutical Sciences
2020
Saffron inhibits the proliferation of hepatocellular carcinoma via inducing cell apoptosis
Panminerva Medica
2020
Targeting cell cycle by β-carboline alkaloids in vitro: Novel therapeutic prospects for the treatment of cancer
Chemico-Biological Interactions
2020
Pharmacological effects of harmine and its derivatives: a review
Archives of Pharmacal Research
2020
Convergence of therapy-induced senescence (TIS) and EMT in multistep carcinogenesis: current opinions and emerging perspectives
Cell Death Discovery
2020
Cellular senescence and cancer: Focusing on traditional Chinese medicine and natural products
Cell Proliferation
2020
Circumstantial Overdose Management of an Efficient Cancer Cell Photosensitizer with Preclinical Evidence: A Biophysical Study
ACS Applied Bio Materials
2019
The chemistry of senescence
Nature Reviews Chemistry
2019
Cellular Senescence-Inducing Small Molecules for Cancer Treatment
Current Cancer Drug Targets
2018
Combining ligand-based and structure-based drug design approaches to study the structure-activity relationships of a β-carboline derivative series
Structural Chemistry
2017
Long-term exposure to MST-312 leads to telomerase reverse transcriptase overexpression in MCF-7 breast cancer cells
Anti-Cancer Drugs
2017
Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin
Mechanisms of Ageing and Development
2017
Potential Antitumor Effect of Harmine in the Treatment of Thyroid Cancer
Evidence-Based Complementary and Alternative Medicine
2017
Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation
Molecules
2016
Small molecule compounds that induce cellular senescence
Aging Cell
2016
Harmine induces cell cycle arrest and mitochondrial pathway-mediated cellular apoptosis in SW620 cells via inhibition of the Akt and ERK signaling pathways
Oncology Reports
2015
Modes of Action of Herbal Medicines and Plant Secondary Metabolites
Medicines
2015
Dose-Dependent Cytotoxic Effects of Boldine in HepG-2 Cells—Telomerase Inhibition and Apoptosis Induction
Molecules
2015
Pro-apoptotic and anti-proliferative effects of 3,3′-diindolylmethane in nasopharyngeal carcinoma cells via downregulation of telomerase activity
Molecular Medicine Reports
2015
Targeting Human Telomerase Reverse Transcriptase by a Simple siRNA Expression Cassette in HepG2 Cells
Hepatitis Monthly
2014
Growth Inhibitory Impact of Peganum harmala L. on Two Breast Cancer Cell Lines
Iranian Journal of Biotechnology
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