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2025
PDAI: A green pesticide molecule design technology platform driven by high-performance computing and artificial intelligence
Advanced Agrochem
2025
Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes
Nature Communications
2025
Integration and Innovation of AIDD and CADD: Cutting-Edge Technologies and Future Trends in Accelerating Drug Development
Journal of Diseases and Medicinal Plants
2024
The fitness cost of spurious phosphorylation
The EMBO Journal
2023
Lysine deserts prevent adventitious ubiquitylation of ubiquitin-proteasome components
Cellular and Molecular Life Sciences
2022
An evolutionarily conserved C4HC3-type E3 ligase regulates plant broad-spectrum resistance against pathogens
The Plant Cell
2022
Application of Computational Biology and Artificial Intelligence in Drug Design
International Journal of Molecular Sciences
2022
Genome-Wide Regulations of the Preinitiation Complex Formation and Elongating RNA Polymerase II by an E3 Ubiquitin Ligase, San1
Molecular and Cellular Biology
2021
The San1 Ubiquitin Ligase Avidly Recognizes Misfolded Proteins through Multiple Substrate Binding Sites
Biomolecules
2021
Nuclear Ubiquitin-Proteasome Pathways in Proteostasis Maintenance
Biomolecules
2020
Presence and structure‐activity relationship of intrinsically disordered regions across mucins
The FASEB Journal
2020
Co-Chaperones in Targeting and Delivery of Misfolded Proteins to the 26S Proteasome
Biomolecules
2020
Genetic Selection Based on a Ste6*C-HA-Ura3 Substrate Identifies New Cytosolic Quality Control Alleles in Saccharomyces cerevisiae
G3 Genes|Genomes|Genetics
2020
Protein Homeostasis Diseases
2020
Unstructured Biology of Proteins from Ubiquitin-Proteasome System: Roles in Cancer and Neurodegenerative Diseases
Biomolecules
2020
The RING Domain of RING Finger 12 Efficiently Builds Degradative Ubiquitin Chains
Journal of Molecular Biology
2019
Intrinsically Disordered Proteins
2019
Advances in Protein Chemistry and Structural Biology
2019
Biophysical and Mechanistic Models for Disease-Causing Protein Variants
Trends in Biochemical Sciences
2018
Protein Quality Control Degradation in the Nucleus
Annual Review of Biochemistry
2017
Conserved cytoplasmic domains promote Hrd1 ubiquitin ligase complex formation for ER-associated degradation (ERAD)
Journal of Cell Science
2017
Evolution of intrinsic disorder in eukaryotic proteins
Cellular and Molecular Life Sciences
2017
Blocking protein quality control to counter hereditary cancers
Genes, Chromosomes and Cancer
2017
Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations
PLOS Genetics
2017
Repair or destruction—an intimate liaison between ubiquitin ligases and molecular chaperones in proteostasis
FEBS Letters
2016
Intrinsic disorder in spondins and some of their interacting partners
Intrinsically Disordered Proteins
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